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Expressing the Same Standpoint. Emotional Problems and Key Serous Chorioretinopathy: A Systematic Report on Data through The year of 2010 for you to 2020.
logies that are designed for youth weight management and thus inform further research and clinical studies to reduce childhood obesity. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID) PRR1-10.2196/16930. ©Ching Lam, Madison Milne-Ives, Michelle Helena Van Velthoven, Edward Meinert. Originally published in JMIR Research Protocols (http//www.researchprotocols.org), 31.03.2020.BACKGROUND The United States is in the midst of an opioid epidemic. Long-term use of opioid medications is associated with an increased risk of dependence. The US Centers for Disease Control and Prevention makes specific recommendations regarding opioid prescribing, including that prescription quantities should not exceed the intended duration of treatment. OBJECTIVE The purpose of this study was to determine if opioid prescription quantities written at our institution exceed intended duration of treatment and whether enhancements to our electronic health record system improved any discrepancies. METHODS We examined the opioid prescriptions written at our institution for a 22-month period. We examined the duration of treatment documented in the prescription itself and calculated a duration based on the quantity of tablets and doses per day. We determined whether requiring documentation of the prescription duration affected these outcomes. RESULTS We reviewed 72,314 opioid prescriptions, of which 16.96% had a calculated duration that was greater than what was documented in the prescription. Making the duration a required field significantly reduced this discrepancy (17.95% vs 16.21%, P less then .001) but did not eliminate it. CONCLUSIONS Health information technology vendors should develop tools that, by default, accurately represent prescription durations and/or modify doses and quantities dispensed based on provider-entered durations. This would potentially reduce unintended prolonged opioid use and reduce the potential for long-term dependence. ©Benjamin H Slovis, John Kairys, Bracken Babula, Melanie Girondo, Cara Martino, Lindsey M Roke, Jeffrey Riggio. Originally published in JMIR Medical Informatics (http//medinform.jmir.org), 31.03.2020.BACKGROUND Recent research has investigated the utility of mobile phone-delivered interventions for reducing risky single-occasion drinking, also known as binge drinking. In the past five years, focus has been placed on ecological momentary interventions (EMIs), which aim to deliver intervention content in correspondence to real-time assessments of behavior, also known as ecological momentary assessments (EMAs). OBJECTIVE This study aims to assess the effect of a fully automated, tailored, mobile phone-delivered EMI termed Mobile Intervention for Drinking in Young people (MIDY) on young people's risky single-occasion drinking behavior. METHODS We will use a three-armed randomized controlled trial design to determine the impact of MIDY on peak consumption of alcohol among young people. A list of mobile telephone numbers for random digit dialing will be generated, and researchers will telephone potential participants to screen for eligibility. Participants will be randomized into one of three intervention groupTR) ACTRN12617001509358p; http//www.anzctr.org.au/ACTRN12617001509358p.aspx. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID) DERR1-10.2196/14190. ©Cassandra Jane Carlin Wright, Paul M Dietze, Emmanuel Kuntsche, Michael Livingston, Paul A Agius, Robin Room, Michelle Raggatt, Margaret Hellard, Megan S C Lim. Originally published in JMIR Research Protocols (http//www.researchprotocols.org), 31.03.2020.BACKGROUND Liver cirrhosis results from chronic hepatitis, and is characterized by advanced fibrosis due to long-term hepatic inflammation. Cirrhosis ultimately leads to manifestations of jaundice, ascites, and encephalopathy, and increases the risk of hepatocellular carcinoma. Once cirrhosis is established, resulting in hepatic failure, no effective treatment is available. Therefore, novel therapies to inhibit disease progression of cirrhosis are needed. OBJECTIVE The objective of this investigator-initiated clinical trial is to assess the safety and efficacy of autologous adipose tissue-derived regenerative (stem) cell therapy delivered to the liver via the hepatic artery in patients with liver cirrhosis. METHODS Through consultation with the Japan Pharmaceuticals and Medical Devices Agency, we designed a clinical trial to assess a therapy for liver cirrhosis based on autologous adipose tissue-derived regenerative (stem) cells, which are extracted using an adipose tissue dissociation device. The primary end Yasuhito Imai, Kenichi Yoshimura, Toshinori Murayama, Takashi Wada, Kenichi Harada, Kazuhide Higuchi, Shuichi Kaneko. buy Sovleplenib Originally published in JMIR Research Protocols (http//www.researchprotocols.org), 31.03.2020.BACKGROUND Individuals in stressful work environments often experience mental health issues, such as depression. Reducing depression rates is difficult because of persistently stressful work environments and inadequate time or resources to access traditional mental health care services. Mobile health (mHealth) interventions provide an opportunity to deliver real-time interventions in the real world. In addition, the delivery times of interventions can be based on real-time data collected with a mobile device. To date, data and analyses informing the timing of delivery of mHealth interventions are generally lacking. OBJECTIVE This study aimed to investigate when to provide mHealth interventions to individuals in stressful work environments to improve their behavior and mental health. The mHealth interventions targeted 3 categories of behavior mood, activity, and sleep. The interventions aimed to improve 3 different outcomes weekly mood (assessed through a daily survey), weekly step count, and weekly sleep timeEGISTRATION ClinicalTrials.gov NCT03972293; http//clinicaltrials.gov/ct2/show/NCT03972293. ©Timothy NeCamp, Srijan Sen, Elena Frank, Maureen A Walton, Edward L Ionides, Yu Fang, Ambuj Tewari, Zhenke Wu. Originally published in the Journal of Medical Internet Research (http//www.jmir.org), 31.03.2020.
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