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A systematic review of maternal dna as well as baby outcomes following clozapine extension while pregnant.
Aggression was significantly related to cortisol levels in men, but not in women. Similarly, trait anxiety was positively related to cortisol levels in men, but not in women. Happiness was unrelated to cortisol levels in women and men. Follow-up regressions were conducted separately for men and women. A significant model was found for cortisol in men only with trait anxiety, aggression, and the interaction between trait anxiety and aggression.

The current study builds on previous reports by showing that aggression and anxiety differentially influence the cortisol response to an acute stress in men and women.
The current study builds on previous reports by showing that aggression and anxiety differentially influence the cortisol response to an acute stress in men and women.
Changes in the hippocampus induced by water intoxication were studied using fluorescence microscopy (FM) and magnetic resonance imaging (MRI).

In three animals (rats), intracellular/extracellular distribution of Evans blue (EB) in cerebral cortex and hippocampus of both hemispheres was revealed by injection of EB into the internal carotid artery (ICA) in hyperhydrated rats (water intoxication, WI). A total of 8 experimental rats were used for the MRI study. The animals were scanned before WI, then the experimental brain edema was induced by WI and MR scanning was performed at day 1 and day 8 after WI. Besides standard T2-weighted imaging an apparent diffusion coefficient (ADC) and transverse relaxation time (T2) were evaluated.

Hyperhydration brought about the largest intracellular deposits of EB in CA3 hippocampal region, followed by the cerebral cortex and CA1 hippocampal region with the lowest amount of intracellular EB in the dentate gyrus. A higher apparent diffusion coefficient (corresponding to a vasogenic edema) was found the first day after hyperhydration in the cortex and in the CA1 and CA3 regions with no changes in dentate gyrus.

Both FM and MRI confirmed a selectively higher vulnerability tohyperhydration and hyponatremia (achieved by water intoxication) of the hippocampal cells compared to dentate gyrus cells.
Both FM and MRI confirmed a selectively higher vulnerability to hyperhydration and hyponatremia (achieved by water intoxication) of the hippocampal cells compared to dentate gyrus cells.Pseudotumor cerebri, benign intracranial hypertension or idiopathic intracranial hypertension are all terms used for a neurological syndrome consisting of increased intracranial pressure, headache and possible edema of the optic nerve head and decreased visual function. Normal findings in contrast agent computed tomography or magnetic resonance imaging of the head in physiological neurological findings, with the exception of paresis VI, indicate an increase in pressure of laboratory normal cerebrospinal fluid (CSF) of unknown cause. In this article we describe what idiopathic intracranial hypertension is, what manifestations can occur from an ophthalmological point of view and how to treat them. Case report The 47 years old female patient was sent for a consultation examination to the neurophthalmologic outpatient clinic of the Department of Ophthalmology, Comenius University, Bratislava. She reported about one and a half years of headache and impaired visual function. After repeated examinations in neurology, neurosurgery and ophthalmology outpatient clinic an edema of the optic nerve head was found. The patient was sent again for neurosurgical check-up. The lumboparietal drainage was performed. The patient continued to be monitored and received interdisciplinary treatment that resulted in the patient's central visual acuity decreasing slightly, but without loss of vision.Chlamydia pneumoniae (C. selleckchem pneumoniae) is an obligate intracellular bacterial pathogen, which has long been investigated as a potential developmental or exacerbating factor in various pathologies. C. pneumoniae infects mainly the respiratory tract, but also has been associated with extrarespiratory manifestations. We report on an uncommon case of young patient with acute acalculous cholecystitis (AAC) and acute pericarditis during the chlamydia pneumoniae infection with hematogenous / lymphogenous routes of systemic dissemination of Chlamydia pneumoniae infection.
Cushing disease is a rare but serious endocrine disorder. It involves increased cortisol levels, which can damage the function of various systems throughout the body, including the central nervous system, affecting cognition, memory, and emotion. However, it is rare that Cushing disease presents as a mental disorder. This paper reports the complete diagnosis, treatment process, and follow-up of a patient with Cushing disease whose main symptom was bipolar disorder.

A 31-year-old woman was diagnosed with bipolar disorder 9 years ago and was admitted to hospital several times due to repeated episodes of depression and mania. In October 2017, after careful examination and consideration by doctors, the patient was diagnosed with Cushing syndrome and underwent transsphenoidal pituitary microadenoma resection. Glucocorticoid replacement therapy and antipsychotic therapy were administered postoperatively. After careful treatment and care by the medical staff, the patient's cortisol levels returned to normal, and her mental symptoms were significantly improved.

This is a rare case of Cushing disease marked by psychiatric symptoms. Neuropsychiatric symptoms can precede the onset of Cushing disease, making diagnosis challenging.
This is a rare case of Cushing disease marked by psychiatric symptoms. Neuropsychiatric symptoms can precede the onset of Cushing disease, making diagnosis challenging.
Thoracotomy, video-assisted thoracoscopic surgery (VATS) and robotic assisted thoracoscopic surgery (RATS)-lobectomy are widely accepted procedures for the surgical treatment of clinical (c)stage I non- small cell lung cancer (NSCLC). In the current literature which procedure gives more benefits is still debated. We present a comparison between these three procedures in term of advantages and postoperative outcomes.

A multicentric study about 259 lobectomies from 2013 to 2019 128 patients underwent TL, 96 VATS and 35 RATS. Different variables were retrospectively analyzed among these three cohorts of patients with diagnosis of cStage I NSCLC.

Rate of major complications comparable in VATS, RATS and TL; Advantages for RATS in minor complications (TL 34.4% vs. VATS 18.75% vs. RATS 8.57%. P=0.0015), postoperative days in Intensive Care Unit, days to chest tube removal, length of postoperative hospitalization (P<0.0001) and number of lymph nodes dissected (P=0.0257). Operating times are shorter in VATS than RATS (P<0.
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