Notes

Activation in people together with emotional wellbeing disorders: A great integrative assessment.
ys and their cross talk to combat this virus in precarious settings is our future positive hope.International Guidelines have voted for PCR as the Gold Standard in COVID diagnosis. Nasoparyngeal swab is the preferred specimen for PCR. It has a high probability of diagnosing early infection. But the diagnostic sensitivity of nasopharyngeal PCR decreases with increase in lapse between the infection and presentation to hospital. This might lead to dire consequences of labelling these patients as false negative, though such patients have been proved to be potentially infective since viral shedding occurs through other body fluids (stools) for long. COVID infection reveals that the IgM antibodies start to appear as early as 5th day of infection and switches over to IgA within 2-3 days. The aim of the study was to see if COVID antibody testing be coupled with PCR for diagnosis especially in patients presenting late (more than 14 days) of onset of infection? And if the antibodies are giving values, hence can them be reported quantitatively rather than in qualitative fashion? The second objective was to see if the COVID antibody levels be used to monitor the disease severity? And if the antibody levels of SARS CoV 2 be used an indicator to monitor the recovery?Hydrogels are attractive due to their various applications in the fields of biomedical materials, cosmetics, and biosensors. To enhance UV protection and prevent skin penetration behaviors, inspired by the mussel adhesive proteins, the functional polydopamine (PDA) is employed herein to fabricate polydopamine/carboxymethyl cellulose/polyacrylic acid (PDA/CMC/PAA) adhesive hydrogels. To disperse PDA nanoparticles well in the PAA matrix, dopamine was self-polymerized in CMC solution to form PDA/CMC complex. Acrylic acid was polymerized in PDA/CMC complex solution and cross-linked to construct UV-resistant PDA/CMC/PAA hydrogel. The morphology, rheological behavior, mechanical properties and adhesion strength of PDA/CMC/PAA hydrogels were studied by scanning electron microscopy, rotational rheometer, universal test machine. Owing to the hydrogen bonding interaction between the PDA/CMC complex and PAA, the PDA/CMC/PAA hydrogels showed high resilience and compressive strength to withstand large deformation. The hydrogels exhibited strong adhesion to various substrate surfaces, such as stainless steel, aluminum, glass and porcine skin. The biocompatibility and UV-shielding properties were investigated through culture of cells and UV irradiation test. The adhesiveness of PDA promoted cell adhesion and provided the PDA/CMC/PAA hydrogels good biocompatibility with 96% of relative cell viability. The hydrogels possessed excellent UV-shielding ability to prevent collagen fibers from being destroyed during UV irradiation, which has promising potential in the practical applications for UV filtration membrane and skin care products.The oceans face a range of complex challenges for which the impacts on society are highly uncertain but mostly negative. Tackling these challenges is testing society's capacity to mobilise transformative action, engendering a sense of powerlessness. Envisaging positive but realistic visions of the future, and considering how current knowledge, resources, and technology could be used to achieve these futures, may lead to greater action to achieve sustainable transformations. Future Seas (www.FutureSeas2030.org) brought together researchers across career stages, Indigenous Peoples and environmental managers to develop scenarios for 12 challenges facing the oceans, leveraging interdisciplinary knowledge to improve society's capacity to purposefully shape the direction of marine social-ecological systems over the UN Decade of Ocean Science for Sustainable Development (2021-2030). We describe and reflect on Future Seas, providing guidance for co-developing scenarios in interdisciplinary teams tasked with exploring online version contains supplementary material available at (10.1007/s11160-020-09629-5) contains supplementary material, which is available to authorized users.The Susceptible-Exposed-Infected-Recovered (SEIR) epidemiological model is one of the standard models of disease spreading. Here we analyse an extended SEIR model that accounts for asymptomatic carriers, believed to play an important role in COVID-19 transmission. For this model we derive a number of analytic results for important quantities such as the peak number of infections, the time taken to reach the peak and the size of the final affected population. We also propose an accurate way of specifying initial conditions for the numerics (from insufficient data) using the fact that the early time exponential growth is well-described by the dominant eigenvector of the linearized equations. Secondly we explore the effect of different intervention strategies such as social distancing (SD) and testing-quarantining (TQ). The two intervention strategies (SD and TQ) try to reduce the disease reproductive number, R 0 , to a target value R 0 target less then 1 , but in distinct ways, which we implement in our model equations. We find that for the same R 0 target less then 1 , TQ is more efficient in controlling the pandemic than SD. However, for TQ to be effective, it has to be based on contact tracing and our study quantifies the required ratio of tests-per-day to the number of new cases-per-day. Our analysis shows that the largest eigenvalue of the linearised dynamics provides a simple understanding of the disease progression, both pre- and post- intervention, and explains observed data for many countries. We apply our results to the COVID data for India to obtain heuristic projections for the course of the pandemic, and note that the predictions strongly depend on the assumed fraction of asymptomatic carriers.The new coronavirus disease (COVID-19) has paralysed many sectors of human life, including economic, social-cultural and political processes. In the political arena, several countries have postponed elections due to the COVID-19 pandemic. Other countries, including Malawi, went ahead with their planned elections. Malawi held a presidential election at a time when the number of COVID-19 cases was increasing rapidly. In this paper, we assess the effect of the perceived risk of catching COVID-19 on willingness to vote in the Malawi presidential election that was held on 23 June 2020. Turn out in this election was ten percentage points lower than in the general elections that were held a year earlier. The paper draws on a nationally representative survey of adult Malawians (n = 1155). selleck compound In our main analysis, we use instrumental variables to account for potential endogeneity. We find that nearly two thirds of Malawians thought that they were likely to catch COVID-19 at some point. Notwithstanding the COVID-19 risk, 86% of the country's citizens were willing to vote.
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