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Poor standing posture has been reported in women with larger breasts, increasing the risk of back pain. Whilst breast reduction surgery can improve posture, conservative measures such as special bras may offer short or long-term relief of symptoms without surgical intervention.
This study aimed to utilise a multi-study intervention to investigate the short and long-term kinematic effects of wearing a posture bra.
Study one utilised biomechanics and physiotherapy expertise to modify the design of a prototype bra to improve posture and breast kinematics; resulting in a second-generation posture bra. To test this bra, 24 females were randomly assigned to control and intervention groups. The control group wore their everyday bra; the intervention group wore the generation 2 posture bra in place of their everyday bra for three months. Pre and post intervention, posture (spine curvature, scapula position, whole body alignment) and breast kinematics were assessed during sitting, standing and walking. Short-terffectively support the breasts and improve scapula position without compromising spinal curvature, reducing the risk of musculoskeletal pain associated with poor posture.
Inertial measurement units (IMUs) are promising tools for collecting human movement data. Model-based filtering approaches (e.g. Extended Kalman Filter) have been proposed to estimate joint angles from IMUs data but little is known about the potential of data-driven approaches.
Can deep learning models accurately predict lower limb joint angles from IMU data during gait?
Lower-limb kinematic data were simultaneously measured with a marker-based motion capture system and running leggings with 5 integrated IMUs measuring acceleration and angular velocity at the pelvis, thighs and tibias. Data acquisition was performed on 27 participants (26.5 (3.9) years, 1.75 (0.07) m, 68.3 (10.0) kg) while walking at 4 and 6km/h and running at 8, 10, 12 and 14 km/h on a treadmill. The model input consists of raw IMU data, while the output estimates the joint angles of the lower body. The model was trained with a nested k-fold cross-validation and tested considering a user-independent approach. Mean error (ME), mean absoistics of the wearer, or the position and orientation of the IMU relative to the attached segment. These results have been validated with treadmill gait, and have not yet been confirmed for gait in other settings.Accurate estimation of plant water status is a major factor in the decision-making process regarding general land use, crop water management and drought assessment. Visible-near infrared (VNIR) spectroscopy can provide an effective means for real-time and non-invasive monitoring of leaf water content (LWC) in crop plants. The current study aims to identify water absorption bands, indices and multivariate models for development of non-destructive water-deficit stress phenotyping protocols using VNIR spectroscopy and LWC estimated from 10 different rice genotypes. Existing spectral indices and band depths at water absorption regions were evaluated for LWC estimation. The developed models were found efficient in predicting LWC of the samples kept in the same environment with the ratio of performance to deviation (RPD) values varying from 1.49 to 3.05 and 1.66 to 2.63 for indices and band depths, respectively during validation. For identification of novel indices, ratio spectral indices (RSI) and normalised difference spectral indices (NDSI) were calculated in every possible band combination and correlated with LWC. The best spectral indices for estimating LWC of rice were RSI (R1830, R1834) and NDSI (R1830, R1834) with R2 greater than 0.90 during training and validation, respectively. Among the multivariate models, partial least squares regression (PLSR) provided the best results for prediction of LWC (RPD = 6.33 and 4.06 for training and validation, respectively). The approach developed in this study will also be helpful for high-throughput water-deficit stress phenotyping of other crops.In this study, sensitive detection of lamotrigine in human plasma samples was realized at a low cost approach through ultrasound-assisted emulsification-microextraction based on using a hydrophobic deep eutectic solvent followed by back-extraction (USAEME-DES-BE) method. After extraction, detection and quantification of lamotrigine were done by spectrophotometry in the UV region. The hydrophobicity of the deep eutectic solvent not only eliminates the need of the third solvent as an emulsifying agent but also helps to retrieve lamotrigine from the DES by back-extraction to another aqueous phase. The back extraction process allowed the drug to be measured in the UV region. Central composite design in combination with a desirability function approach was applied for the optimization of the USAEME-DES-BE procedure. Essential factors in the method efficiency were discussed, such as back-extraction solution, time of back-extraction, the ratio of DES components, pH, the volume of DES, salt concentration, and sonication time. The method exhibited a wide dynamic linear range from 0.5 to 10 µg mL-1 and a limit of detection of 0.15 μg mL-1. The established method was successfully applied to determine lamotrigine in human plasma samples with satisfactory relative recoveries.Sulfur quantum dots (SQDs), heavy-metal-free quantum dots, are regarded as the next generation promising green nanomaterials compared with traditional heavy-metal-based quantum dots. However, there have been few reports on the synthesis and application of SQDs for analytical detection. Herein, an H2O2-assisted top-down method is used to synthesize SQDs. ITF3756 research buy The as-obtained SQDs have good water dispersion, stability, photoluminescence (PL) properties and achieving a quantum yield (QY) to 11%. After adding Cr (VI) in SQDs, the fluorescence intensity decreases base on inner filter effect (IFE). Moreover, Cr (VI) can be reduced to Cr(III) when ascorbic acid (AA) is introduced into the SQDs - Cr (VI) system, accompanying the recovery of the fluorescence intensity. The fluorescence sensor displays high sensitivity and quickly response toward Cr (VI) and AA in a range of 10-120 μmol L-1 and 20-500 μmol L-1 with a detection limit of 0.36 μmol L-1 and 1.21 μmol L-1, respectively. In addition, the fluorescence sensor has been applied for the determination of Cr (VI) and AA in real samples.
Homepage: https://www.selleckchem.com/products/itf3756.html
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