Notes

iDHS-DT: Determining DNase I oversensitive internet sites by adding Genetic make-up dinucleotide along with trinucleotide details.
Introduction Diabetes is a health problem on the rise in developing countries like Nepal. Often in the suburban and rural areas, patients are diagnosed in the late stages with complications. Lithium Chloride in vivo The aim of this study is to find out the prevalence of diabetes type 2 in a community hospital of Nepal. Methods This is a descriptive cross-sectional study done in a community hospital from January to March of 2019 after ethical clearance (Registration number 150320192) from the institutional review committee of Kathmandu Medical College. Convenient sampling technique was used. Glucometer using glucose sticks is used to measure random blood sugar level and relevant questions were asked in a short interview. The data were analyzed using the Statistical Package for the Social Sciences 20 version. Results Out of a total of 114 people, the prevalence of type 2 diabetes mellitus was 5 (4.38%). Among those 5 (4.385%) people with type 2 diabetes mellitus, 2 (1.75%) were female and 3 (2.63%) were male. The minimum age of the patient was 17 years and the maximum age was 92 years. Five out of 95 patients with mild physical activity had random blood sugar more than 200 mg/dl and five out of 46 alcoholic patients had random blood sugar levels more than 200 mg/dl. Only 1 out of 26 smokers had a random blood sugar level of more than 200 mg/dl. Conclusions Prevalence of diabetes mellitus type 2 in our study population is quite high. Early detection of diabetes mellitus type 2 can be a good screening tool for early treatment and prevention of complications.Introduction Congenital malformations have emerged as a major cause of stillbirths and neonatal mortality. It is a common cause of morbidity and mortality not only in the newborn but also in childhood and beyond. The objective of this study was to find the prevalence of congenital malformation at birth. Methods The descriptive cross-sectional study was conducted among 2456 live births in Kathmandu Medical College and Teaching Hospital from April 2017 to March 2018 after obtaining ethical approval from the institutional review committee (Ref no. 08052017). A convenient sampling method was applied. All the live-born babies delivered in this hospital during the study period were clinically examined for the presence of congenital anomalies. All malformations were classified according to the International Classification of Diseases-10 classification. The mothers of the newborns with congenital malformations were interviewed in a predesigned proforma. Statistical analysis was done using statistical package for the social sciences version 20. Results Out of 2456 examined live births, congenital malformations were observed in 66 cases. The prevalence of congenital malformation was 66 (2.6%) at 95% confidence interval (4.19-1.98) of total live births. The genitourinary system was the most common system involved with congenital malformations being 16 (24.2%), followed by musculoskeletal system 14 (21.2%), and cardiovascular system 12 (18.2%). Conclusions Congenital malformation plays a major role in the mortality and morbidity of neonates as well as children. The genitourinary system was the most common system involved.Introduction The period of adolescence undergoes many physical and mental changes. Changing emotional and physical status along with increasing social, family, and academic pressure lead to various impairments in the mental health of adolescents. Academic failure leads to the suicide rate in adolescents, predominantly high during the declaration of exam results which is significantly high in a rural area in comparison with urban. The study examined the prevalence of academic stress among high school students in a rural area of Rolpa, Nepal. Methods A descriptive cross-sectional study was conducted in 6 schools in Rolpa from July to October 2019. The sample size calculated was 521. A convenient sampling technique was used for this study. The target population was adolescents enrolled in high schools of Rolpa. Ethical approval was taken before data collection. The scale for assessing academic stress was used to find out the prevalence. A questionnaire was translated in local language and pre-testing was done in Nepal Police School,Sanga among 10% of the calculated sample size. Data entry was done in Statistical Package for the Social Sciences version 18. Descriptive statistical analysis was done for prevalence calculation. Results Out of a total of 521 students, the prevalence of academic stress was seen among 138 (26.5%)students at a 95% confidence interval (22.72-30.28). Conclusions The prevalence of academic stress in our study was high and was consistent with other South Asian studies. Understanding academic stress and providing help and support to the students would help ease the burden for them.Introduction Patient satisfaction is an important and commonly used valid indicator for the measurement of service quality. Patient responses to healthcare services are one of the best ways to obtain information about patient views regarding the quality of healthcare. The main aim of the study was to find out the patient's satisfaction level in the tertiary care center. Methods A descriptive cross-sectional study was conducted among 94 outpatients at a tertiary care center. Data were collected after obtaining ethical clearance from the institutional review committee. Patients were selected conveniently who visited any four of the major department. We collected demographic data and the patient satisfaction towards outpatient clinic experience was studied. We used the Patient Satisfaction Questionnaire-18 to assess patient satisfaction. Data were entered and analyzed in Statistical Package for the Social Sciences version 23. The mean score and the standard deviation were calculated. Results Overall satisfaction was 74.78% with a mean value of 3.7394±0.40128. The highest satisfaction score was found in regards to the interpersonal manner of health personnel (4.2872±0.61561) followed by communication (3.9628±0.40982) and the lowest was seen in accessibility and convenience (3.2394±0.81478). Conclusions The mean score and percentage of patient satisfaction were high in the hospital. However, the accessibility and availability of medical personnel were only a matter of concern.
Read More: https://www.selleckchem.com/products/lithium-chloride.html