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To investigate the association between self-reported hearing difficulties and occupational exposure to industrial dust in workers in southern Brazil.
This is a cross-sectional analytical study conducted with data from the National Health Survey (Pesquisa Nacional de Saúde, 2013). The dependent variable was self-reported hearing impairment, and the primary independent variable was occupational exposure to industrial dust. The covariables were sex, skin color, age in complete years, exposure to noise, and exposure to chemical substances. The variables of occupational exposure to noise and chemical substances were used as adjustment variables (confounding variables), and the analyses were stratified per state (Santa Catarina, Paraná, and Rio Grande do Sul) to verify the difference in magnitude results per region. For the crude and adjusted analysis, the odds ratio (OR) was used as a measure of association, estimated through the logistic regression analysis. The data were analyzed through the software Stata, version 14.
Regarding the main exposure, 10.1% of the sample (n = 490) reported being exposed to industrial dust in an occupational environment, while 7.0% reported hearing impairment. In the final analysis, workers exposed to industrial dust were 1.77 times more likely to report hearing impairment when compared to individuals not exposed to this agent.
There was an association between hearing impairment and exposure to industrial dust in workers in the southern region of Brazil.
There was an association between hearing impairment and exposure to industrial dust in workers in the southern region of Brazil.
The initial-fit provided by the hearing aid manufacturer's software is generally a display of measurement done in the ear simulators. The need for verification of hearing aid output and gain in the real ear using probe-microphone measurement to match the prescriptive target is highlighted. The objective of the study was to evaluate the difference in real-ear aided response (REAR), real-ear insertion gain (REIG), aided thresholds, articulation index (AI) and word recognition score (WRS) in quiet, with hearing aid programmed to NAL-NL1 first-fit and NAL-NL1 optimized-fit using the probe-microphone technique.
In a repeated measure experimental design, 11 participants with a mean age of 41.09 (SD=±9.95) years having moderate and moderately-severe sensorineural hearing loss were tested monaurally in two aided conditions, with a 16-channel hearing aid programmed for manufacturer's NAL-NL1 first-fit and optimized-fit to NAL-NL1 using probe-microphone verification. The REAR, REIG, aided threshold, articulation index and word recognition scores in quiet were obtained for both aided conditions.
The REAR, REIG, aided threshold, AI and WRS in quiet were significantly better with the NAL-NL1 optimized-fit compared to manufacturer's NAL-NL1 first-fit.
The optimized-fit yields better audibility and improved word recognition in quiet. This supports best practice guidelines of many professional organizations regarding the use of probe-microphone measurement as the "Gold standard" for verification of hearing aid fitting, thereby providing better satisfaction and quality of life to hearing aid users.
The optimized-fit yields better audibility and improved word recognition in quiet. This supports best practice guidelines of many professional organizations regarding the use of probe-microphone measurement as the "Gold standard" for verification of hearing aid fitting, thereby providing better satisfaction and quality of life to hearing aid users.
To characterize phonological processing of adolescents and to identify language skills and cognitive functions that influence their age group.
83 typical adolescents aged from 11 to 16 years of age participated in the research. Phonological awareness tests, rapid automatic naming, neuropsychological assessment and reading were used. Descriptive analysis and linear regression were carried out with a 5% significance level.
Regarding phonological processing, a lower performance was found in the phonemic segmentation task, longer times for object naming and performance as were expected for working memory of the age range. There was a reciprocal association between rapid naming of objects, letters and working memory, between rapid naming of letters and phonological awareness. Executive functions and attention influence working memory and phonological awareness. Semantic episodic verbal memory influenced working memory and reading, phonological awareness.
The performance in phonological processing was influenced by linguistic and cognitive skills which suggests they are still improving in adolescents.
