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ADHD Medication During Pregnancy and Breastfeeding
The decision to stop or continue ADHD medication during pregnancy and nursing is challenging for women with the condition. There aren't many studies on how long-term exposure may affect the pregnant fetus.
A recent study published in Molecular Psychiatry demonstrates that children exposed to ADHD medication during pregnancy do not develop neurological problems like hearing loss or vision, febrile seizures or IQ impairment. The authors acknowledge the need for more high-quality research.
Risk/Benefit Analysis
Women who are expecting and taking ADHD medication must consider the benefits of taking it versus the risks to the fetus. Physicians do not have the necessary data to make unequivocal recommendations but they can provide information on benefits and risks that can aid pregnant women in making informed decisions.
A study published in Molecular Psychiatry found that women who took ADHD medications during early pregnancy did not face an higher risk of fetal cardiac malformations or major structural birth defects. Researchers conducted a massive population-based study of case control to compare the incidence of major structural defects in infants born to mothers who used stimulants during pregnancy. Pediatric cardiologists, clinical geneticists and other experts examined the cases to confirm that the classification was correct and to reduce any bias.
However, the researchers' study had its limitations. The researchers were not able to, in the first place, to separate the effects caused by the medication from the disorder. This limitation makes it difficult to determine whether the small differences observed in the groups that were exposed are due to the use of medication or comorbidities that cause confusion. Researchers also did not examine long-term outcomes for the offspring.
The study revealed that babies whose mothers had taken ADHD medication during pregnancy had a slightly higher chance of being admitted to the neonatal care unit (NICU) in comparison to those whose mothers didn't take any medication during pregnancy or stopped taking their medication before or during pregnancy. The reason for this was central nervous system disorders. The increased risk of admission was not affected by the stimulant medications used during pregnancy.
Women who took stimulant ADHD medication during pregnancy were also at an increased chance of having a caesarean birth or having a baby with low Apgar score (less than 7). These increases did appear to be independent of the type of medication taken during pregnancy.
The researchers suggest that the small risk associated with the use of ADHD medications during early pregnancy may be offset by the greater benefits to both the mother and child of continuing treatment for the woman's disorder. Physicians should discuss the issue with their patients and, when possible, assist them in developing strategies to improve their coping abilities that can lessen the effects of her disorder on her daily functioning and relationships.
Medication Interactions
As more women than ever are being diagnosed with ADHD and treated with medication, the issue of whether to keep or stop treatment during pregnancy is a question that more and more doctors confront. Most of the time, these decisions are made without solid and reliable evidence either way, so physicians must weigh their knowledge, the experiences of other doctors, and what research suggests about the subject, along with their own best judgment for each individual patient.
In particular, the issue of potential risks for the baby can be a challenge. Many studies on this subject are based on observational evidence rather than controlled research, and their findings are often contradictory. Most studies limit their analysis to live-births, which could underestimate the teratogenic impact that can lead to abortions or terminations of pregnancy. The study that is discussed in this journal club addresses these limitations by analyzing data on live and deceased births.
Conclusion A few studies have shown a positive correlation between ADHD medications and certain birth defects, other studies have not shown such a relationship. Most studies show an unintended, or slightly negative, effect. In each case it is imperative to conduct a thorough evaluation of the benefits and risks is required.
It can be difficult, if not impossible for women suffering from ADHD to stop taking their medication. In an article published in Archives of Women's Mental Health, psychologist Jennifer Russell notes that stopping ADHD medication during pregnancy can lead to increased depression, feelings of isolation and family conflict for patients with ADHD. The loss of medication can also affect the ability to drive safely and to perform work-related tasks which are essential aspects of everyday life for people with ADHD.
She suggests that women who aren't sure whether to continue taking medication or discontinue it due to pregnancy educate family members, coworkers, and acquaintances about the condition, the impact on daily functioning and the benefits of keeping the current treatment. It can also help a woman feel confident about her decision. It is also worth noting that certain drugs can pass through the placenta so if a woman decides to discontinue her ADHD medication during pregnancy and breastfeeding, she should be aware that the effects of the medication could be transferred to the infant.
