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Mediating role of subconscious capital inside the romantic relationship among support and remedy stress between elderly sufferers along with chronic obstructive lung disease.
Statistical analysis included ANOVA and multiple regression to evaluate the differences. Results PD patients with high pareidolia counts were older with lower scores on neuropsychological tests. Their pre-stimulus EEG low-alpha band showed a tendency towards higher frontal activity (p=0.07). Graph networks showed increased normalized clustering coefficient (p=0.05), higher local parietal cortex efficiency (p=0.049) and lower frontal degree centrality (p=0.005). These network indices correlated positively to patients' pareidolia scores. Discussion We suggest that pareidolias in PD are a consequence of an abnormal top-down modulation of visual processing which are defined by their frontal low-alpha spectral and network alterations in the pre-stimulus phase due to a dissonance between patients' internally generated mental-processing with external stimuli.Background Brain interdependencies can be studied from either a structural/anatomical perspective ("structural connectivity") or by considering statistical interdependencies ("functional connectivity" [FC]). Interestingly, while structural connectivity is by definition pairwise (white-matter fibers project from one region to another), FC is not. However, most FC analyses only focus on pairwise statistics and they neglect higher order interactions. A promising tool to study high-order interdependencies is the recently proposed O-Information, which can quantify the intrinsic statistical synergy and the redundancy in groups of three or more interacting variables. Methods We analyzed functional magnetic resonance imaging (fMRI) data obtained at rest from 164 healthy subjects with ages ranging in 10 to 80 years and used O-Information to investigate how high-order statistical interdependencies are affected by age. Results Older participants (from 60 to 80 years old) exhibited a higher predominance of redundant dependencies compared with younger participants, an effect that seems to be pervasive as it is evident for all orders of interaction. In addition, while there is strong heterogeneity across brain regions, we found a "redundancy core" constituted by the prefrontal and motor cortices in which redundancy was evident at all the interaction orders studied. Discussion High-order interdependencies in fMRI data reveal a dominant redundancy in functions such as working memory, executive, and motor functions. Our methodology can be used for a broad range of applications, and the corresponding code is freely available.Background Graph theory and connectomics are new techniques for uncovering disease-induced changes in the brain's structural network. Most prior studied have focused on network statistics as biomarkers of disease. However, an emerging body of work involves exploring how the network serves as a conduit for the propagation of disease factors in the brain and has successfully mapped the functional and pathological consequences of disease propagation. In Alzheimer's disease (AD), progressive deposition of misfolded proteins amyloid and tau is well-known to follow fiber projections, under a "prion-like" trans-neuronal transmission mechanism, through which misfolded proteins cascade along neuronal pathways, giving rise to network spread. Methods In this review, we survey the state of the art in mathematical modeling of connectome-mediated pathology spread in AD. Then we address several open questions that are amenable to mathematically precise parsimonious modeling of pathophysiological processes, extrapolated to t point to several open and unaddressed questions and controversies that future practitioners can tackle.Background Aging is accompanied by a gradual deterioration in multiple cognitive abilities and brain structures. Both cognitive function and white matter (WM) structure are found to be associated with neurodegeneration diseases and correlated with sex during aging. However, it is still unclear whether the brain structural change could be attributable to sex, and how sex would affect cognitive performances during aging. Proteasome inhibitor Materials and Methods Diffusion magnetic resonance imaging (MRI) scans were performed on 1127 healthy participants (age range 21-89) at a single site. The age trajectories of the WM tract microstructure were delineated to estimate the turning age and changing rate between sexes. The canonical correlation analysis and moderated mediation analysis were used to examine the relationship between sex-linked WM tracts and cognitive performances. Results The axon intactness and demyelination of sex-linked tracts during aging were multifaceted. Sex-linked tracts in females peak around 5 years later than those in males but change significantly faster after the turning age. Projection and association tracts (e.g., corticospinal tracts and parahippocampal cingulum) contributed to a significant decrease in visuospatial functions (VS) and executive functions (E). We discovered that there is a stronger indirect effect of sex-linked tracts on cognitive functions in females than in males. Conclusion Our findings suggest that the vulnerable projection and association tracts in females may induce negative impacts on integrating multiple functions, which results in a faster decrease in VS and E.
To investigate the potential for decreasing radiation dose when utilizing a third generation versus second generation dual-source dual-energy CT scanner, while maintaining diagnostic image quality and acceptable image noise.

Retrospective analysis of patients who underwent dual-source dual-energy CT (dsDECT) for clinical suspicion of urolithiasis from 10/2/2017 - 9/5/2018. Patient demographics, body mass index, abdominal diameter, scanning parameters, and CT dose index volume (CTDIvol) were recorded. Image quality was assessed by measuring the attenuation and standard deviation (SD) regions of interest in the aorta and in the bladder. Image noise was determined by averaging the SD at both levels. Patients were excluded if they had not undergone both 3rd and 2nd generation DECT, time between DECT was more than 2 years, or scan parameters were outside standard protocol.

117 patients met inclusion criteria. Examinations performed on a 3rd generation DECT had an average CTDIvol 12.3 mGy, while examinations performed on a 2nd generation DECT had an average CTDIvol 13.
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