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Evaluation of in-situ gel-forming vision fall made up of bacteriophage versus Pseudomonas aeruginosa keratoconjunctivitis inside vivo.
BACKGROUND Patients with complex chronic conditions experience fragmentation of care, unnecessary hospitalisation and reduced quality of life, with an increased incidence of poor health outcomes. AIM(S) The aim of this paper is to explore how nurse navigators manage client care. This was achieved through an examination of narratives provided by the nurse navigator that evaluated their scope of practice. METHOD(S) All nurse navigators employed by Queensland Health were invited to participate in a study evaluating the effectiveness of the service. Eighty-four self -reported vignettes were thematically analysed to understand the work from the nurses' perspectives. RESULTS Two themes emerged from the vignettes. Theme one, the layers of complexity, is comprised of three sub-themes the complex patient, the complex system, and patient outcomes. Theme two, professional attributes, has two sub-themes person-centred care and clinical excellence. CONCLUSION Navigators innovatively integrate services and address the fragmented nature of the health system. They apply expert clinical and social skills, through consistent and robust communication, to meet the needs of those with multiple chronic conditions. IMPLICATIONS FOR NURSING MANAGEMENT Results provide insight into the new role, illuminating the work they achieve, despite system complexities. This article is protected by copyright. All rights reserved.AIMS AND OBJECTIVES The study aim was to develop and evaluate a nurse-led sexual health service and health promotion intervention for men in prison. BACKGROUND Men in prison are particularly marginalised members of our society, negatively impacting on their ability to making healthy choices. In relation to sexual health, prison provides an opportunity for curative and preventive care, for an otherwise often hard to reach priority population. DESIGN Practice development, audit and evaluation. METHODS Employing a practice development and participatory methodology, we empowered prison nursing staff to provide robust asymptomatic testing for sexually transmitted infections, including the management of chlamydia, with appropriate treatment and partner notification. Collaboratively with young men and nursing staff, a short animation video to promote the service was developed. A case note audit of 172 patients seen in the service during the 6 month period 1st July 2018 - 31 December 2018 was undertaken. The Standards for Quality Improvement Reporting Excellence (SQUIRE) checklist was followed. RESULTS National outcomes measures were exceeded for some clinical outcomes. During the 6 month period, there were 12 positive chlamydia (7% positivity rate) and 3 gonorrhoea positive results. In addition, 2 new cases of syphilis were detected and a further 2 cases of known HIV were highlighted. There were 7 cases of Hepatitis C (3 previously diagnosed) and 3 cases of Hepatitis B. A short animation Dick Loves Doot was developed. CONCLUSION Successful partnerships between sexual health and prison healthcare services, in partnership with service users, can achieve well-co-ordinated services and health promotion interventions. RELEVANCE TO CLINICAL PRACTICE This nurse led model of care increased detection and early treatment of asymptomatic STIs among men in prison, impacting positively the men, their partner (s) and the public health of the society to which they return. This article is protected by copyright. All rights reserved.BACKGROUND Leaving infant to cry it out has been the subject of discussion among researchers and parents. Nevertheless, there is paucity of empirical research investigating the association between leaving infant to cry it out and consequent crying duration and frequency, mother-infant attachment and behavioural development. METHODS The sample with complete longitudinal data comprised 178 infants and their caretakers. Parental use of 'leaving infant to cry out' and cry duration were assessed with maternal report at term, 3, 6 and 18 months, and frequency of crying was assessed at term, 3 and 18 months of age. Attachment was measured at 18 months using the strange situation procedure. Behavioural development of the infant was assessed with two observational measures and a parent-report questionnaire at 18 months. RESULTS The use of 'leaving infant to crying' was rare at term and increased over the next 18 months. 'Leaving infants to cry it out' at term was associated with a decrease in crying frequency at 3 months. Furthermore, leaving infants to cry it out a few times at term and often at 3 months was associated with shorter fuss/cry duration at 18 months of age. No adverse impacts of leaving infants to cry it out in the first 6 months on infant-mother attachment and behavioural development at 18 months were found. CONCLUSIONS Contemporary practice of some parents in the United Kingdom to occasionally or often 'leaving infant to cry it out' during the first 6 months was not associated with adverse behavioural development and attachment at 18 months. Increased use of 'leaving to cry it out' with age may indicate differential responding by parents related to infant self-regulation. © 2020 Association for Child and Adolescent Mental Health.An enantiomerically pure (R)-2-methylpyrrolidine-based anilino squaraine crystallizes in two chiral polymorphs adopting a monoclinic C2 and an orthorhombic P21 21 21 structure, respectively. By various thin-film preparation techniques, a control of the polymorph formation is targeted. The local texture of the resulting textured thin films is connected to the corresponding optical properties. Special attention is paid to an unusual Davydov splitting, the anisotropic chiroptical response arising from preferred out-of-plane orientation of the crystallites, and the impact of the polymorph specific excitonic coupling. © 2020 The Authors. Chirality published by Wiley Periodicals, Inc.The aim of current study was to assess the antioxidant and renoprotective effects of Stachys pilifera Benth (S.P.B.) hydroalcoholic extract on nephrotoxicity induced with cisplatin (CP). Adult rats with bodyweight of 180-220 g were divided into five groups (n = 7) treated as follows group 1, control; group 2, CP; group 3, pretreatment with S.P.B. before CP; group 4, posttreatment with S.P.B. after CP; and, group 5, S.P.B. extract. GO-203 solubility dmso A single dose of CP (7 mg/kg) was intraperitoneally injected on the fifth day and hydroalcoholic extract of S.P.B. (500 mg kg-1 day-1 ) was orally administered. The levels of oxidative stress markers, biochemical tests, and histopathological staining were assayed in serum and renal tissue. Also, the chemical composition of S.P.B. extract was determined by GC-MS analysis. The main compositions of S.P.B. extract identified by GC-MS analysis, were hexadeca-2,6,10,14-tetraen-1-ol, 3,7,11,16-tetramethyl (24.77%), thymol (14.1%), and linolenic acid (13.4%). In groups treated and pretreated with S.
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