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The arsenic hyperaccumulating Pteris vittata conveys 2 arsenate reductases.
The discovery of selection signatures has enabled the identification of genomics regions under selective pressure, enhancing knowledge of evolutionary genotype-phenotypes. Sex chromosomes play an important role in species formation and evolution. Therefore, the exploration of selection signatures on sex chromosomes has important biological significance.

In this study, we used the Cross Population Extend Haplotype Homozygosity Test (XPEHH), F-statistics (F
) and EigenGWAS to assess selection signatures on the Z chromosome in 474 broiler chickens via Illumina chicken 60 K SNP chips. SNP genotype data were downloaded from publicly available resources. We identified 17 selection regions, amongst which 1, 11 and 12 were identified by XPEHH, F
, and EigenGWAS, respectively. Each end of the Z chromosome appeared to undergo the highest levels of selection pressure. A total of 215 candidate genes were located in 17 selection regions, some of which mediated lipogenesis, fatty acid production, fat metabolism, and fat decomposition, including FGF10, ELOVL7, and IL6ST. Using abdominal adipose tissue expression data of the chickens, 187 candidate genes were expressed with 15 differentially expressed genes (DEGs) in fat vs. lean lines identified. Amongst the DEGs, VCAN was related to fat metabolism. GO pathway enrichment analysis and QTL annotations were performed to fully characterize the selection mechanism(s) of chicken abdominal fat content.

We have found some selection regions and candidate genes involving in fat metabolism on the Z chromosome. learn more These findings enhance our understanding of sex chromosome selection signatures.
We have found some selection regions and candidate genes involving in fat metabolism on the Z chromosome. These findings enhance our understanding of sex chromosome selection signatures.Background As a result of the Fukushima Daiichi nuclear power plant accident, many residents evacuated and were exposed to changes in their living environment and socioeconomic status, and to persistent stressors. Past studies have suggested the potential for these circumstances to contribute to long-term changes to population health.Objective The objective of this study was to gain a better understanding of long-term health effects of evacuation, by evaluating the risk of non-communicable diseases among evacuees from Minamisoma City (one of the closest municipalities to the power plant) until 2017.Methods The study evaluated data from annual health check-ups for residents aged 40-74 years covered by National Health Insurance (who are largely self-employed) from 2010 to 2017 administered by Minamisoma City. Diabetes, hyperlipidemia, and hypertension were defined from the results of blood sampling. Annual changes in age-adjusted prevalence were estimated by evacuation scenario. We also performed an inverse-proass evacuation.Georg Ernst Stahl, an influential chymical-medical author of the late seventeenth and early eighteenth centuries, first believed in alchemical transmutation and reversed his position over the course of his career. This essay begins by placing Stahl's early teaching in alchemy in a larger background in which German princes and academics shared intense interest in gold-making. Then, tracing Stahl's intellectual development, it shows that he developed an increasing reservation about alchemy, though he remained open to the possibility of transmutation during his tenure at Halle. Finally, this essay shows that Stahl's service to King Friedrich Wilhelm I was an important context for his later public denunciation of alchemy. An analysis of Stahl's career shift from a university professor to a royal physician at court thus sheds light on the reversal of his positions.There are few apparent studies regarding the association between fine particulate matter (PM2.5) air pollution and development of depression. Data obtained from epidemiological studies are inconsistent and controversial. The aim of this case-crossover study was to examine the association between short-term exposure to PM2.5 alone and in combination with other pollutants and frequency of hospitalizations for depression from 2009 to 2013 in Taipei, Taiwan. In the single pollutant model without adjustment for other pollutants, 17% and 4% increase in admissions attributed to depression correlated with interquartile range (IQR) rise in PM2.5 levels was noted on warm and cool days, respectively. Data were also analyzed using two-pollutant models and it was found that on warm days, the association continued to be significant after including one of the following pollutants sulfur dioxide (SO2), nitrogen dioxide (NO2), ozone (O3) or carbon monoxide (CO). On cool days, the significance was lost. In conclusion, the relationship between ambient outdoor PM2.5 exposure and rates of hospitalization for depression appeared to be temperature dependent in Taipei. Further research is needed to verify these observations as well as to distinguish the relative contributions of PM2.5 and temperature to development for hospital admissions for depression.We know that performing simultaneous cognitive tasks during locomotion results in reduced performance on either or both tasks, however the role of the cognitive system in the execution of last-minute changes to ongoing adaptive locomotor tasks is not fully understood. Nineteen participants were initially cued to circumvent to left, right, or step over an obstacle while an auditory cognitive task was simultaneously presented. In half of the trials, no change in avoidance strategy was required; in the remaining trials, participants were visually