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Snooze Dimension inside Children-Are We on the right course?
. Endovascular surgery is another option in specific cases.
The Oswestry Disability Index (ODI) is one of the most common patient-reported outcome measures used for low back pain (LBP). AZD5069 Since it was not available in Indonesian, this study aimed to perform a cross-cultural adaptation of ODI to Indonesian and evaluate its psychometric properties.

We performed a cross-cultural adaptation of ODI v2.1a into Indonesian language (ODI-ID) and determined its internal consistency, test-retest reliability, measurement error, confirmatory factor analysis, floor-ceiling effect, and construct validity by hypotheses testing of its correlation with Short Form-36 (SF-36) and visual analog scale (VAS). Adults (> 17years of age) diagnosed with low back pain were included.

A total of 96 subjects were included in this study. The original ODI questionnaire was translated into an Indonesian version and showed a good internal consistency (Cronbach's alpha = 0.90) and good reliability (intraclass correlation = 0.97). The standard error of measurement values of 3.35 resulted in a minimal detectable change score of 9. Nine out of nine (100%) a priori hypotheses were met, confirming the construct validity. A strong correlation was found with the physical component of SF-36 (0.77 and 0.76 for pain and physical function, respectively) and VAS (0.79). Confirmatory factor analysis resulted in a poor but significant fit to the original one-factor structure and the static-dynamic two-factor structure. Floor-ceiling effects were not found.

The Indonesian version of ODI displayed similar reliability, validity, and psychometric characteristics to the original ODI. This questionnaire will be a suitable instrument for assessing LBP-related disability for Indonesian-speaking patients.
The Indonesian version of ODI displayed similar reliability, validity, and psychometric characteristics to the original ODI. This questionnaire will be a suitable instrument for assessing LBP-related disability for Indonesian-speaking patients.The aim of this study was to develop prediction equations for the body weight of Pelibuey ewes from body measurements comparing linear vs nonlinear models. A subsample of 197 ewes was scored for body weight (BW), rump length (RL), rump width (RW), height at withers (HW), chest girth (CG), chest width (CW), chest depth (CD), cannon bone perimeter (CP), and body length (BL). Pearson's correlation analysis was performed on a sub-data set from 197 ewes to estimate the relationship between body weight and body measurements. Multiple linear regressions were fitted to obtain prediction equations of body weight from the eight body measurements, and prediction equations were obtained from the body measurement that showed the highest correlation with body weight using five nonlinear models allometric, saturation growth, exponential, and incomplete gamma. Data from an independent subsample of 196 ewes was used to validate the equation with the best goodness of fit using linear regression analysis. CG was the body measurement that showed the highest correlation with BW, and based on multiple stepwise regression, in the equation BW = - 60.622 + 1.233CG explained 79% of the body weight variation. Moreover, BW prediction was more accurate when other measurements such CW, BL, and RW were added to the model generating to the equation BW = - 68.875 + 0.845CG + 0.866CW + 0.195BL + 0.601RW (R2 = 0.85, MSE = 15.51). In the case of nonlinear models, incomplete gamma and exponential models generated the equations with the best goodness of fit and precision BW = 0.077CG1.108exp(0.016CG) (R2 = 0.82, MSE = 18.64) and BW = 3.5759exp(0.0292CG) (R2 = 0.82, MSE = 18.65) respectively.In this study, the novel high-speed tablet film coating process in the continuous manufacturing was investigated. The influence of key process variables (inlet air flow rate, inlet air temperature, and suspension spray rate) were investigated using a Box-Behnken experimental design method. Statistical regression models were developed to predict the outlet air temperature and relative humidity, the coating efficiency, the tablet moisture content, and coating uniformity. The effects of the three key process variables were comprehensively investigated based on mathematical analysis, contour plots, and interaction plots. The results indicate that all the process responses are affected by changing the inlet air flow rate, temperature, and suspension spray rate. A design space (DS) in terms of failure probability was determined based on specifications for tablet moisture content ( less then  3.5%) and coating uniformity (tablet weight standard deviation less then  4 mg for tablet weight of 200 mg) using Monte Carlo simulations. Independent experiments were carried out and successfully validated the robustness and accuracy of the determined DS for the investigated tablet film coating process. All the data were generated using an industrial pilot-scale novel high-speed tablet coating unit from a continuous manufacturing line. The work facilitates the quality by design implementation of continuous pharmaceutical manufacturing.
Prior studies have focused only on the temporal component of one-leg standing, no reports have examined the relationship between the qualitative components of one-leg standing and femoral BMD. Thus, this study investigated whether quality (i.e., movement control) of one-leg standing also associated femoral BMD.

A total of 80 patients with unilateral hip fracture were included in a cross-sectional study. Basic and medical information and physical functions including movement control during one-leg standing were assessed at admission and 2weeks after surgery, respectively. Hierarchical multiple regression analysis was performed to identify predictors of femoral BMDs on the non-fractured side. Dependent variables included femoral neck and total hip BMDs in models 1 and 2, respectively.

Hierarchical multiple regression analysis (standardized partial regression coefficients) in model 1 identified age (- 0.18), sex (0.38), body mass index (BMI) (0.41), movement control during one-leg standing on the non-fractured side (0.
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