Notes

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In terms of age and gender distribution of ADRs, there were 10 males (55.56%) and 7 females (44.44%), and ADRs were more common in patients aged 46-60 years old (total of 6 ADRs, 35.29%). Aidi injection mainly induced mild ADRs (total of 22 ADRs, 73.33%), and the resulting ADRs mostly occurred for <2 hours (total of 19 ADRs, 60.00%). After the specific nursing interventions were performed, no deaths due to ADRs occurred, and 12 (64.71%) cases were cured, 5 (29.41%) cases improved, and 1 (5.88%) case had no progression.

Particular attention should be paid to ADRs in the treatment of NHL patients with Aidi injection. After ADRs occur, specific nursing interventions can aid in recovery and lead to improvements in prognosis.
Particular attention should be paid to ADRs in the treatment of NHL patients with Aidi injection. After ADRs occur, specific nursing interventions can aid in recovery and lead to improvements in prognosis.
Prophylactic pancreatic stent placement (PSP) and rectal indomethacin suppository are recommended to prevent post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) in high-risk cases. Clinical trials on the use of nitroglycerin to reduce PEP have reached no definitive conclusion. Our study aimed to determine whether treatment with rectal indomethacin plus nitroglycerin could eliminate the need for PSP in patients.

In this randomized clinical trial, patients were allocated into groups using a random number table, with each patient receiving a pre-made envelope containing their intervention prior to ERCP. The three treatment groups were the placebo group, the indomethacin + nitroglycerin group, and the PSP group. The subjects were assessed for PEP and its severity by a panel of independent and blinded adjudicators.

A total of 526 patients were eligible for inclusion. The placebo group included 176 patients, the indomethacin + nitroglycerin group included 176 patients and the PSP group included 174.A diagnosis of PEP was made in 64 (12.2%) cases. The rate of PEP in the three study groups placebo group, indomethacin + nitroglycerin group and the PSP group was 19.3%, 5.1%, and 12.1%, respectively.

The risk of post-ERCP pancreatitis in the indomethacin + nitroglycerin group was 7% lower than that in the PSP. Indomethacin + nitroglycerin is superior to PSP in preventing and relieving the severity of post-ERCP pancreatitis in patients with difficult intubation. Indomethacin plus nitroglycerin can avoid the need for PSP in the prevention of post-ERCP pancreatitis.

Current Controlled Trials ChiCTR2000033944.
Current Controlled Trials ChiCTR2000033944.
Supraclavicular brachial plexus block (SCBPB) is a traditional anesthesia technique widely used in upper limb surgery. Ultrasound-guided SCBPB shows the peripheral structure and dynamic local anesthetic diffusion and can greatly shorten the anesthesia operation time, increase the success rate of anesthesia, and reduce the incidence of complications. However, it can still block the phrenic nerve and paralyze the diaphragm, which can be difficult to avoid. This study investigated two different volumes of the same concentration of ropivacaine used in ultrasound-guided SCBPB, and compared the effects on the incidence of diaphragmatic paralysis, pulse oxygen saturation (SpO2) and lung function in patients.

The study group comprised 103 patients who were to undergo surgery on the right forearm or right hand. They were randomly divided into two groups group A were given 20 mL 0.375% ropivacaine, and group B were given 30 mL 0.375% ropivacaine. We recorded the SpO2, forced vital capacity (FVC), and forced expirat30 mL of 0.375% ropivacaine can achieve the ideal brachial plexus block with ultrasound-guided SCBPB, but compared with 20 mL of 0.375% ropivacaine, 30 mL of 0.375% ropivacaine is more likely to cause diaphragmatic paralysis.
To explore the relationship between CD177 and the vasculogenic mimicry (VM), clinicopathological parameters, and prognosis of epithelial ovarian cancer.

Tumor tissue samples and clinicopathological data were collected from 98 patients with epithelial ovarian cancer. The expression of CD177 in tumor tissues was detected by immunohistochemical streptavidin-peroxidase conjugate (SP) method, while the VM structure in tumor tissues was identified by CD31/periodic acid-Schiff (PAS) double staining in order to analyze the relationship between CD177, VM, clinicopathological parameters, and the prognosis of epithelial ovarian cancer.

The proportion of the positive expression of CD177 (CD177+) in 98 ovarian cancer tissues was higher than that of the negative expression of CD177 (CD177-) (65.31% vs. ISX-9 in vivo 34.69%, P<0.05). Univariate analysis showed that CD177+ was associated with VM formation, tumor differentiation degree, tumor diameter, tumor stages, and platinum sensitivity (P<0.05), and was not associated with age, tumor types, or lymph node metastasis (P>0.05). Correlation analysis showed that CD177+ was positively correlated with VM formation, tumor differentiation degree, tumor diameter, and tumor stages (P<0.05), and was negatively correlated with platinum sensitivity (P<0.05). Kaplan-Meier survival analysis showed that the survival time of CD177+ patients was significantly shorter than that of CD177- patients (P<0.05).

CD177+ is associated with the tumor malignancy of patients with epithelial ovarian cancer, and may participate in the formation of VM structure in epithelial ovarian cancer tissues. It can thus serve as important indicator for the prognosis of patients.
CD177+ is associated with the tumor malignancy of patients with epithelial ovarian cancer, and may participate in the formation of VM structure in epithelial ovarian cancer tissues. It can thus serve as important indicator for the prognosis of patients.
Venous thromboembolism (VTE) is a serious health problem for which pharmacological prophylaxis has been proven to be effective. However, there are significant gaps between the guidelines and clinical practice. This study is to evaluate the effect of physician educational intervention (PEI) on VTE pharmacological prophylaxis in medical inpatients from the respiratory department.

Medical inpatients from the respiratory department between February 2014 and December 2016 were recruited in this retrospective cohort study. They were assigned to the PEI group or the control group according to whether their physicians undertook a quality improvement (QI) project carried out in hospital to raise physician awareness of pharmacological thromboprophylaxis by educational intervention. Any and appropriate pharmacological VTE prophylaxis rates, the use of appropriate anticoagulants, and the occurrence of VTE events in the two groups were calculated and compared using a chi-square test and continuity correction. Poisson regression analysis was used to evaluate the relative risk (RR) of PEI on the occurrence of VTE events.
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