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03 mg Cd.kg-1 FM (fresh matter), 0.09-0.2 mg Pb.kg-1 FM (fresh matter), and in leek were in the range of, 0.07-0.13 mg Cd.kg-1 FM (fresh matter), and 0.3-0.5 mg Pb.kg-1 FM (fresh matter). Based on the obtained BAF values, we can conclude that the genus Allium does not belong to the accumulator of evaluated hazardous metals. Safe food production requires constant monitoring of hazardous metals in raw materials of plant origin, as these metals can have serious negative effects on human health.The paper aimed to evaluate the degree of contamination of honey available on the Polish market with cadmium (Cd) and lead (Pb). The analyses involved 49 samples of honey monofloral (n = 24) linden, raspberry, goldenrod, bean, dandelion, buckwheat and rapeseed honey, multifloral honey (n = 17) and coniferous honeydew honey (n = 8). The content of Cd and Pb was determined using Inductively Coupled Plasma-Optical Emission Spectrometers (ICP-OES). The content of Cd and Pb was confirmed in all the analysed honeys, but in 18% of samples the level of Cd was dandelion honey. It should be emphasised that consuming 19 g of honey a week (mean honey consumption in Poland) is safe for human health, as it results in an intake of Cd at the level of 1.18E-04% PTWI and 0.553% PTWI for children and an intake of Pb at the level of 0.641% BMDL01 for adults and 5.916% BMDL for children. The obtained results lead to a conclusion that the risk of disorders related to chronic exposure to Cd and Pb ingested with honey is very low, which is demonstrated by the fact that both children and adults showed CDI, CR, THQ and HI that were lower than 1.The elemental contents and the phytochemical components of Moringa oleifera are crucial for nutrition and medical purposes. Therefore, the monthly and seasonal variations of the elemental composition and phytochemical analysis of Moringa oleifera leaves collected from the same ecological area have been investigated. Diphenyleneiodonium For this purpose, Moringa oleifera leaves were collected monthly from the same tree's branches during the whole year from January 2019 to December 2019. A non-destructive elemental analysis technique was used, namely energy-dispersive X-ray fluorescence spectrometry. The seasonal variations are different from one season to another. The highest concentrations of Mo, Cr, Fe, Ti, and Si were found during winter, whereas the highest concentrations of Br, Cl, and Cu were found during the summer seasons. Based on Pearson's correlation analysis, a strong correlation between Ca and Sr was found, whereas Sr has a negative correlation with other detected elements. Similarly, Cu and Zn as well as Br and Cl have a strong correlation. Remarkable different concentrations were found during May which has the lowest positive correlation. The phytochemical analysis revealed that Moringa oleifera leaves collected during the spring season resulted in the highest chlorophyll content, phenol content, and the greatest scavenging activity. Therefore, the mineral contents and phytochemical compounds are affected by the changing of the seasons of the year. Collectively, the current results are useful for optimizing the harvest time of Moringa oleifera leaves with respect to the quality.Cadmium exposure may increase the risk of osteoporosis. However, there is no quick method to get bone mineral density (BMD) unless dual-energy X-ray absorptiometry (DXA) examinations were performed. In the present study, we aimed to identify associated factors to osteoporosis and fracture in a Chinese female population with cadmium exposure and develop nomograms to predict the risk. A total of 488 women was included in this study. Cadmium in blood (BCd) and urine (UCd) were determined as exposure biomarkers. BMD was determined using single-photon absorptiometry. Urinary N-acetyl-β-d-glucosaminidase (UNAG) and urinary albumin (UALB) were determined as renal function biomarkers. Osteoporosis was defined if T-score less then - 2.5. Multiple logistic regression showed that age, BCd, and menopausal status were independent risk factors for osteoporosis. The odds (OR) value was 1.19 (95% confidence interval (CI) 1.14-1.25) for age, 1.05 (95% CI 1.004-1.10) for BCd, and 4.75 (95% CI 1.65-13.69) for menopausal status after adjusting with cofounders. Age and UCd were the independent risk factors for bone fracture. Nomograms were developed based on the associated factors. Age was the main determinant for osteoporosis or fracture. Receiver operating curve showed acceptable performance in predicting osteoporosis (area under the curve (AUC) = 0.93, 95CI 0.90-0.96) and fracture (AUC = 0.67, 95% CI 0.58-0.75). Linear discriminant analysis (LDA) further showed that 88.9% of osteoporosis and 68.4% of fractures were correctly classified. Our study develops nomograms that may be used to predict cadmium-induced osteoporosis or fracture if BMD data is not available.Copper is often used as a growth promoter, at the same time copper is one of the most important essential trace elements for fur animals, especially Rex rabbits. However, too much copper added to the diet may harm animal health, and copper excreted in feces can pollute the environment. In this study, 3-month-old Rex rabbits were randomly divided into four groups and fed a basal diet containing 0, 30, 60, or 120 mg/kg Cu for 5 weeks. The diet supplemented with 30 mg/kg Cu significantly increased (P less then 0.05) the average daily feed intake (ADFI) and the average daily gain (ADG) and also the activity of serum Cu-Zn (zinc) superoxide dismutase and the digestibility of ether extract. Supplemental Cu up to 120 mg/kg did not significantly adversely affect the Zn metabolism of growing Rex rabbits. Overall, the data in this study indicate that 30 mg/kg is the optimal level of Cu supplementation in the diet of growing Rex rabbits. The results will provide a reference to improve the breeding of Rex rabbits and possibly other animals. In follow-up studies, the amount of copper in the diet should be reduced as much as possible from the baseline of 30 mg/kg copper.This study aimed to observe the influence of selenium (Se) deficiency on sperm quality and selenoprotein expression in rats. Four-week male Wista rats were randomly divided into three groups Se-A, Se-L, and Se-D (respectively for Se- adequate, low, and deficient group). After 9 weeks, the rats were sacrificed by anesthesia, with the cauda epididymidis quickly fetched for sperm count, motility, and deformity. Meanwhile the blood, liver, brain, heart, and testis were collected for Se and biochemical analysis. It was found that the rats in Se-D had poor growth, while the Se concentrations in blood, liver, and heart for Se-D decreased significantly, compared with Se-A and Se-L (p less then 0.01). But no significant difference was observed in testis and brain and also no statistical significance for sperm count. The sperm motility for Se-A (63.07%) was significantly higher than Se-L (53.91%) and Se-D (54.15%). Deformities were observed in both Se-L and Se-D. Both glutathione peroxidases (GPxs) and selenoprotein-P (SEPP1) levels in plasma and tissues of Se-D were significantly lower than those of Se-A and Se-L (p less then 0.
My Website: https://www.selleckchem.com/products/diphenyleneiodonium-chloride-dpi.html
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