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Mesothelioma and Asbestos Exposure
People who use asbestos-containing products are at risk of ingesting asbestos fibers. The fibers penetrate the wall of the chest cavity and abdomen, known as the pleura or the peritoneum.
The exposure to asbestos increases the lifetime risk of malignant pleural or peritoneal mesothelioma. Although the risk is believed to diminish after 40 years, exposure to asbestos of any kind is dangerous.
Age
The older a person gets when exposed, the greater the chance of developing mesothelioma. Mesothelioma can be described as a cancer that affects mesothelium, which is a thin layer of tissue surrounding the major organs of the body. The cancerous cells are malignant, meaning they expand beyond control and develop into tumors. Mesothelioma is most often seen in those who have been exposed to asbestos. This could be due to their work or as a close family member.
Exposure to asbestos can cause mesothelioma due to irritation of the mesothelium. The lung's lining (pleura) is most affected in patients suffering from pleural mesothelioma, although it can also affect the lining of the abdomen and peritoneum as well as the heart lining (pericardium).
Asbestos is a non-porous and durable mineral. It was used in construction, insulation and other industrial applications prior to the 1980s. In this time many millions of Americans were exposed to asbestos as a result of their jobs or by being close to an exposed loved one.
When asbestos is disturbed, it releases fibers into air. They are too hard for the body's system to break into pieces or process. The fibers could be trapped in the lungs and cause irritation that can lead to cancer.
Mesothelioma symptoms are typically not likely to show up until years after asbestos exposure. The symptoms are similar to those of other types of cancer and can be fatal if left untreated.
Men are more likely to be affected by mesothelioma than women. It is also diagnosed most often for those who are older than 45. Miners, shipbuilders, railroad workers, and those who installed or handled asbestos-containing items are at the most chance of developing mesothelioma due to asbestos exposure in the workplace. Irvine asbestos attorney in the clothing of these people can also expose their families to risk.
Smoking
The longer someone is exposed to asbestos, the greater the risk of developing mesothelioma. This is due to the lengthy latency time that can range between 20 and 60 year from first exposure until diagnosis. Mesothelioma can be found in various areas of the body based on the type and quantity of asbestos present. Pleural mesothelioma can be found in the lining between the lung cavity and the chest wall (the pleura). Peritoneal mesothelioma develops in the abdominal lining, called the peritoneum.
Anyone who has been exposed to asbestos the most often develop mesothelioma that is found in their chests or the lungs. The most at risk are those who worked in shipbuilding, power production and construction. Mesothelioma is also a possibility for those who were exposed at home or at school to asbestos. This is due to the fact that children and spouses of workers who were exposed to asbestos may carry the asbestos fibers into their clothes hair, skin, and skin which puts them at risk of developing the disease.
Mesothelioma patients are usually white and older than 65. They are more likely to have an occupation that was blue collar or a military background. The United States Navy and other branches of the military have used asbestos extensively due to its flame-resistant properties, and millions of veterans could have been exposed to asbestos.
Mesothelioma can form when an individual's DNA undergoes changes which cause cells to multiply without control. This leads to the formation of tumors that eventually develop into mesothelioma. The disease can affect the entire body, but it is most common in the abdomen and chest.
Smoking does cause mesothelioma but it increases your risk by increasing the amount of asbestos you breathe in. Anyone who has been exposed to asbestos should quit smoking cigarettes.
In addition, a mesothelioma treatment program should include a doctor who understands asbestos exposure and the risk factors for this type of cancer. A specialist in mesothelioma who is knowledgeable with them can help them determine the best method to treat this rare cancer. The doctor will be able to determine whether a patient is eligible for immunotherapy or other experimental treatments.
Asbestos Exposure
Asbestos is a natural mineral that is utilized in many different products including flooring, roofing, and insulation. Workers who handle, manufacture or work with asbestos-containing materials are at high risk for exposure. Exposure to loose asbestos fibers can result in breathing them into the lungs where they can cause illness or cancer.
Many asbestos-related illnesses are not recognized until it is too late because there is a long latency period between exposure and the development of symptoms. Mesothelioma, the most dangerous of asbestos-related illnesses, is no exception. Mesothelioma symptoms can manifest between 20 and 60 years after exposure to asbestos.
Exposure to occupational hazards is the most frequent way in which people are exposed. Construction, manufacturing, electrical and automotive mechanic jobs all involve handling or using asbestos components and materials. Some people are also exposed by their home activities such as smoking or renovating older homes that have asbestos.
Inhalation of asbestos is the most common mesothelioma-related cause. Asbestos particles that are inhaled can travel into the lungs and irritate the lining known as the pleura. This irritation causes the formation of thickened pleura patches (pleural plaques) and fibrosis of the lungs. As the disease progresses, it can result in the accumulation of fluid in the chest cavity (pleural effusion) and ultimately to lung cancer. Mesothelioma can also affect the tissues of other organs, including the abdomen and heart.
Mesothelioma is most common in those who have been exposed to asbestos working. However, people with the family history of mesothelioma or other asbestos-related illnesses are also at risk. The risk of exposure to asbestos is increased if a person has had more than one job in the course of their life. Smoking cigarettes can increase the risk of mesothelioma, but it can worsen the condition for those already diagnosed. If you have a history of exposure to asbestos and experience mesothelioma, quitting smoking can make you healthier and improve your treatment outcome. Tell your doctor if you have been exposed to asbestos or if you notice any new symptoms like abdominal pain or shortness of breathing. They may prescribe medication or undergo surgery to treat the condition.
Genetics
Many cancers have a genetic connection which means that genetic factors increase the likelihood of getting a specific disease. However, mesothelioma does not have an element of genetics. Instead exposure to asbestos is the main reason.
Asbestos fibers are introduced into the body through inhalation or swallowed, and they stick to the chest's lining (the pleura) and the abdomen (the peritoneum) or around the heart (the pericardium). As time passes the loose fibers could alter or damage the cells that comprise these small linings, which could lead to mesothelioma development.
But, not every person exposed to asbestos gets mesothelioma. Researchers believe that other factors could influence whether someone develops mesothelioma from asbestos exposure. This includes a person's age and gender as well as their family history of mesothelioma and other diseases and whether they have additional risk factors, such as smoking.
Men are more likely than women to develop mesothelioma. This could be due to the fact that more men than women were exposed directly to asbestos at work. It can take between 20 and 60 years for mesothelioma to be diagnosed following a person's initial exposure to asbestos.
A faulty gene is another risk factor for mesothelioma. In a study looking at two families with high rates of mesothelioma, researchers discovered that nearly every member of the family had a faulty gene on their short arm of chromosome 3. This gene, called BAP 1, regulates the movement of calcium inside cells. A defect in the gene causes disruption to this process which causes calcium levels to drop. This causes asbestos to transform healthy cells into cancerous ones, causing mesothelioma.
Additionally, a mutated gene in the immune system of a person could also raise the chance of developing mesothelioma after exposure to asbestos. The mutation results in an increase in white blood cells. These cells are responsible for fighting cancerous cells.
Other factors that can raise the chance of developing mesothelioma include the kind of asbestos they were exposed to as well as their work. Additionally, the polio vaccine given to children in the 1940s and 1950s could increase a person's mesothelioma risk because it exposed them to the cancer-causing SV40 virus.
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