Notes

Implications of recent studies pertaining to latest mental kinds of common folks recognition.
5 and 1.8 times on the 7th day, indicating the cytolytic syndrome with cholestasis. The adrenaline administration to experimental rats for 3 weeks was accompanied by an increase of chondroitin-6 and chondroitin-4-sulfates in the serum content and a decrease in heparan sulfates, which indicated the development of liver fibrosis.The present study was aimed to determine the parents' knowledge level about vit D importance for children normal health state, functions of vit D, sources, recommended duration of supplementation or treatment.The questionnaire was utilized as cross-sectional survey to determine the awareness of parents about vit D influence and importance for child health. The questionnaire was designed by the author. The survey questions covered the topics of parents'/caregivers' information needs; understanding of importance of vit D supplementation, causes of vit D deficiency, duration of supplementation, importance of screening adolescent girls for vit D deficiency. The survey was administered to parents/ caregivers of children of age from 1 to 15 years old living in Tbilisi and different regions of Georgia. The data were analyzed using Excel.A total 850 individuals participated in the study. Most of them 88,3% believed vit D to be important for health of a child, but could not explain why. 74% of respondents could identify oily fish or eggs as main source of vit D. However, 46% believed dairy products to be a good dietary source of vitamin D. More than 59% of participants supported their children by vit D drops up to age of 1 year, 40% by themselves decide to give it only 1-2-months. Only 12% of mothers continue to support her child by vit D till 24 months and more. About the importance for vit D deficiency prevention among adolescent girls, as for future mothers, 85,3 % of participants answered they have no information about this. According to received results, the parental awareness and level of knowledge about vit D importance for child normal growth and health is poor.Sothere is a need for increased levels of parental education to ensure children have a better chance of maintaining adequate vitamin D levels.The article describes one of the forms of 46 XY DSD which is related to androgen peripheral actions. There are two disorders related to DSD with preserved testosterone production by the testes, which are Androgen insensitivity syndrome (AIS) and type 5α-reductase deficiency. Although the above-mentioned conditions have similar clinical manifestations, they are initiated by different pathogenetic mechanisms. AIS has X-linked recessive inheritance pattern and is presented by total or partial insensitivity of androgen receptors to male sex hormones.The new Coronavirus has challenged modern medicine. The disease caused by this virus, COVID-19, is characterized by a high rate of lethality, especially in the older age group. There is still no vaccine and no specific treatment, therefore prevention remains the main way to fight the virus. SARS-COV-2 is characterized by high virulence and contagiousness, that's why the main preventive recommendation is social distance. The article reviews the features of this virus, ways of invading the virus in the body, the possible pathogenesis of the disease and the biochemical and pharmacological aspects of symptomatic treatment. The article also discusses the views of various authors, the results of previous studies and sets new perspectives on fighting the virus. The article discusses the mechanism of action of all drugs and the possible impact on the course and outcome of the disease, which has led to differences of opinion among various groups of scientists since the spread of the virus.The aim of the work is to investigate the influence of serological markers of blood groups on the development of the time perception function in adolescent athletes taking into account sexual dimorphism. The study involved girls (n=178) and boys (n=139) from a specialized sports institution, who according to the classification of sports by A.G. Dembo were divided into two groups group A - speed and power sports, group B - endurance sports. The control group consisted of pupils [girls (n=117), boys (n=106)] aged 13-15 years and students [girls (n=115), boys (n=150)] aged 17-20 years, who did not play sports. The research of the time perception function was carried out according to the method of V.L. Maryshuk et al., the prototype of which is the method of D.Zakay, R.A. Block. The fact of possible use of blood groups in genetic prediction of development of time perception was established. Individuals of male and female sex with blood group B (III) have been found to have the best associative relation with the properties of this function, while the worst relation remains unclear. The properties of time perception are more expressively manifested in students in late adolescence than in pupils in early adolescence. NVP-TNKS656 It was found that sexual dimorphism does not make significant adjustments in the specifics of changes in the time perception function, but genetic markers of blood groups are more informative in predicting the development of the above-mentioned mental quality in boys with B (III) blood group than in girls with the same blood group.Aim of our study is to establish polysomnographic characteristics of nocturnal sleep in various forms of multiple sclerosis. Fifty eight patients with different clinical course of multiple sclerosis (MS) were included into the study. Disturbances of sleep architectonics were identified representation of deep stages of NREM sleep, as well as REM sleep were reduced. Maintenance and continuity of sleep and its architecture were affected, leading to reduced sleep efficacy. Destabilization of sleep phases can be explained by activation of desynchronizing brain systems, leading to poor organization of NREM and REM sleep. These disorders were especially pronounced in patients with progressive course of MS. Thus, abovementioned sleep disorders can have prognostic value for predicting clinical course severity in patients with MS. Management of sleep disorders can improve quality of live in people with MS.
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