Birth Defects Risk
As the use and abuse of ADHD medications to treat the symptoms of attention deficit disorder hyperactivity disorder (ADHD) increases as does the concern about the possible effects of the drugs on foetuses. Recent research published in the journal Molecular Psychiatry has added to the body knowledge on this topic. Researchers used two massive datasets to analyze over 4.3 million pregnancies and determine if the use of stimulant medications increased the risk of birth defects. While the overall risk remains low, the researchers discovered that the first-trimester exposure to ADHD medications was associated with an increase in the risk of certain heart defects, such as ventriculoseptal defect (VSD).
The authors of the study didn't find any association between early use of medication and congenital anomalies like facial deformities, or club feet. The findings are in line with previous studies revealing a small but significant increase in the risk of developing cardiac malformations in women who started taking ADHD medications before the time of pregnancy. The risk grew in the later part of pregnancy, when a lot of women decide to stop taking their medication.
Women who took ADHD medication in the first trimester were more likely to require a caesarean birth, have a low Apgar after delivery and had a baby that required help breathing at birth. The researchers of the study were unable to eliminate selection bias because they limited the study to women who did not have any other medical conditions that might have contributed to the findings.
The researchers hope their research will aid in the clinical decisions of physicians who encounter pregnant women. The researchers suggest that while discussing risks and benefits are important, the choice regarding whether or not to stop taking medication should be according to the severity of each woman's ADHD symptoms and her needs.
The authors also caution that, while stopping the medication is an option, it isn't an option that is recommended due to the high rate of depression and other mental health issues in women who are pregnant or who are recently postpartum. Additionally, the research suggests that women who choose to stop taking their medications are more likely to experience a difficult time getting used to life without them after the baby's arrival.
Nursing
It can be overwhelming becoming a mother. Women with ADHD who must work through their symptoms while attending physician appointments as well as getting ready for the arrival of a child and adapting to new routines in the home may face a lot of challenges. Many women choose to continue taking their ADHD medication during pregnancy.
The majority of stimulant drugs are absorbed through breast milk in very small amounts, therefore the risk to the breastfeeding infant is minimal. However, the amount of exposure to medications by the newborn can vary depending on dosage, how often it is administered and the time of the day the medication is administered. In addition, various medications enter the baby’s system via the gastrointestinal tract or through breast milk. The effect on a newborn's health is not fully comprehended.
Some physicians may discontinue stimulant medications during a woman's pregnancy due to the lack of research. It is a difficult decision for the woman, who must weigh the advantages of continuing her medication against the risks to the foetus. In the meantime, until more information is available, GPs may inquire about pregnant patients whether they have any background of ADHD or if they intend to take medication during the perinatal period.
Many studies have shown that women can continue to take their ADHD medication safely during pregnancy and while breast-feeding. In the end, an increasing number of patients opt to do this and, after consulting with their doctor, they have found that the benefits of maintaining their current medication far exceed any risk.
It's important for women with ADHD who are considering breastfeeding to seek out a specialist psychiatrist's advice prior becoming pregnant. They should discuss their medication with their physician and discuss the advantages and disadvantages of continued treatment, including non-pharmacological strategies. Psychoeducation is also required to help women with ADHD recognize their symptoms and underlying disorder, learn about available treatment options and strengthen existing coping strategies. This should be a multidisciplinary approach, which includes the GP doctors, obstetricians and psychiatrists. adhd medication uk should consist of a discussion of a treatment plan for the mother and the child, as well as monitoring for indicators of deterioration, and, if necessary adjustments to the medication regimen.
Website: https://elearnportal.science/wiki/A_Look_At_The_Secrets_Of_ADHD_Stimulant_Medication
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