cued two steps in advance to execute a new circumvention strategy. Participants decreased gait velocity and increased cognitive task response times when executing changes in strategy, highlighting the important role the cognitive system plays in these complex tasks.This study examined the moderating influence of resilience on the association between emotional intelligence and work engagement in clinical leaders. The study population was leaders working in the emergency wards of some health facilities in Accra. link2 A total of 310 leaders participated in the study by completing a self-reported questionnaire. The analysis of data showed that emotional intelligence makes a positive influence on work engagement in clinical leaders working in emergency departments. The moderating influence of Health facilities can improve work engagement in emergency settings by utilizing training programs to improve both emotional intelligence and resilience.We aimed to identify the prevalence of SARS-CoV2 and its related factors among suspected health sector workers (HSWs) by conducting a descriptive analytical study on the SARS-CoV2 registered data in Shahroud region, Iran. link3 Among the 267 suspected HSWs, 15.7% were confirmed vs. 29.1% of the suspected non-HSW cases, and the difference between two groups was significant. Among the related variables, after adjusting for age and sex, being asymptomatic (OR = 0.43), having fever (OR = 3.28), inpatient (OR = 7.14), and no history of flu vaccination (OR = 2.33) were significantly associated with the confirmed HSWs. It is recommended that all HSWs be screened and close contacts of confirmed cases be followed up.This research examined determinants of self-rated health (SRH) of publicly funded home-and-community-based services (HCBS) recipients and tested if the effects of determinants differ between older recipients and younger recipients with disabilities. Using Minnesota's data of 2015-2016 National Core Indicators - Aging and Disabilities survey (n = 3,426), this study revealed that functional status and community inclusion had both direct and indirect effects on SRH, with negative mood as a mediator. Community inclusion had a more pronounced effect on SRH in younger recipients than in older recipients. HCBS should address psychosocial needs and be tailored for recipients of different age groups.The chair of chymiatria created at the University of Marburg was among the earliest academic initiatives aiming to integrate chymistry into the medical curriculum. If its practical applications in pharmacy and its relationship with patronage have been examined by historians, the theoretical part of the chymiatria programme still remains to be explored. In the form of student disputations and dissertations held or presided over by Heinrich Petraeus, a professor of medicine at Marburg and Johannes Hartmann's son-in-law, "chymiatric" essays expounded various medical issues. Centred on pathology, therapy, and physiology, these theoretical explanations proposed a "hermetic-dogmatic" interpretation merging the views of Paracelsus and Galen. This article examines these disputations and their stance concerning the living body, sickness, and treatment, and how they shaped the status of chymistry as an art and a science on the verge of institutionalisation.Massive rural-to-urban migration in China has a significant impact on informal caregiving arrangements among Chinese older adults. To stimulate research on the intersection of migration and caregiving, we conducted an inventory of longitudinal aging survey datasets from mainland China. Large publicly available datasets that included measures related to migration and caregiving were searched and reviewed for eligibility. Key characteristics of each dataset, including study design, sample size, and measures, were extracted. Seven eligible datasets were identified, and five included nationally representative samples. Measures for migration varied across datasets. Some datasets included information on the migration history of older adults, whereas others focused on the migration of adult children. Similarly, caregiving was measured using different questions in each dataset. Caregiving activities were assessed with regard to their type, source, and amount. High-quality datasets exist to support research on migration and caregiving arrangements among Chinese older adults.Greenlandic traditional nutrition was unique in the arctic environment because it was an almost exclusive meat dietary pattern. Høygaard et al. left Copenhagen in August 1936, and stayed in East Greenland until August 1937. The four members of the expedition resided in Tasisaq and visited eight settlements around where nutritional intake was recorded by residing in families. However, the nutritional intake was analysed on a household level. The aim of the present study is to reanalyse the Høygaard et al. data according to modern scientific standards.In total, 21 males and 14 females participated. Median (IQR) energy consumption was 3881 (1568) kcal.day-1 for males and 2910 (882) kcal.day-1 for females. Without the five participants living near trading centres, this was 3268 (219) kcal.day-1 and 2634 (723) kcal.day-1, respectively. Expressed in energy-percent, the macronutrient consumptions were 34% for protein, 37% for fat and 29% for carbohydrates. Without imported food, this was 41%, 49% and 10%, respectively.The main findings of the present study are, as expected, that the food consumed came mainly from traditional hunting, was low in plant foods and extremely low in carbohydrates. The Inuit succeeded to stay in apparently healthy conditions with a traditional meat-based dietary pattern.
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