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all approach, this digital platform should aid the matchmaking between patients and specific interventions based on personal characteristics and preferences.
Various stakeholders in the field of cardiovascular prevention and rehabilitation may benefit most from utilizing one personalized eHealth platform that integrates a variety of evidence-based interventions, rather than a new tool. Instead of a one-size-fits-all approach, this digital platform should aid the matchmaking between patients and specific interventions based on personal characteristics and preferences.Along with rising levels of the infection around the world, the state of emergency prompted by the COVID-19 pandemic has also been having a heavy legal impact. The situation is posing important criminal challenges, as well as an ocean of social and public health issues around the world. It has not only directly affected constitutionally-guaranteed rights and individual freedoms, but also brought to the fore certain types of criminal offence that had previously been of little practical importance, such as the crime of 'maliciously or unintentionally causing an epidemic'. Different countries and states have introduced policies to manage the emergency at different times and in different ways. The measures adopted have been the object of much criticism, also raising questions of constitutional legitimacy in countries like Italy. The present contribution begins with a brief outline of the different international scenarios. Then we examine some of the medicolegal aspects of criminal offences previously envisaged and newly introduced since the arrival of the pandemic. We suggest the need for a sort of 'code of public health laws for the time of coronavirus', that could also be applied to other public health emergencies, pandemic or otherwise. The idea is to give operators in the sector and the general population the opportunity to identify clear and simple rules to follow in the current complex global situation. We need a new, appropriate interpretation of the 'boundaries' of our individual rights in relation to the need to safeguard the wider community and its more vulnerable members.Reservoirs are a significant source of the potent greenhouse gas nitrous oxide (N2O), but there are few data on N2O in the world's largest reservoirs and limited understanding of the factors controlling their emission rates. Here we analyzed high-resolution measurements of dissolved N2O concentrations and fluxes in a typical tributary bay of Three Gorges Reservoir. The surface water was oversaturated in N2O during both low and high water level (8.6 -16.4 nmol/L, 107% - 180% saturation) and N2O fluxes varied nearly tenfold (0.2 and 1.6 μmol/(m2 h)). Dissolved N2O concentrations were characterized by pronounced vertical gradients, which were controlled by bidirectional density currents. The river water with high concentrations entered the bay as an underflow along the riverbed, the upper part of the water column was formed by intrusive backwater of Three Gorges Reservoir having significantly lower N2O concentrations. In consequence, the N2O emission potential of the impoundment was reduced compared to pre-impoundment conditions. These results reveal the importance of hydraulic conditions on N2O emission from large reservoirs and suggest that flow regulation can be a potential tool for mitigating greenhouse gas emissions from manmade impoundments.Nitrate, arsenic and fluoride are some of the most hazardous elements contaminating groundwater resources. In this work, the impact of operative (flowrate, electricpotential) and water quality (salinity, contaminant feed concentration, pH) parameters on brackish water decontamination was investigated using a batch electrodialysis (ED) system. Electrodialysis at low electric potentials (5 V) was more selective toward monovalent ions, at higher potentials (>15 V) removal of all ions increased and selectivity approached one, meaning removal of all ions. Changing the flowrate from 30 to 70 L/h, increased nitrate and fluoride removal slightly, while arsenic(V) removal was maximum at 50 L/h. Rising salinity delayed removal of ions with low ionic mobility and diffusivity (i.e. fluoride, arsenic(V)). Increased feed concentration of contaminants had no impact on removal values. pH variations did not impact the nitrate, fluoride and salinity removal, yet arsenic(V) removal was greatly pH dependent. This was explained in part by lower diffusivity and higher hydration number of bi- and trivalent species of arsenic(V) at basic pH. The results of this work showed the significance of ionic characteristics (diffusivity, ionic mobility, hydration number) in ED. Nitrate concentrations satisfied guideline threshold in all experiments with concentrations below 50 mg/L. Lowest arsenic(V) concentration was 35 µg/L at the highest electric potential, 25 V. Using ionic characteristics makes separation of different ions possible, providing new opportunities for ED in environmentally friendly processes (e.g. Akt inhibitor resource recovery and zero liquid discharge).Dissolved organic matter (DOM) plays a crucial role in the photochemical transformation of organic contaminants in natural aquatic systems. The present study focuses on the characterization of a specific effect previously observed for electron-rich phenols, consisting in an acceleration of the DOM-photosensitized transformation of target compounds at low concentrations ( less then 1 µM). This effect was hypothesized to be caused by DOM-derived "long-lived" photooxidants (LLPO). Pseudo-first-order rate constants for the transformation of several phenols, anilines, sulfonamide antibiotics and phenylureas photosensitized by Suwannee River fulvic acid were determined under steady-state irradiation using the UVA and visible wavelengths from a medium-pressure mercury lamp. A significant enhancement (by a factor of 2.4 - 16) of the first-order transformation rate constant of various electron-rich target compounds was observed for an initial concentration of 0.1 μM compared to 5 μM . This effect points to a relevant reactivity of these compounds with LLPO. For phenols and anilines the enhancement effect occurred only above certain standard one-electron oxidation potentials. From these data series the standard one-electron reduction potential of LLPO was estimated to be in the range of 1.0 - 1.3 V versus the standard hydrogen electrode. LLPO are proposed to mainly consist of phenoxyl radicals formed by photooxidation of electron-poor phenolic moieties of the DOM. The plausibility of this hypothesis was successfully tested by studying the photosensitized transformation kinetics of 3,4-dimethoxyphenol in aqueous solutions containing a model photosensitizer (2-acetonaphthone) and a model electron-poor phenol (4-cyanophenol) as DOM surrogates.
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