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ADHD Stimulant Medication
Stimulants help people with ADHD manage their focus and impulsive behavior. They can be short- or long-acting and are prescribed by psychiatrists, paediatricians or neurologists (and GPs in some circumstances).
Stimulants affect norepinephrine and dopamine in the brain. They are tightly controlled and are only prescribed by a physician.
Methylphenidate
Methylphenidate belongs to the stimulant family and increases brain activity. It increases the levels of certain chemicals, such as noradrenaline and dopamine, which helps to regulate attention and behavior. Methylphenidate is used to treat ADHD and narcolepsy. It can also be prescribed to treat depression in adults, but this is not endorsed by the Food and Drug Administration (FDA). Methylphenidate gets absorbed from the gut into the bloodstream quickly and works within hours. It is available as an immediate-release tablet or chewable extended-release capsule or tablet. The doctor will prescribe the most suitable formulation based on the person's symptoms and the possibility of side effects.
The side effects of methylphenidate tend to be mild and go disappear over time as the body gets used to the drug. Speak to adhd medication and pregnancy should you experience any issues. He can lower the dosage or try another medication. It is essential to take this medication exactly as prescribed and not exceed the recommended dose. This reduces the risk for addiction or abuse. Methylphenidate is classified as a Schedule II drug by the US Drug Enforcement Administration, which means it has a significant risk of abuse. These stimulants could create dependence and withdrawal if not taken in the prescribed manner.
It is essential to inform the doctor that your child is suffering from heart problems, such as an irregular heartbeat or history of a heart attack. Methylphenidate can raise heart rate, which is why the doctor will examine their heart rhythm and blood pressure before they start treatment. It's also important to tell the doctor if your child is taking any other medications, like herbal remedies, vitamins or supplements.
The doctor will tell you how much medication to take and how often, as well any other precautions. Methylphenidate is best taken twice a day with meals. Certain brands of the long-acting methylphenidate chewable tablets (Quillichew ER, Cotempla XR-ODT and Adhansia XR) contain aspartame which is a source of phenylalanine. It should not be consumed by people with Phenylketonuria (an inherited condition that requires a low-protein diet to prevent severe intellectual impairment).
It is important to stay clear of alcohol and other drugs while taking this medication. Some people might notice their appetite declines when they take methylphenidate. Encourage your child to consume regular meals and snacks if they are losing weight. You may need to encourage them to drink a lot of squash or water to ensure they are hydrated.
Lisdexamfetamine
Lisdexamfetamine is a central nerve system stimulant, sold under the brand name Vyvanse. It affects chemicals in the brain and nerves. It improves concentration and control of impulses in adolescents, children and adults with ADHD. It treats binge-eating disorder (BED) as well as increasing the levels of dopamine and norepinephrine in the brain. This reduces uncontrolled eating.
Lisdexamfetamine is one of the prodrug class of medications, which are modified to make them inactive until they are metabolized the body.27 It has been shown to be safe and well-tolerated by a variety of placebo-controlled studies and has shown efficacy for both stimulant-naive and stimulant-exposed patients with ADHD. It is also thought to provide a longer-lasting effect than other stimulants and could have fewer rebound symptoms.
Adler et al27 reported that the scores for ADHD-RS-IV improved significantly in a 12-week controlled study. They also found that the majority of those who were switched to placebo relapsed after two weeks.28 Additionally, Brams et al29 used a novel design for a randomized withdrawal study in which they followed 116 adult patients for 12 weeks after stopping treatment with lisdexamfetamine. They discovered that the majority of patients who relapsed were not exposed to any other stimulants during the previous two weeks.
It is crucial to inform your doctor if you suffer from any allergies to this medicine or any other medications. Inform your doctor if suffer from high blood pressure, heart issues or other heart-related conditions. These stimulants increase the risk of heart attacks, or sudden deaths in people with these conditions.
