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Study on the strategy involving enucleation of anterior uterine fibroids by transversus incision from the reduce uterine part in the course of cesarean section.
Conclusions These two studies indicate reproducible donor-dependent differences in transfused platelet recovery, suggesting a possible heritable influence on the quality of transfused platelets.Background and objectives Irreversible electroporation (IRE) is a nonthermal electrical tumor ablative strategy for unresectable tumors. IRE is relatively safe around critical structures but may induce cardiac arrhythmia when its delivery is not synchronized to the cardiac cycle. We performed a systematic literature review to determine rates of arrhythmia when IRE was utilized with or without cardiac synchronization. Methods An online literature search was conducted with additional hand selection of articles. Data were extracted and pooled analyses were performed. Results Twelve articles were included in analysis. IRE was performed for 481 patients; 46% hepatic tumors (n = 223), 36% pancreatic lesions (n = 168), and multiple other locations including prostate. find more Synchronization was performed on 422 patients. Arrhythmias were noted in 3.7% of cases (n = 18/481); cardiac synchronization 1.2% (n = 5/422) vs unsynchronized 22.0% (n = 13/59), P less then .0001. These events occurred in every organ except the prostate. Conclusions IRE remains a potent technology for unresectable tumors, but arrhythmia is a clinical concern. This literature review confirms that cardiac gating should be used in all cases outside of prostate to prevent this potentially serious adverse event.Fifteen years ago, Ruth Macklin shook the medical community with her claim in the BMJ that dignity is a useless concept. Her essay provoked a storm of reactions. What have we learned from the debate? In this article I analyse the responses to her essay and the following debate to investigate whether she was right that "[d]ignity is a useless concept in medical ethics and can be eliminated without any loss of content." While some of the commentaries misconstrued her claim and argue against strawmen, others forcefully maintained that the concept of dignity has functions beyond "respect for persons and their autonomy." One important point that came out of the debate is that dignity is a generic concept that covers more ground than "respect for persons or their autonomy." In particular, dignity seems to have a wide range of protective functions as well as having reciprocal, relational, and social aspects. Dignity appears more attributional and norm-formative than respect for persons and autonomy. While the claim that dignity is unclear, vague, and can be used sloganistically seems highly relevant, it is argued that this vagueness fulfils important functions in ethics. Moreover, dismissing dignity because of its lack of clarity has implications for "respect for persons" and "autonomy," which are also used vaguely and sloganistically. No doubt medical ethics should use as a clear concept as the context requires. Nonetheless, dignity still seems to be a widely used generic concept in ethical debates and doing as much ethical work as "respect for persons" or "respect for autonomy." Therefore, the death of dignity seems to be greatly exaggerated.Drawing from theory on the "co-production" of science and society, this paper provides an account of trajectories in US climatology, roughly from the 1850s to 1920, the period during which climatology emerged as an organized branch of meteorology and government administration. The historical narrative traces the development of climatology both as a professional/institutional project and as a component of a larger governmental logic. Historical analysis of climatologists' scientific texts, maps, and social organization within government provides a sociological explanation for the emergent "stabilization" of climate as a geographic-statistical category. Climatic stability, defined by the view that climate is unchanging, was advanced over this period in a way that linked the interests and practices of climatologists to actors invested in facilitating and administrating commercial agriculture and trade. I position the logic of climatology and the discourse of climatic stability historically, with reference to prior concern with climate change and, in recent decades, efforts to govern global warming through geoengineering climatic stability.We recently enjoyed the article entitled published from Kyoto group (1) with much interest. They evaluated muscle mass index (MSI) and intramuscular adipose tissue content (IMAC), representing muscular mass and quality respectively, and fond that high muscularity donor with higher SMI and lower IMAC for age-adjusted values was the independent positive factor for survival.Dental pulp engineering possesses a promising perspective to replacing lost pulp in the root canal and restoring its functions. Stable adhesion of dental pulp stem cells (DPSCs) on the root canal dentin wall is a key element required for reconstruction of a functional odontoblast layer in dental pulp regeneration. To address this challenge, dopamine-modified hyaluronic acid (DA-HA) is coated on dentin to obtain a stable adhesion of DPSCs. The dopamine segment provides adhesion ability to the coating, and the hyaluronic acid increases the biocompatibility. The results show that DPSCs can adhere on the DA-HA coated dentin slice better than those without coating. Simultaneously, DPSCs proliferation can be further promoted on the prepared coating. Therefore, the DA-HA coating may provide a possible way to immobilize odontoblast cell onto dentin surface for pulp regeneration.Introduction Our aim in this study was to identify the prevalence and clinical characteristics of LRP4/agrin-antibody-positive double-seronegative myasthenia gravis (DNMG). Methods DNMG patients at 16 sites in the United States were tested for LRP4 and agrin antibodies, and the clinical data were collected. Results Of 181 DNMG patients, 27 (14.9%) were positive for either low-density lipoprotein receptor-related protein 4 (LRP4) or agrin antibodies. Twenty-three DNMG patients (12.7%) were positive for both antibodies. More antibody-positive patients presented with generalized symptoms (69%) compared with antibody-negative patients (43%) (P ≤ .02). Antibody-positive patients' maximum classification on the Myasthenia Gravis Foundation of America (MGFA) scale was significantly higher than that for antibody-negative patients (P ≤ .005). Seventy percent of antibody-positive patients were classified as MGFA class III, IV, or V compared with 39% of antibody-negative patients. Most LRP4- and agrin-antibody-positive patients (24 of 27, 89%) developed generalized myathenia gravis (MG), but with standard MG treatment 81.
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