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ADHD Stimulant Medication
Stimulants can help people suffering from ADHD control their impulsive behavior and focus. They can be short- or long-acting and are prescribed by paediatricians, psychiatrists or neurologists (and doctors in certain situations).
Stimulants alter the levels of dopamine and norepinephrine levels in the brain. They are tightly controlled and are only prescribed by a physician.
Methylphenidate
Methylphenidate is part of the stimulant family and increases brain activity. It raises levels of certain chemicals, including noradrenaline and dopamine, which helps control the behavior and attention. Methylphenidate can be used to treat ADHD, narcolepsy and other disorders. It is also prescribed for depression in adults. However, it is not approved or regulated by the Food and Drug Administration. Methylphenidate is absorbed from the gut into the bloodstream quickly and works within hours. It is available as a tablet that releases immediately or an extended-release chewable capsule or tablet. The doctor will determine the most appropriate dosage based on the patient's symptoms and risk of side effects.
The side effects of methylphenidate tend to be minor and go disappear over time as the body gets used to the drug. Talk to your doctor in the event that they continue. He may reduce the dosage or suggest a different medication. It is essential to take the medication exactly as prescribed and not exceed the recommended dose. This lowers the chance of abuse or addiction. Methylphenidate is categorized as a Schedule II drug by the US Drug Enforcement Administration, which means it has a significant possibility of abuse. The stimulants can lead to dependence and withdrawal if they are not used as directed.
It is important to inform the doctor whether your child has heart issues, like irregular heartbeats or a history of heart attack. Methylphenidate can increase heart rate which is the reason why the doctor will check their blood pressure and heart rhythm before they start treatment. It is also essential to inform the doctor if your child is taking any other medications, like supplements, vitamins, or herbal supplements.
The doctor will inform you how much medicine to take and how often, as well any other precautions. Methylphenidate is recommended to be taken twice a day in conjunction with meals. Certain brands of long-acting methylphenidate chewable tablets (Quillichew ER, Cotempla XR-ODT and Adhansia XR) contain aspartame, which is a source of phenylalanine, and should not be taken by people with phenylketonuria (an inheritable condition that requires a low-protein diet to prevent severe intellectual impairment).
It is important to stay clear of the use of alcohol and other substances when taking this medication. Some people might notice their appetite diminishes when taking methylphenidate. If your child is losing weight, you should encourage them to eat a regular diet and snacks. You may need to remind them to drink plenty of water or squash in order to stay hydrated.
Lisdexamfetamine
Lisdexamfetamine, sold under the brand name Vyvanse is a central nervous system stimulant that affects the chemical activity of the brain and nerves. It improves concentration and impulse control in children, adolescents, and adults with ADHD. It treats eating disorders that cause binge eating (BED) as well as increasing levels of norepinephrine and dopamine in the brain. This helps to reduce uncontrolled eating.
Lisdexamfetamine is a member of the prodrug class that is a modified medication that is inactive until transformed in the body. It has demonstrated efficacy and safety in both stimulant-naive patients and stimulant exposed patients with ADHD. It is also believed to have a longer lasting effect than other stimulants and may have fewer rebound symptoms.
In a 12-week study that was placebo-controlled, Adler et al27 found significant improvements in ADHD-RS-IV scores. They also found that the majority of the patients who were switched to placebo relapsed after two weeks.28 In addition, Brams et al29 used an innovative design for an uncontrolled withdrawal study which they followed 116 adults for 12 weeks after stopping lisdexamfetamine treatment. They found that the majority of patients who relapsed were not exposed to any other stimulants in the two weeks preceding.
Tell your doctor if you have any allergies you may have to this medication, or any other medications. Inform your doctor if suffer from high blood pressure, heart problems or other heart-related conditions. Certain stimulants can increase the risk of having a stroke heart attack, stroke, or sudden death in people with these conditions.
