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bronchial dilations (BDs) seem to have a major role in the natural history of chronic obstructive pulmonary disease (COPD). The purpose of our study was to evaluate the impact of BDs on the severity and progression of COPD as well as on patients' prognosis.
we conducted a retrospective, single-center, analytical study over the period 1995- 2017. The study was based on data from the medical records of patients with COPD who had undergone chest CT scan during the follow-up period. We compared two groups (G) of patients G1 COPD with BDs; G2 COPD without BDs.
our study included 466 patients with COPD. Among them 101 (21.6%) had BDs associated with COPD. G1 patients had lower maximum expiratory volume in the first second (FEV1) (G1 1.21 L, G2 1.37 L, p = 0.015), lower forced vital capacity (FVC) (p = 0.014), a lower PaO2 at steady state (p = 0.049), a higher rate of acute exacerbations (AE) per year (G1 3.31, G2 2.44, p = 0.001) and a higher rate of hospitalizations in the Intensive Care Unit per year (p = 0.02). G1 patients with AE receiving treatment in hospital had lower PaO2 3) on admission (G1 60 mmHg, G2 63.7 mmHg, p = 0.02 G2 63.7 mmHg, p = 0.023), more elevated carbon dioxide (CO2) levels (p = 0.001) and were characterized by a higher use of non-invasive ventilation (NIV) (p = 0.044) and invasive mechanical ventilation (p = 0.011). G2 patients had better overall survival (p = 0.002).
bronchial dilatations are an indicator of poor prognosis in patients with chronic obstructive pulmonary disease, expecially because of the higher rate and severity of exacerbations, airway obstructions and mortality.
bronchial dilatations are an indicator of poor prognosis in patients with chronic obstructive pulmonary disease, expecially because of the higher rate and severity of exacerbations, airway obstructions and mortality.
the COVID-19 pandemic has necessitated many public health preventive measures including lockdowns or curfews. However, because humans are used to working and moving up and down, they would need to find ways to avert the negatives associated with the COVID-19 induced lockdown. Therefore, the purpose of this study was to qualitatively explore experiences of Ghanaians during the lockdown period in terms of physical activity, dietary behaviors, boredom, and changes in weight.
using a phenomenological approach, we analyzed data from 27 persons from Accra, Tema, and Kumasi who filled our online open-ended survey. We created open-ended items and circulated online (between 21
April, 2020 and 10
May, 2020) to persons who experienced the lockdown. We analyzed the data using Colaizzi´s 7-step phenomenological approach.
many people felt very bored and frustrated during the lockdown period, and some of these people resorted to physical exercise routines either individually or collectively as family. However, many experienced tremendous physical inactivity because of lack of space. They experienced poor eating behaviors, all of which resulted in reported weight gains.
the COVID-19 pandemic lockdown has caused boredom and frustrations to quite a number of people. Physical inactivity increased because of lack of space, coupled with poor eating habits producing high levels of weight gain among people who experienced the lockdown in Ghana. There is therefore an urgent need to teach these people how to exercise within limited space and how to eat healthily during times of restriction.
the COVID-19 pandemic lockdown has caused boredom and frustrations to quite a number of people. Physical inactivity increased because of lack of space, coupled with poor eating habits producing high levels of weight gain among people who experienced the lockdown in Ghana. There is therefore an urgent need to teach these people how to exercise within limited space and how to eat healthily during times of restriction.
South Africa adopted and implemented the Universal Test and Treat (UTT) strategy for HIV since 2016. However, the care outcomes for patients initiated antiretroviral therapy (ART) through the UTT strategy have not been established. We determined the rate of lost to follow up (LTFU) and associated factors in patients who were initiated on ART through the UTT and the pre-ART strategy at 12 months post ART initiation.
this retrospective study analyzed the records of a cohort of patients at 12 months post the initiation of ART. We extracted data from the TIER.Net electronic database of selected facilities in a sub-district in Gauteng Province, South Africa. Factors associated with LFTU at 12 months of ART were assessed and logistic regression performed to identify predictors of LFTU.
records of 367 patients were evaluated, and 54% were initiated ART through the UTT strategy. The mean age was 36.3 years, mean CD4 cell count at ART initiation was 341 cells/mm
, and 25% were initiated at CD4 cell count above 500 cells/mm
. LTFU at 12 months was 28%, 50% were LFTU within six months, and 28% within three months of ART. LFTU in the UTT cohort was higher than in the pre-ART cohort, patients initiated through UTT were twice more likely to be LTFU (AOR = 1.84, CI 1.13-3.00) than pre-ART patients.
the rate of LTFU at 12 months of ART was 28%, which indicate that the retention in care rate (60%) falls far short of the triple 90 targets required for viral suppression.
the rate of LTFU at 12 months of ART was 28%, which indicate that the retention in care rate (60%) falls far short of the triple 90 targets required for viral suppression.
cholera is a significant public health concern among displaced populations. Oral cholera vaccines are safe and can effectively be used as an adjunct to prevent cholera in settings with limited access to water and sanitation. Results from this study can inform future consideration for cholera vaccination at Kakuma and Kalobeyei.
a descriptive cross-sectional study of cholera cases at Kakuma refugee camp and Kalobeyei integrated settlement was carried out between May 2017 to May 2018 (one year). Data were extracted from the medical records and line lists at the cholera treatment centres.
the results found 125 clinically suspected and confirmed cholera cases and one related death (CFR 0.8%). selleck inhibitor The cumulative incidence of all cases was 0.67 (95% CI=0.56-0.80) cases/1000 persons. Incidence of cholera was higher in children under the age of five 0.94(95% CI=0.63-1.36) cases/1000 persons. Children aged <5 years showed 51% increased risk of cholera compared to those aged ≥5 years (RR=1.51; 95% CI=1.00-2.31, p=0.
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