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001), log estimated glomerular filtration rate (eGFR) (
< 0.001), overt nephropathy (defined as AER ≥ 200 µg/min,
= 0.06), and multiple daily insulin shots/pump use (MDI) exposure years (
= 0.02) were independent predictors of SIF score change.
Increases in SIF score over 5 years were related to increased glycemic levels and decreased kidney function (eGFR). MDI and glomerular damage were related to a decreased SIF score. This is one of the first studies with repeated SIF assessments in T1D and provides unique, albeit preliminary, insight about these associations.
Increases in SIF score over 5 years were related to increased glycemic levels and decreased kidney function (eGFR). MDI and glomerular damage were related to a decreased SIF score. This is one of the first studies with repeated SIF assessments in T1D and provides unique, albeit preliminary, insight about these associations.Phylogenetic analyses increasingly take centre-stage in our understanding of the processes shaping patterns of cultural diversity and cultural evolution over time. Just as biologists explain the origins and maintenance of trait differences among organisms using phylogenetic methods, so anthropologists studying cultural macroevolutionary processes use phylogenetic methods to uncover the history of human populations and the dynamics of culturally transmitted traits. In this paper, we revisit concerns with the validity of these methods. Specifically, we use simulations to reveal how properties of the sample (size, missing data), properties of the tree (shape) and properties of the traits (rate of change, number of variants, transmission mode) might influence the inferences that can be drawn about trait distributions across a given phylogeny and the power to discern alternative histories. Our approach shows that in two example datasets specific combinations of properties of the sample, of the tree and of the trait can lead to potentially high rates of Type I and Type II errors. We offer this simulation tool to help assess the potential impact of this list of persistent perils in future cultural macroevolutionary work. This article is part of the theme issue 'Foundations of cultural evolution'.A specific goal of the field of cultural evolution is to understand how processes of transmission and selection at the individual level lead to population-wide patterns of cultural diversity and change. Models of cultural evolution have typically assumed that traits are independent of one another and essentially exchangeable. But culture has a structure traits bear relationships to one another that affect the transmission and selection process itself. Here, we introduce a modelling framework to explore the effect of interdependencies on the process of learning. Through simulations, we find that introducing a simple structure changes the cultural dynamics. Based on a basic filtering mechanism for parsing trait relationships, more elaborate cultural filters emerge. In a mostly incompatible cultural domain of traits, these filters organize culture into mostly (but not fully) consistent and stable systems. Incompatible domains produce small homogeneous cultures, while more compatibility increases size, diversity and group divergence. When individuals copy based on a trait's features (here, its compatibility relationships), they produce more homogeneous cultures than when they copy based on the agent carrying the cultural trait. Linderalactone clinical trial We discuss the implications of considering cultural systems and filters in the dynamics of cultural change. This article is part of the theme issue 'Foundations of cultural evolution'.Modern phylogenetic methods are increasingly being used to address questions about macro-level patterns in cultural evolution. These methods can illuminate the unobservable histories of cultural traits and identify the evolutionary drivers of trait change over time, but their application is not without pitfalls. Here, we outline the current scope of research in cultural tree thinking, highlighting a toolkit of best practices to navigate and avoid the pitfalls and 'abuses' associated with their application. We emphasize two principles that support the appropriate application of phylogenetic methodologies in cross-cultural research researchers should (1) draw on multiple lines of evidence when deciding if and which types of phylogenetic methods and models are suitable for their cross-cultural data, and (2) carefully consider how different cultural traits might have different evolutionary histories across space and time. When used appropriately phylogenetic methods can provide powerful insights into the processes of evolutionary change that have shaped the broad patterns of human history. This article is part of the theme issue 'Foundations of cultural evolution'.This article outlines how the historical human sciences see 'culture' and its dynamic developments over time and over generations. The operations of human culture are systemically self-reflexive and, as a result, exhibit a complexity that sets them apart, as a semiotic system, from mere communicative information transfer. Peculiar to this complexity is the two-way interaction between the 'etic' substance of the cultural exchanges and their 'emic' function. Cultural signals require parallel etic/emic processing at stacked levels of complexity. As a result of this complexity, the homeostasis and autopoiesis of human culture, including its dynamics and development over time, cannot be explained fully in terms of responses to the physical environment. How, this article ponders by way of conclusion, can an evolutionary approach be reconciled with these characteristics of human culture, or the notion of culture be applied to evolutionary modelling? This article is part of the theme issue 'Foundations of cultural evolution'.Theories of cultural evolution rest on the assumption that cultural inheritance is distinct from biological inheritance. Cultural and biological inheritance are two separate so-called channels of inheritance, two sub-systems of the sum total of developmental resources travelling in distinct ways between individual agents. This paper asks what justifies this assumption? In reply, a philosophical account is offered that points at three related but distinct criteria that (taken together) make the distinction between cultural and biological inheritance not only precise but also justify it as real, i.e. as ontologically adequate. These three criteria are (i) the autonomy of cultural change, (ii) the near-decomposability of culture and (iii) differences in temporal order between cultural and biological inheritance. This article is part of the theme issue 'Foundations of cultural evolution'.
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