Lisdexamfetamine may be absorbed into breast milk and could harm a nursing baby. It is advised not to breastfeed while taking this medicine. medication for adhd and anxiety may cause shakiness, dizziness, or stomach upset in some individuals. Lisdexamfetamine is not suitable for use by children less than six years old. Lisdexamfetamine cannot be used by women who are nursing or pregnant. You should not stop taking this medicine unless your doctor tells you to stop even when you are feeling better. Your doctor will probably be looking to check your blood pressure and heart rate when you take this medication.
Atomoxetine
Atomoxetine (Strattera) is a nonstimulant that works by blocking the presynaptic norepinephrine transporter. It has a high affinity to this transporter, but has a low affinity for other neurotransmitter receptors or transporters [115,136]. In multiple placebo-controlled research studies, it improved inhibitory control in ADHD patients by reducing overactivation of the right inferior frontal cortex (Chamberlain and colleagues. 2009). It was also shown to increase working memory and the ability to focus in children with ADHD. It takes up to 12 weeks to see its full effects. The dose is weight based and should be started low and gradually increasing. A daily dose of once is common. A poor metabolizer of the drug cytochrome P4502D6 (CYP2D6) has a greater exposure and a slower elimination of atomoxetine. The testing of the pharmacogenetics must be done before prescribing atomoxetine for these individuals.
It has been proven to be effective in reducing symptoms of ADHD in numerous controlled trials, and is often employed as the first-line treatment. It is generally well-tolerated and safe, and does not increase the risk of suicidal behavior. It is not as effective as stimulants in decreasing anxiety and tics and does not seem to decrease sleep issues, but it has been demonstrated to decrease aggression in some children. Atomoxetine is also more likely to interact with antidepressant fluoxetine. Therefore, it is not recommended to take them together [115, 137).
Clonidine (Catapres) and Guanfacine are two other medications that can be prescribed as treatments of first-line for ADHD. These drugs were initially developed to reduce high pressure in adults. These drugs are known as alpha agonists. They operate by stimulating receptors within the brain to release norepinephrine neurotransmitter which reduces the impulsivity and hyperactivity. These medications have a lengthy onset of action, and many children will require two to four weeks before seeing any benefits from them. They are also not recommended to be used with MAOIs, e.g. Phenelzine is not recommended due to the risk of serious and potentially fatal adverse reactions, including severe hypothermia and rigidity, myoclonus, and autonomic instability.
Other Stimulants
Stimulants are drugs which increase activity in the nervous system. They encompass a range of drugs, some legal and others illegal. They can be employed for a variety of reasons, such as performance enhancement, to stay alert and alert, and to treat certain medical conditions, such as ADHD, depression, and narcolepsy. Some examples of stimulants prescribed by a doctor are amphetamines and methylphenidate. The term"stimulant" could be used to describe non-prescription drugs like caffeine and certain diet pills, which are used for a variety reasons, but are not safe when used in combination with other medications or some foods.
Stimulants don't cause habit-forming doses prescribed for patients with ADHD, but they can have side effects. They can make people feel shaky or jittery. They can increase blood pressure and heart rate and cause stomach upset and cause trouble sleeping.
Some children and teens who are taking stimulants might experience the tics or repeated sounds or movements, such as eye blinking and throat clearing. They may also experience a minor growth delay.
A doctor will determine the most effective stimulant for you or your children. They will consider other factors, including age, weight and whether your child or you have any allergies. The doctor will then prescribe medications. Always follow your doctor's instructions. You should always go through the Medication Guide that is included with your prescription.
Medications are not the only method to treat symptoms of ADHD However, they're typically the first treatment option. Psychosocial interventions, such as family therapy and behavior modification are also available to help people of all ages with ADHD.
Patients who are taking prescription ADHD medication should be screened for the risk of abuse and misuse and advised not to share their medication with anyone else. Also it is recommended to store any medication they do not use in a safe place and dispose of them appropriately. Health care professionals must also regularly assess patients and monitor them for signs of misuse, abuse, or addiction. The FDA has demanded that more consistent information be provided on the labeling of drugs to help educate patients and families about the serious risks.
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