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there are many factors perceived to contribute towards high HIV prevalence among adolescents. Our study suggests urgent need for the country to sustainably address key harmful cultural and social practices that potentially increase adolescents´ vulnerability to HIV.
there are many factors perceived to contribute towards high HIV prevalence among adolescents. Our study suggests urgent need for the country to sustainably address key harmful cultural and social practices that potentially increase adolescents´ vulnerability to HIV.
markers in breast cancer stem cells, such as cluster of differentiation 10 (CD10), would be correlated with invasive and metastatic potential of several types of cancer, contributing to tumor growth and metastases. In patients with breast cancer, its prognostic value is still controversial, given the discrepancy of results. The purpose of the study was to study CD10 expression in stromal cells of patients with breast cancer as well as to evaluate the prognostic value of this expression.
we conducted a retrospective, descriptive and prognostic study. It involved 57 patients with invasive cancer of no special type, whose data were collected in the Department of Pathological Anatomy at the Mongi Slim Hospital over a 38-month period. CD10 expression was studied immunohistochemically and interpreted by semi-quantitative scoring system based on three categories with thresholds of 10 and 30%.
the average age of patients was 56.4 years. Twenty-eight patients (49%) had labeled CD10 stromal, half of patients had a score of 1 (low) and the other half had 2 (high). This labeling significantly reduced recurrence-free survival (p=0.001). However, it had no influence on overall survival (p=0.84). The correlation study showed that CD10 expression in stromal cells was significantly correlated with 12 poor prognostic factors in patients with breast cancer.
CD10 expression in stromal cells of invasive breast cancer is a poor prognostic factor, predictive of poor survival without recurrence and associated with a high invasive and metastatic potential.
CD10 expression in stromal cells of invasive breast cancer is a poor prognostic factor, predictive of poor survival without recurrence and associated with a high invasive and metastatic potential.Congenital vaginal atresia is a rare congenital abnormality of the female reproductive tract due to a failure of canalisation in the urogenital sinus. We report the uncommon case of a 14-year-old girl with a primary amenorrhea associated to a cyclical pelvic pain, in whom examination objectified a vaginal cup that replaced the introitus. Ultrasound examination and magnetic resonance imaging (MRI) revealed atresia of the lower third of the vagina. The diagnosis of partial vaginal aplasia on functional uterus was retained, the patient had a perineal vaginoplasty. The evolution was satisfactory with regular cycles and improvement of pelvic pain. The decline is three years. Congenital vaginal atresia is a rare malformation classically and clinically pictured as a primary amenorrhea with chronic cyclic pelvic pain. Diagnosis is based on clinical examination and imaging. The MRI is designed to assess the importance of atresia and guide surgical management while the surgical technique aims to restore the integrity of the utero-vaginal tract and to increase the possibility of pregnancy for these patients.
sexually transmitted infections (STIs) are infections that are transmitted from one person to another through sexual contact, and most of them are easily preventable and treatable. Global trends in STIs have increased. Sub-Saharan Africa carries a high burden of STIs, including HIV. Knowledge about STIs is very significant for preventing the adverse outcomes of young adult reproductive health. Therefore, this study aimed to assess the knowledge of sexually transmitted diseases and its associated factors among polytechnic college students in Southwest Ethiopia.
a cross-sectional study was conducted among 453 randomly selected students at Mizan-Aman polytechnic college in Southwest Ethiopia from April 1
to 30
, 2018. The data were collected through self-administered structured and pre-tested questionnaire. The collected data were entered using EPI-DATA version 4.2.0.0, and analyzed using SPSS version 20 statistical software.
of the 453 participants, 177 (39.1%) had good knowledge about STIs. The study recommended. In addition, inculcating the sexual and reproductive health course in the educational curriculum plays a paramount importance.Thyroid abscess is an extremely rare condition. Its diagnosis is often late, which predisposes to serious complications. We report a case of thyroid abscess in a young adult who presented to the emergency room for a basi-cervical swelling associated with dysphonia, dysphagia and dyspnea. Neck ultrasound showed a collection of left thyroid lobe. A cervicothoracic computed tomography objectified an abcess of the left lobe of the thyroid fistulising in the hyoid muscles beneath and left piriform sinus with thickening of the hypopharynx and upper esophageal sphincter. The puncture brought a purulent fluid. Panendoscopy revealed the presence of a tumor proliferation of the upper esophageal sphincter. A biopsy with histological examination concluded to a squamous cell carcinoma. this website This observation indicates that the thyroid abscess may be the mode of discovery of esophageal cancer. Hence the interest to seek an underlying cause in cases of thyroid abscess.Rupture of Valsalva sinus remains a very rare and deadly complication of Valsalva sinus aneurysm with a high mortality rate. We report here the case of a 47-year-old man who presented to the emergency department with acute exercise-induced dyspnea, chest pain, and fever. Transthoracic (TTE) and transesophageal echocardiography (TEE) highlighted a rupture of the right Valsalva sinus in the right atrium due to infective endocarditis. After stabilization of the patient, a successful surgical repair with double pericardial patches was performed.
the Global-Partnership-Initiated-Biosecurity-Academia for Controlling Health Threats (GIBACHT) consortium conducts a biosafety and biosecurity training for fellows from Africa, the Middle East and Asia. To achieve a multiplier effect, fellows conduct trainings in their own organizations. It was during such trainings that training needs assessments were done assessing reasons for and barriers to biosafety and biosecurity training.
this was a cross sectional assessment. Trainings were conducted from April to July 2018 and April to June 2019. In 2018, training needs were explored using a structured tool. Responses were coded using manifest content analysis and key issues identified. In 2019, respondents quantified the identified key issues using a Likert scale. Proportions of those who strongly agreed, agreed, neither agreed nor disagreed, disagreed or strongly disagreed were calculated and results presented in tables and charts.
in 2018 and 2019, there were 183 and 191 respondents respectively. About 96% of respondents in 2018 supported training in biosafety and biosecurity citing individual, community and global benefits.
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