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Loss in Ubiquitin Carboxy-Terminal Hydrolase L1 Hinders Long-Term Difference Knowledge along with Metabolic Legislation in Murine Spermatogonial Base Tissue.
With the rapid development of sensor and information technology, now multisensor data relating to the system degradation process are readily available for condition monitoring and remaining useful life (RUL) prediction. The traditional data fusion and RUL prediction methods are either not flexible enough to capture the highly nonlinear relationship between the health condition and the multisensor data or have not fully utilized the past observations to capture the degradation trajectory. In this article, we propose a joint prognostic model (JPM), where Bayesian linear models are developed for multisensor data, and an artificial neural network is proposed to model the nonlinear relationship between the residual life, the model parameters of each sensor data, and the observation epoch. A Bayesian updating scheme is developed to calculate the posterior distributions of the model parameters of each sensor data, which are further used to estimate the posterior predictive distributions of the residual life. The effectiveness and advantages of the proposed JPM are demonstrated using the commercial modular aero-propulsion system simulation data set.This article studies an optimal event-triggered control (ETC) problem of nonlinear continuous-time systems subject to asymmetric control constraints. The present nonlinear plant differs from many studied systems in that its equilibrium point is nonzero. First, we introduce a discounted cost for such a system in order to obtain the optimal ETC without making coordinate transformations. Then, we present an event-triggered Hamilton-Jacobi-Bellman equation (ET-HJBE) arising in the discounted-cost constrained optimal ETC problem. After that, we propose an event-triggering condition guaranteeing a positive lower bound for the minimal intersample time. To solve the ET-HJBE, we construct a critic network under the framework of adaptive critic learning. The critic network weight vector is tuned through a modified gradient descent method, which simultaneously uses historical and instantaneous state data. By employing the Lyapunov method, we prove that the uniform ultimate boundedness of all signals in the closed-loop system is guaranteed. Finally, we provide simulations of a pendulum system and an oscillator system to validate the obtained optimal ETC strategy.Pedestrian path prediction is a very challenging problem because scenes are often crowded or contain obstacles. Existing state-of-the-art long short-term memory (LSTM)-based prediction methods have been mainly focused on analyzing the influence of other people in the neighborhood of each pedestrian while neglecting the role of potential destinations in determining a walking path. In this article, we propose classifying pedestrian trajectories into a number of route classes (RCs) and using them to describe the pedestrian movement patterns. Based on the RCs obtained from trajectory clustering, our algorithm, which we name the prediction of pedestrian paths by LSTM (PoPPL), predicts the destination regions through a bidirectional LSTM classification network in the first stage and then generates trajectories corresponding to the predicted destination regions through one of the three proposed LSTM-based architectures in the second stage. Our algorithm also outputs probabilities of multiple predicted trajectories that head toward the destination regions. We have evaluated PoPPL against other state-of-the-art methods on two public data sets. MER-29 mouse The results show that our algorithm outperforms other methods and incorporating potential destination prediction improves the trajectory prediction accuracy.We show that a neural network whose output is obtained as the difference of the outputs of two feedforward networks with exponential activation function in the hidden layer and logarithmic activation function in the output node, referred to as log-sum-exp (LSE) network, is a smooth universal approximator of continuous functions over convex, compact sets. By using a logarithmic transform, this class of network maps to a family of subtraction-free ratios of generalized posynomials (GPOS), which we also show to be universal approximators of positive functions over log-convex, compact subsets of the positive orthant. The main advantage of difference-LSE networks with respect to classical feedforward neural networks is that, after a standard training phase, they provide surrogate models for a design that possesses a specific difference-of-convex-functions form, which makes them optimizable via relatively efficient numerical methods. In particular, by adapting an existing difference-of-convex algorithm to these models, we obtain an algorithm for performing an effective optimization-based design. We illustrate the proposed approach by applying it to the data-driven design of a diet for a patient with type-2 diabetes and to a nonconvex optimization problem.We propose and demonstrate the use of a model-assisted generative adversarial network (GAN) to produce fake images that accurately match true images through the variation of the parameters of the model that describes the features of the images. The generator learns the model parameter values that produce fake images that best match the true images. Two case studies show excellent agreement between the generated best match parameters and the true parameters. The best match model parameter values can be used to retune the default simulation to minimize any bias when applying image recognition techniques to fake and true images. In the case of a real-world experiment, the true images are experimental data with unknown true model parameter values, and the fake images are produced by a simulation that takes the model parameters as input. The model-assisted GAN uses a convolutional neural network to emulate the simulation for all parameter values that, when trained, can be used as a conditional generator for fast fake-image production.Despite the competitive prediction performance, recent deep image quality models suffer from the following limitations. First, it is deficiently effective to interpret and quantify the region-level quality, which contributes to global features during deep architecture training. Second, human visual perception is sensitive to compositional features (i.e., the sophisticated spatial configurations among regions), but explicitly incorporating them into a deep model is challenging. Third, the state-of-the-art deep quality models typically use rectangular image patches as inputs, but there is no evidence that these rectangles can reflect arbitrarily shaped objects, such as beaches and jungles. By defining the complet, which is a set of image segments collaboratively characterizing the spatial/geometric distribution of multiple visual elements, we propose a novel quality-modeling framework that involves two key modules a complet ranking algorithm and a spatially-aware dual aggregation network (SDA-Net). Specifically, to describe the region-level quality features, we build complets to characterize the high-order spatial interactions among the arbitrarily shaped segments in each image.
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