Lisdexamfetamine can be absorbed into breastmilk and cause harm to a nursing infant. It is not recommended to breastfeed while taking this medication. This medication can cause shakiness, dizziness, or stomach upset in some individuals. Lisdexamfetamine is not suitable for use by children less than six years old. Lisdexamfetamine is not recommended for women who are pregnant or nursing. It is not recommended to stop taking this medication unless your doctor tells you to stop even if you are feeling better. While you are taking this medication the doctor will monitor your blood pressure and pulse rate.
Atomoxetine
Atomoxetine (Strattera) is a nonstimulant that acts by blocking the presynaptic norepinephrine-transporter. It has a high affinity this transporter, with a minimal affinity for other neurotransmitter receptors and transporters [115,136]. In multiple placebo-controlled studies, it helped improve inhibitory control in ADHD patients by inhibiting overactivation of the right inferior frontal cortex (Chamberlain et al., 2009). It was also shown to increase working memory and attention span in children suffering from ADHD. It has a slow onset of action and can take up to 12 weeks for its full effect to be observed. The dosage is determined by weight and should be gradually increased. A daily dose of once is common. People who are not metabolizers of the drug Cytochrome P450 2D6 (CYP2D6) have greater exposure and slower elimination of atomoxetine. it is recommended to conduct a pharmacogenetic test prior to prescribing atomoxetine for these people.
In several controlled studies it has been demonstrated that it can be effective in reducing symptoms of ADHD. It is often employed as the first-line treatment. It is generally safe and well tolerated and does not increase the risk of suicidal behaviour. It is not as efficient as stimulants in reducing anxiety and tics and does not appear to help with sleep issues, but it has been proven to help with aggression in some children. Atomoxetine is also more likely to interact with antidepressant fluoxetine. Therefore, they should not be taken together [115, 137).
Clonidine (Catapres) and Guanfacine are two additional medications that are available as first-line treatments for ADHD. These medications were originally designed to lower high blood pressure in adults. These are alpha agonists. They operate by stimulating receptors within the mind to release neurotransmitters called norepinephrine, which can reduce the impulsivity and hyperactivity. These medications take a while to show results and it could take up to four weeks for many children before they see any benefits. They are not recommended for use with MAOIs(e.g. e.g. Phenelzine is not recommended due to the possibility of serious and potentially fatal adverse reactions, including severe hypothermia and rigidity myoclonus, and autonomic instability.
Other Stimulants
Stimulants are drugs which increase activity in the nervous system. They include a variety of drugs, some of them legal, while others are illicit. They are used for a number of reasons, including performance improvement, to stay alert and alert and to treat certain medical conditions like ADHD, depression, and narcolepsy. Amphetamines and methylphenidate as well as other prescription stimulants can be utilized. The term stimulant can also apply to nonprescription drugs like caffeine and certain diet pills that are used for a variety of reasons but may not be safe when taken together with other medications or some foods.
Stimulants don't cause habit-forming doses prescribed for people with ADHD however, they do have side effects. Some patients may feel jittery or shakey. They can raise blood pressure and heart rate, cause an upset stomach and may cause sleep problems.
Children and teens who take stimulants may experience tics or repeated sounds or movements, such as eye blinking or throat clearing. They may also experience a minor growth delay.
A doctor will determine the right stimulant for you or your children. They will also take into consideration factors such as weight and age as well as allergies. The doctor will then prescribe medications. Always follow the directions of your doctor. You should always go through the Medication Guide that is included with your prescription.
The use of medication isn't the only option to reduce symptoms of ADHD However, they're typically the first treatment option. Psychosocial interventions such as family therapy and behavior modification are also available to assist people of all ages with ADHD.
People who are prescribed ADHD medication should be screened for the possibility of misuse and abuse evaluated, and be counseled not to give their medication to others. They should also be encouraged to keep their medication locked away and properly destroyed. Health professionals must also regularly examine patients for indications of abuse, misuse, or addiction. The FDA has mandated that more consistent information be included on the labeling of drugs to help educate families and patients about the serious risks.
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