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This generalizability analysis of the WHiTE-3 trial found that the inferences from the trial can be generalized to a wider population of individuals in the UK NHFD and the WHiTE-cohort who met the inclusion criteria for WHiTE-3.
This generalizability analysis of the WHiTE-3 trial found that the inferences from the trial can be generalized to a wider population of individuals in the UK NHFD and the WHiTE-cohort who met the inclusion criteria for WHiTE-3.
When the probability of being cited depends on the outcome of that study, this is called citation bias. The aim of this study is to assess the determinants of citation and how these compare across six different biomedical research fields.
Citation network analyses were performed for six biomedical research questions. After identifying all relevant publications, all potential citations were mapped together with the actually performed citations in each network. As determinants of citation we assessed the following study outcome, study design, sample size, journal impact factor, gender, affiliation, authority and continent of the corresponding author, funding source, title of the publication, number of references, and self-citation. Random effect logistic regression analysis was used to assess these factors.
Four out of six networks showed evidence for citation bias. Self-citation, authority of the author, and journal impact factor were also positively associated with the probability of citation in all networks.
The probability of being cited seems associated with positive study outcomes, the authority of its authors, and the journal in which that article is published. In addition, each network showed specific characteristics that impact the citation dynamics and that need to be considered when performing and interpreting citation analyses.
The probability of being cited seems associated with positive study outcomes, the authority of its authors, and the journal in which that article is published. In addition, each network showed specific characteristics that impact the citation dynamics and that need to be considered when performing and interpreting citation analyses.
Having a senior surgeon present for high-risk patients is an important safety measure in emergency surgery, but 24-h consultant cover is not efficient. We aimed to develop a user-friendly toolbox (risk identification, outcome prediction and patient stratification) to support when to involve a senior surgeon.
We included 11,901 general surgery patients (10.0% emergencies) in a multicenter prospective cohort in China (2015-2016). Patient information and surgeons' seniority were compared between emergency and elective surgery with the same procedure codes. Risk indicators common in these two surgical timings and specific to emergency surgery were identified, and their clinical importance was evaluated by a working group of 48 experienced surgeons. Predictive models for mortality and morbidity were built using logistic regression models. Stratification rules were created to balance patients' risk and surgeons' caseload with an Acute Call Team (ACT) model.
Emergency patients had significantly higher risks ofhow the practical feasibility of using a risk assessment tool to direct senior surgeons' involvement in emergency general surgery.
Currently, Brazil is experiencing one of the fastest increasing coronavirus disease (COVID-19) mortality rates worldwide, with a minimum of 158,000 confirmed deaths presently. The city of São Paulo is particularly vulnerable because it is the most populated city in Brazil. Thus, this study aimed to analyse COVID-19 mortality in a spatiotemporal context in São Paulo, with respect to socio-economic levels.
We modelled the deaths using spatiotemporal architectures and Poisson probability distributions using a latent Gaussian Bayesian model approach.
Both total deaths and confirmed deaths showed similar spatial patterns. Mortality was higher in men and increased with age. The most critical period regarding mortality occurred between the 20th and 23rd epidemiological weeks, followed by an apparent stabilisation of the epidemiological trend. The risk of death was greater in areas with the worst social conditions during the study period. However, this pattern was not uniform over time, since we identified a shift of high risk from the areas with the best socio-economic conditions to those with the worst conditions.
Our study corroborated the relationship between COVID-19 mortality and socio-economic conditions, revealing the importance of geographic screening in the integration of better actions to face the pandemic.
Our study corroborated the relationship between COVID-19 mortality and socio-economic conditions, revealing the importance of geographic screening in the integration of better actions to face the pandemic.
Many tropical clinics offer post-travel screening for parasitic infections in asymptomatic travellers. However, literature on attack rates and incidence rates of parasitic infections is scarce.
All military personnel returning from a tropical region during the year 2018 were tested for the presence of antibodies against Strongyloides stercoralis, Schistosoma and Entamoeba histolytica. Test results were compared with previous results if available to distinguish recent and old infection.
In total, 949 soldiers were included in the study. The median age was years 31 (IQR 26-41), 96.3% were male. The median duration of stay in the tropics was 35 days (IQR 14-90). The destination was predominantly central Africa. Serological tests were positive for S. stercoralis in 10 patients (1.1%), Schistosoma in 3 (0.3%), and E. histolytica in 16 (1.7%). The attack rates were 0.84, 0.32 and 1.69 respectively. The incidence rates were 3.99, 1.49 and 7.97 respectively.
The risk for parasitic infection in the asymptomatic returning soldiers is low. VOOhpic However, the potentially serious complications of unrecognised parasitic infection can legitimise systematic screening.
The risk for parasitic infection in the asymptomatic returning soldiers is low. However, the potentially serious complications of unrecognised parasitic infection can legitimise systematic screening.
My Website: https://www.selleckchem.com/products/vo-ohpic.html
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