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Management of Agonizing Person suffering from diabetes Neuropathy-A Narrative Review of Medicinal along with Interventional Approaches.
Specifically, infrastructure has the most important impact on waste separation behavior, followed by information and then perceived cost. Third, the perceived cost is significantly negatively related to WSB, and perceived benefit has a positive effect but is statistically insignificant. It has a practical implication for the government. Providing sufficient infrastructure and launching effective information activities could improve the perceived benefit including biospheric, egoistic, social-altruistic, and reputation; and reduce the perceived cost of time, physical, learning, and money, which could then induce rural households to engage in WSB.The paper presents sorption behavior of Arachis hypogaea shells towards silver ions and possibility of their use as antimicrobial product. During the modification process of the natural sorbent, equilibrium tests were carried out. Moreover, the possibility of obtaining biocomposite Arachis hypogaea shells/nAg has been determined, and its antimicrobial properties have been evaluated. Additionally, sorption kinetics has been calculated. In the last step, silver ions were desorbed. The conducted equilibrium tests allowed to adjust the sorption isotherm model and determine the sorption capacity of tested material. This process is best described by Freudlich's isotherm, and the sorption capacity is equal to 12.33 mg/g. On the basis of kinetic studies, the chemical nature of this process has been proved (by choosing a pseudo-second order model for the sorption process). It has been confirmed that the obtained peanut shells modified with silver ions have antimicrobial properties. The tests allowed to obtain 100% inhibition of Aspergillus niger and ~ 98% Escherichia coli.As an important indicator of greenhouse gas emissions, the carbon footprint (CF) has become increasingly important in recent years under the dual pressures of global warming and international commitments to mitigate its effects. Doxorubicin ic50 This study collected 3698 papers related to CF from the Web of Science database as research samples (year 2007 to 2018). Based on CiteSpace, the knowledge base, popular topics, and research trends of CF are presented. The results show the following (1) from 2007 to 2018, the number of articles on CF have steadily increased. (2) After spatial analysis of the literature, we found that among research institutions, the Chinese Academy of Sciences has the largest number of publications on the issue. When it comes to country, three important research forces can be identified USA, China, and UK. (3) Research on the CF is interdisciplinary; in addition to the traditional fields of environmental, political, economics, and computing, CF research has received attention from the Physics, Materials, Chemistry, Mathematics, and animal sciences. (4) Through keyword clustering, currently popular topics in research can be roughly divided into four aspects CF calculation methods, research scales, energy, and agriculture. (5) The CF research during the study period is divided into four stages according to the burst time and content of the burst keywords. According to the research status and trend, this paper puts forward the future research direction of carbon footprint.A road traffic accident is a burning issue because the cost of road accidents is about 2% of gross domestic product in Pakistan. This paper explores the relationship between health force density index, temperature, rainfall, road lengths, and road traffic fatalities in Pakistan from 1985 to 2016. The stationarity was determined with the help of four-unit root tests. The existence of long-run cointegration was determined by using the autoregressive distributing lag bound test. The vector error correction model showed the long-run causality of road traffic fatalities, which implies that road traffic fatalities were affected by selected variables in the long-run. The short-run unidirectional causality was running from road traffic fatalities to health force density index; temperature to health force density index; rainfall to health force density index; health force density index to rainfall; road traffic fatalities to high type road length; health force density index to high type road length; and temperature tofic law enforcement. It is difficult for the Pakistani government to effectively execute road safety plans due to the limitation of resources. However, the government should invest the revenue collected through tax violation fine for the improvement in road safety. It is also needed to invest in the health sector and up-gradation of the hospitals for the safety of human beings. The government should ensure the availability of the latest medical technology in the hospitals and the improvement of emergency services. It is required to develop coordination between various ministries such as transportation, planning, law, education, public health, and information. It is necessary to make the public aware of the social and economic cost of road accidents using electronic, print, and social media. Graphical abstract.In the present study, an application of cellulose nanofibers has been established for the controlled release of an anticancer drug, i.e., camptothecin. The camptothecin is known for its antitumor activity. However, it has certain limitations like instability, low solubility in aqueous solution, and biological fluids. Firstly, the camptothecin was encapsulated into the cellulose nanofiber complex by adjusting the composition ratio of cellulose nanofibers-camptothecin, i.e., 103, 105, and 107. In the 103 composition ratio of cellulose nanofibers, camptothecin showed the highest encapsulation efficiency, i.e., 65.28%. The binding of camptothecin with cellulose nanofibers was confirmed by FT-IR analysis. Also, the Langmuir, Freundlich, Temkin, and Dubinin-Radushkevich isotherm studies demonstrate physical adsorption of camptothecin onto the homogeneous as well as the heterogeneous surface of cellulose nanofibers. Further, the controlled and extended-release profile was observed at different physiological pH, and different kinetics models were used to understand the drug release mechanism. The highest correlation in all pH conditions was obtained in Korsmeyer-Peppas with R2 value = 0.93 (pH 1.2), 0.89 (pH 6.8), and 0.97 (pH 7.4), whereas in Higuchi model, R2 value = 0.89 (pH 1.2), 0.91 (pH 6.8), and 0.98 (pH 7.4), suggesting the release of a drug via a diffusion mechanism. Hence, the results established that enzyme-mediated cellulose nanofibers may also be an optimal carrier for the controlled drug release formulation without any chemical excipients.
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