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Epidemiological, Scientific and Research laboratory Characteristics of Individuals along with Brucella Infection within Anhui Domain, The far east.
To assess the frequency and characteristics of headache in patients with COVID-19 and whether there is an association between headache and anosmia and ageusia.

This was a cross-sectional study. Consecutive patients admitted to hospital with COVID-19, confirmed by reverse transcription polymerase chain reaction (RT-PCR) technique, were assessed by neurologists.

Seventy-three patients were included in the study, 63% were male; the median age was 58 years (IQR 47-66). Forty-seven patients (64.4%) reported headaches, which had most frequently begun on the first day of symptoms, were bilateral (94%), presenting severe intensity (53%) and a migraine phenotype (51%). Twelve patients (16.4%) presented with headache triggered by coughing. Eleven (15%) patients reported a continuous headache. Twenty-eight patients (38.4%) presented with anosmia and 29 (39.7%) with ageusia. Patients who reported hyposmia/anosmia and/or hypogeusia/ageusia experienced headache more frequently than those without these symptoms (OR 5.39; 95% CI1.66-17.45; logistic regression). Patients with anosmia and ageusia presented headache associated with phonophobia more often compared to those with headache without these complaints (Chi-square test;
 < 0.05). Headache associated with COVID-19 presented a migraine phenotype more frequently in those experiencing previous migraine (
 < 0.05).

Headaches associated with COVID-19 are frequent, are generally severe, diffuse, present a migraine phenotype and are associated with anosmia and ageusia.
Headaches associated with COVID-19 are frequent, are generally severe, diffuse, present a migraine phenotype and are associated with anosmia and ageusia.New daily persistent headache was first documented in the medical literature in the 1980s. The leading trigger is a viral illness. As we navigate our way thru the current SARS-CoV-2 pandemic, looking back at past viral epidemics may help guide us for what to expect in the near future in regard to headaches as a persistent manifestation of the SARS-CoV-2 infection. The 1890 viral pandemic known as the "Russian or Asiatic flu", has extensive documentation about the neurologic sequelae that presented months to years after the pandemic ended. One of the complications was daily persistent headache. There are actually many similarities between the viral presentation of the 1890 pandemic and the current SARS-CoV-2 pandemic, which may then suggest that not only will NDPH be part of the neurological sequelae but a possible key consequence of the SARS-CoV-2 infection.Compositions of volatile oil from Lagerstroemia indica L. were reported for the first time. Out of 114 components where 58, 63, 67 and 61 compounds were identified from the white, pink, mauve, carmine flower with yields of 0.92%, 1.15%, 1.12% and 1.08%, respectively. Main compounds of white flower were 2-methyl-cyclopentanone (9.41%), m-xylene (7.53%) while the pink, carmine flower contained octacosane (19.81% and 13.91%) and heneicosane (18.02% and 7.98%), respectively, and mauve flower contained cyclohexanone (8.13%), 1-octacosanol (7.87%). Only 23 components were common in four oils, representing 16.57-32.72% of the total oils. Composition classification of four oils included mainly alkanes, benzenes, ketones with 52.98-73.03% of the total oils. see more The results revealed the different characteristics in quality of these oils. The pink, mauve, carmine flower oils were found active against S. aureus and A. niger, P. aeruginosa and S. aureus, E. coli and B. subtilis with MIC value of 0.078 mg/mL.LC-HR-MS-coupled metabolic profiling of the methanol extracts from different parts of Syzygium cumini (L.), which was extensively identified via DNA fingerprinting, led to dereplication of 24 compounds. Cytotoxic investigation highlighted both extracts as the most potent, against both MCF-7 and MDA-231 Cell lines, with IC50 value of 5.86 ± 0.63 µg/ml and against HCT -116 cell line, with IC50 value of 1.24 ± 0.09 µg/ml, respectively. A molecular docking study was performed on the dereplicated compounds, which highlighted myricetin-3-glucoside (7), myricitrin (12), reynoutrin (15) and quercitrin (16) as the top scoring ligands within the protein active site (FIH-1). Interestingly, the extracts were significant against streptozotocin-induced diabetes in the order of flowers > seeds > leaves with BGL level of 98.9 ± 4.3, 123.2 ± 4.9 and 132.8 ± 5.9 mg/dl, respectively. The study highlights the health benefits of Syzygium cumini (L.) as a promising cytotoxic source.Vibrio parahaemolyticus, Vibrio cholerae and Vibrio vulnificus are the most significant aquatic pathogens of the genera Vibrio, account for most Vibrio-associated outbreaks worldwide. Rapid identification of these pathogens is of great importance for disease surveillance, outbreak investigations and food safety maintenance. Traditional culture dependent methods are time-consuming and labor-intensive whereas culture-independent polymerase chain reaction (PCR) based assays are reliable, consistent, rapid and reproducible. This review covers the recent development and applications of PCR based techniques, which have accelerated advances in the analysis of nucleic acids to identify three major pathogenic vibrios. Emphasis has been given to analytical approaches as well as advantages and limits of the available methods. Overall, this review article possesses the substantial merit to be used as a reference guide for the researchers to develop improved PCR based techniques for the differential detection and quantification of Vibrio species.This study aimed at evaluating the impact of environmental factors on the accumulation of various components in Hedera helix L. folium collected from different European countries. The obtained results of studied samples showed that the antioxidant capacities were in the range of 0.027 to 0.688 mg/g. Contents of active components varied phenolic acids - from 0.033 up to 2.92 gallic acid equivalents mg/g, flavonoids - from 0.031 to 0.281 mg/g and hederacoside C - 13.54-109.458 mg g-1 DW. Samples from the northern countries had higher amounts of all phytochemicals in comparison to the southern ones. Among all studied parameters, the duration of sunshine, soil and climate had the most significant influence on the accumulation of components in ivy raw materials while altitude and precipitations showed none impact. Hedera helix can be considered as an excellent source of triterpene saponins, flavonoids and phenolic acids, and growing it at the right conditions may significantly enhance the quality of its raw material for medicinal purposes.
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