Notes

Existing condition of transcatheter mitral valve implantation within bioprosthetic mitral device as well as in mitral ring as a remedy approach for failed mitral prosthesis.
3±1.4. The mean number of medications used at 12, 18 and 24 months was respectively 2.6±1.5, 2.5±1.4 and 2.2±1.5. Postoperative complications included cystic macular edema (n=2), hypotony maculopathy (n=1), fibrinous/uveitic reaction (n=1) and rejection of corneal graft (n=1), all reversible after treatment. One patient developed persisting hypotony in the late postoperative period. Conclusion Micropulse TSCPC is a safe and effective treatment for lowering both IOP and the number of IOP-lowering medications. Micropulse TSCPC can also be considered as a good alternative treatment option for patients after failed incisional glaucoma surgery or patients who are at high risk for incisional surgery.Glaucoma is typically defined as a progressive optic neuropathy characterized by a specific (arcuate) pattern of visual field (VF) and anatomical changes. Therefore, we should be comparing arcuate patterns of damage seen on VFs with those seen on optical coherence tomography (OCT) maps. Instead, clinicians often use summary metrics such as VF pattern standard deviation (PSD), OCT retinal nerve fiber (RNF) global thickness, etc. There are two major impediments to topographically comparing patterns of damage on VF and OCT maps. First, until recently, it was not easy to make these comparisons with commercial reports. While recent reports do make it easier to compare VF and OCT maps, they have shortcomings. In particular, the 24-2 VF covers a larger retinal region than the commercial OCT scans, and, further, it is not easy to understand the topographical relationship among the different maps/plots within the current OCT reports. Here we show how a model of RNF bundles can overcome these problems. The second major impediment is the lack of a quantitative, and automated, method for comparing patterns of damage seen on VF and OCT maps. However, it is now possible to objectively and automatically quantify this agreement. Together, the RNF bundle model and the automated structure-function method should improve the power of topographical methods for detecting glaucoma and its progression. This should prove useful in clinical studies and trials, as well as for training and validating artificial intelligence/deep learning approaches for these purposes.PRéCIS The present study demonstrates that the surgical success rate of circumferential trabeculotomy is 64.7% according to target IOP ≤21▒mmHg and 30% ≥reduction from baseline in patients with neonatal-onset primary congenital glaucoma, with an average follow-up of 35.1 months. Purpose The aim of the study was to evaluate the surgical success rate and applicability of circumferential trabeculotomy compared with converted traditional trabeculotomy in patients with neonatal-onset primary congenital glaucoma (PCG) in Turkey. Patients and methods A retrospective study enrolled 42 eyes of 42 patients with an average age of 34.0±6.7 (14-59) days at the time of the surgery, who underwent 5/0 prolene suture-assisted circumferential trabeculotomy or rigid probe-assisted traditional trabeculotomy for the treatment of neonatal-onset PCG. SCH58261 purchase Intraocular pressure (IOP) at baseline, first, second, third, sixth, 9, 12, 24 and 36 months of follow-up, need of glaucoma eye drop, need of further glaucoma surgery, cup/disc ratio, effect of circumferential trabeculotomy could be maintained up to ~36 months.Purpose To compare the visual field (VF) parameters of the new Swedish Interactive Thresholding Algorithm, SITA Faster (SFR) with that of SITA Standard (SS) on the Humphrey Field Analyzer. Methods Ninety-seven eyes of 97 subjects (63 glaucoma, 26 glaucoma suspects and 8 normal eyes) underwent VF examination with SFR and SS strategies on the same day in random order. Agreement in VF parameters between SFR and SS strategies was assessed by Bland and Altman plots. Additionally, some subjects underwent a second VF examination with SFR strategy to evaluate its test-retest variability. Results The median test duration of SS strategy was 6 minutes 14 seconds while SFR was 2 minutes 49 seconds (55% shorter, P less then 0.001). Median MD (-7.3 vs. -7.6▒dB, P=0.73) and VFI (88 vs. 88%, P=0.32) were similar between the 2 strategies, while PSD was significantly higher (4.8 vs. 4.7▒dB, P=0.01) with SS strategy. Overall average threshold sensitivity and Garway-Heath sector-wise threshold sensitivities were similar between the two strategies except the nasal sector where SFR strategy had higher sensitivity (26 vs. 25▒dB, P=0.02). Bland-Altman plots showed the mean difference in all VF parameters between the SS and SFR strategies were small (ranging from -1.0▒dB for nasal sector to -0.01▒dB for supero-temporal sector sensitivity). The test-retest variability of VF parameters with SFR strategy was low. Conclusions VF parameters with SFR showed good agreement with that of SS strategy. This, combined with low test-retest variability, suggests that SFR can be considered for diagnosis and monitoring of glaucoma.Purpose To evaluate the efficacy of intraocular pressure (IOP) control after combined CyPass Micro-Stent implantation and cataract surgery (combined surgery). Methods All cases of combined surgery performed from 2/2017 to 7/2018 at Stein and Doheny Eye Institutes were reviewed. Primary outcome was qualified success with stratified IOP targets based on criteria Final IOP (A) ≤18▒mmHg and reduction of 20%, (B) ≤15▒mmHg and reduction of 25%, (C) ≤12▒mmHg and reduction of 30%. Secondary outcome measures included postoperative IOP and number of medications, complications, additional glaucoma surgery, and postoperative refractive error. Predictive factors for failure were investigated. IOP spike was defined as postoperative IOP ≥30▒mmHg or >10▒mmHg increase from preoperative IOP. Results One hundred and forty-one eyes (107 patients) were included. Mean (±SD) preoperative IOP was 15.4±3.4▒mmHg on an average of 2.2±1.1 medications. A statistically significant reduction in IOP and number of medications was seen at 12 months (13.8±4.2▒mmHg, 1.3±1.3 medications, P less then 0.001). Fifteen eyes (10.6%) had a postoperative IOP spike. Thirteen eyes (9.2%) experienced 17 complications (12.1%). Additional glaucoma surgery was performed in 3 eyes (2 patients). Cumulative success rates at one year based on criteria A, B, and C were 42%, 33%, and 28%, respectively. Lower preoperative IOP, greater preoperative medication number, occurrence of postoperative IOP spike, and non-Caucasian ethnicity were associated with failure. Conclusion Combined CyPass Micro-Stent implantation and cataract surgery may reduce glaucoma medication burden with a success rate of 28% to 42% at one year.
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