The performance in phonological processing was influenced by linguistic and cognitive skills which suggests they are still improving in adolescents.The present study attempted to evaluate the practical experience and methods employed by Brazilian veterinary practitioners for control of parasites. Twenty-one questions were asked of 403 veterinary practitioners based in different climatic zones with reference to parasite epidemiology from the country. Administration of a combination of drugs at three-month intervals was the most common regime recommended for prophylaxis against gastrointestinal helminths, with a single treatment repeated after 15 days. Routine prophylaxis against dog ectoparasites was recommended by 82.4% veterinary practitioners, and 46.6% changed the drug compound used. Monthly prophylaxic treatments for ectoparasites, using systemic, topical and/or collar-impregnated drugs, was recommended by 21.5% veterinary practitioners. Side-effects of ectoparasiticide-impregnated collars were suspected by 58% of the veterinary practitioners. Isoxazolines were the most frequently used chemical group to treat ectoparasites in dogs. Poor efficacy of fipronil in controlling ticks was suspected by 79.5% of the veterinary practitioners. The isoxazolines and combination of anthelmintic compounds are the most common drugs to prevent or treat ectoparasites and gastrointestinal nematodes, respectively. The suspect of the inefficacy of antiparasitic drugs is shared among the veterinary practitioners from part of Brazil. Guidelines are needed, specifically for the control of gastrointestinal helminths and ectoparasites in Brazilian dogs.Reactive semivolatile contaminants, such as isocyanates, can be particularly difficult to assess in occupational environments. While standard methods exist for isocyanates, there are still significant differences between the results they provide for various occupational environments or processes. This study presents the validation of a laboratory system for the generation of controlled atmospheres of isocyanates. A system consisting of different modules generated airborne methylene diphenyl diisocyanate (MDI) by nebulizing a solution into mixing and exposure chambers with control of flow rate, temperature, and relative humidity. Sampling was performed through an eight-port flow splitter that allowed only very slight within-test variability. MDI was measured using the Asset EZ4-NCO® and a modified version of the Iso-Chek® sampling system. MDI specific particle-size distribution was measured by a Marple Sierra cascade. Aerosol real-time monitoring was performed using a condensation particle counter, an electrical low-pressure impactor (ELPI+), and an aerosol optical spectrometer, providing additional information on system stability and particle-size distribution of the generated aerosol. The system was able to generate MDI concentration levels ranging from 4 to 233 μg m-3, with a steady-state level reached within 5 minutes, and with well-documented intra-test and inter-test variability (RSD of 4% and 15%, respectively). Accuracy and representativeness of MDI data were confirmed by the agreement between MAMA and Asset EZ4-NCO (used as reference), with a mean bias of 3%. Using the Asset EZ4-NCO capability, the vapor-particle partitioning of MDI was evaluated to be 8% and 92%, respectively, at a concentration ranging from 20 to 25 μg m-3. The system may therefore be used for exhaustive method intercomparison studies and could also be adapted to generate other emission types of semivolatile compounds.Dissolved organic matter (DOM) in petroleum refinery wastewater is an extremely complex mixture. A better understanding of chemical compositions of DOM at the molecular level is necessary for the design and optimization of wastewater treatment processes. In this study, two largely different DOM samples, one from a petroleum refinery wastewater and the other from the Suwannee river water, were characterized by Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) coupled with positive-/negative-ion electrospray ionization (ESI), and positive-ion atmospheric pressure photoionization (APPI). For wastewater DOM, a total of 6226 molecular formulae were assigned in the three ionization modes. However, only 1182 molecular formulae were common in all three mass spectra, indicating that the techniques were highly complementary in the types of molecules they ionize. Acid Ox (x = 1-9) and basic N1Ox (x = 0-2) classes were dominant in the wastewater DOM detected in negative-ion and positive-ion ESI mode, respectively. And the wastewater DOM contains considerable amounts of polycyclic aromatic hydrocarbons that did not respond to ESI but can be ionized selectively by APPI. Compared with riverine DOM, the refinery wastewater DOM has a higher molecular complexity and is more enriched in hydrocarbon, and nitrogen- and sulfur-containing compounds. The results show that the major components of refinery wastewater DOM were distinctive from those of the natural organic matter. Though not quantitative, the results obtained by various ionization techniques were found to be complementary, and are helpful to our understanding of the selectivity of different ionization techniques as well as the molecular compositions of DOM.Wastewater treatment plants are suspected to be significant point sources of microplastic and nanoplastic particles (NPs) in the environment. read more As one of the main wastewater treatment processes, advanced oxidation processes (AOPs) may change the physicochemical properties of NPs and further affect their migration. However, limited information is known about the environmental fate of NPs after AOP treatment. In this study, polystyrene nanoparticles were treated using two representative AOPs, Fenton and persulfate treatments, and the migration of the NPs in quartz sand was investigated via column transport experiments. FTIR and XPS analysis indicated that a large number of oxygen-containing groups were generated on the NP surface after AOP treatment leading to lower hydrophobicity and a higher negative charge. Besides, the C/O ratio after Fenton and persulfate treatments was increased from 10.98 to 7.25 and 8.68. Moreover, the NPs after AOP treatment exhibited higher mobility in quartz sand in both ultrapure water and 10 mM NaCl solution. It was more obvious in 10 mM NaCl solution with breakthrough percentages of 79.73% for P-PS, 90.97% for F-PS and 95.67% for N-PS, respectively. These results could be explained by the roles of generated oxygen-containing functional groups; first, the higher negative charge enhanced the electrostatic repulsion between treated NPs and sand; second, lower hydrophobicity improved the binding with water molecules in background solution. This work is helpful in understanding the changes of nanoplastics in AOP treatment and their migration in the natural environment, which has far-reaching influence on the environmental fate and behavior of nanoplastics.
Website: https://www.selleckchem.com/products/azd7648.html
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