Notes

Effect of paeonol in growth, apoptosis, migration, invasion as well as glutamine regarding abdominal cancer tissue by way of circSFMBT2/miR-665 axis.
etal pain, your physical therapist might recommend web-based pain education as treatment to help you reduce pain intensity and disability.
If you have chronic musculoskeletal pain, your physical therapist might recommend web-based pain education as treatment to help you reduce pain intensity and disability.
The purposes of this study were to identify and describe the attributes of excellence and innovation in professional pediatric physical therapy education and develop a conceptual framework identifying dimensions of excellence.

A multi-method, case study design based on a grounded theory framework was used. Data collection included review of artifacts, field interviews (individual and focus group). A constant-comparative method for within case and across case was used for data analysis to verify and revise coding scheme, identify categories and subcategories, revise emerging themes, and develop a conceptual framework.

Based on results of a predetermined grading rubric, 6 of 17 self-nominated academic sites were selected representing diverse institution types (public/private, Carnegie classification, size) and geographic locations. Pedagogical approaches and method of content delivery varied among programs; all utilized the essential core competencies. The core pediatric faculty member(s) were Board Certi excellence. The model can serve as a guide for best practice in pediatric physical therapy education.
Results of this study are important to professional physical therapist education administrators, pediatric academic faculty, and clinical educators as they represent our understanding of the attributes of excellence. The model can serve as a guide for best practice in pediatric physical therapy education.
Imbalance and fatigue are among the most common and disabling symptoms of multiple sclerosis (MS). Vestibular rehabilitation studies demonstrate not only improvements in balance but fatigue also, suggesting a relationship between central vestibular integration and fatigue. The objective of this study was to determine whether the relationship between balance and fatigue in people with MS is seen between other measures of central vestibular integration and fatigue and to understand how central vestibular integration measures interrelate.

This cross-sectional study consisted of 40 people with MS (ages of 27-55years, Expanded Disability Severity Scale score of 1.0-6.5) who completed vestibular ocular reflex testing, subjective visual vertical testing, static posturography, dynamic gait, 2 self-report fatigue surveys, and a 6-Minute Walk Test to assess walking capacity/physical fatigue was completed. Spearman correlations were calculated between variables.

Measures of central vestibular integration were sign future studies of vestibular rehabilitation should include fatigue as a secondary outcome measure as vestibular function and fatigue may share similar a similar etiology in people with MS.
The APTA's Vision Statement for the profession is guided by principles of innovation, access, equity, and advocacy, which calls on physical therapists to stretch their influence beyond the walls of the clinic and the individuals they treat. Access and equity are problems that span multiple health care professions and entities; yet, addressing social determinants of health (SDOH) is a paradigm shift that clinicians' need continued support to achieve. This paper has two objectives (1) to define the Fundamental Cause Theory (FCT) and the Socioecological Model (SEM) within the context of physical therapy in order to promote best clinical practice and (2) to apply the concept of "fundamental interventions" in clinical practice to mitigate the negative impact of downstream effects of social determinants of health across levels of the SEM-individual, interpersonal, institutional, community, and societal. This theoretical lens provides the conceptual framework necessary for physical therapists to think creatively an no longer subscribe to a narrow scope of practice focused on individual attainment of therapy goals. This Perspective discusses FCT and SEM theoretical frameworks that can help physical therapists develop, test, and implement functional interventions to address the needs of society as a whole.
To examine the immediate effects of movement training aimed at improving use of gluteus maximus (GMAX) in the sagittal plane on hip internal rotation and self-reported patellofemoral pain (PFP) during single-limb landing.

Seventeen females with PFP participated. Lower extremity kinematics and kinetics, GMAX activation, and self-reported PFP were obtained before and after a single-session movement training program aimed at increasing the use of GMAX. Dependent variables of interest included self-reported PFP, average GMAX activation, average hip extensor moment, and peak hip internal rotation. Post-training changes were evaluated using paired t-tests and Wilcoxon Signed Rank tests.

Following movement training, self-reported PFP decreased significantly [3.9 (1.1) vs 0.8 (1.3) on a 0 to 10 scale]. Additionally, significant increases were observed for the average hip extensor moment [0.6 (0.3) vs 1.8 (0.4) Nm/kg] and average GMAX activation [41.0 (18.3) vs 51.6 (25.7) % maximum voluntary isometric contraction; P= .038] whereas peak hip internal rotation decreased significantly [8.5 (5.8) vs 6.0° ± 5.3°].

Movement training aimed at improving the use of GMAX in the sagittal plane resulted in clinically relevant changes in self-reported pain, GMAX activation, and hip kinetics and kinematics. Selleck Veliparib Improving the use of GMAX during movement merits consideration when designing rehabilitation programs for females with PFP.

The current study highlights the clinical utility of movement training for persons with PFP and provides a biomechanical rationale for its use as a potential intervention in this population.
The current study highlights the clinical utility of movement training for persons with PFP and provides a biomechanical rationale for its use as a potential intervention in this population.
Predictors of deaths of despair, including substance use disorder, psychological distress, and suicidality, are known to be elevated among young adults and recent military veterans. Limited information is available to distinguish age effects from service-era effects. We assessed these effects on indicators of potential for deaths of despair in a large national sample of U.S. adults aged ≥19 years.

The study was a retrospective, cross-sectional analysis of publicly available data for 2015-2019 from 201,846 respondents to the National Survey on Drug Use and Health (NSDUH), which measures psychological symptoms and substance use behaviors using standardized scales and diagnostic definitions. Indicators of potential for a death of despair included liver cirrhosis, past-year serious suicidal ideation, serious psychological distress per the Kessler-6 scale, and active substance use disorder (e.g., binge drinking on ≥5 occasions in the past month, nonmedical use of prescribed controlled substances, and illicit drug use).
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