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Microwave-assisted pyrolysis involving oily sludge from ocean going oilfield with regard to healing of high-quality products.
The shaping of metal-organic frameworks (MOFs) has become increasingly studied over the past few years, because it represents a major bottleneck toward their further applications at a larger scale. MOF-based macroscale solids should present performances similar to those of their powder counterparts, along with adequate mechanical resistance. Three-dimensional printing is a promising technology as it allows the fast prototyping of materials at the macroscale level; however, the large amounts of added binders have a detrimental effect on the porous properties of the solids. Herein, a 3D printer was modified to prepare a variety of MOF-based solids with controlled morphologies from shear-thinning inks containing 2-hydroxyethyl cellulose. Four benchmark MOFs were tested for this purpose HKUST-1, CPL-1, ZIF-8, and UiO-66-NH2. All solids are mechanically stable with up to 0.6 MPa of uniaxial compression and highly porous with BET specific surface areas lowered by 0 to -25%. Furthermore, these solids were applied to high-pressure hydrocarbon sorption (CH4, C2H4, and C2H6), for which they presented a consequent methane gravimetric uptake (UiO-66-NH2, ZIF-8, and HKUST-1) and a highly preferential adsorption of ethylene over ethane (CPL-1).Facile fabrication of multifunctional porous inorganic aerogels remains an outstanding challenge despite the considerable demand for extensive applications. Here, we present the production of a multifunctional porous inorganic nanomaterial aerogel by controllable surface chemistry of a functionalized SWNT (fSWNT) hydrogel platform for the first time. The versatile functional inorganic nanoparticles can be incorporated uniformly on the porous 3D fSWNT hydrogel platform through a facile dip coating method at ambient conditions. The morphology of the multifunctional inorganic aerogel is manipulated by designing the fSWNT hydrogel platform for different requirements of applications. In particular, Pt-SnO2@fSWNT aerogels exhibit high porosity and uniformly distributed ultrafine Pt and SnO2 on the fSWNT platform with controllable particle size (1.5-3.5 nm), which result in significantly high surface area (393 m2 g-1). The ultrafine Pt-SnO2@fSWNT aerogels exhibit highly sensitive (14.77% at 5 ppm) and selective NO2 sensing performance even at room temperature due to the increased active surface area and controllable porous structure of the ultrafine aerogel, which can provide fast transport and penetration of a target gas into the sensing layers. The newly designed multifunctional inorganic aerogel with ultrahigh surface area and high open porosity is a prospective materials platform of high performance gas sensors, which could be also broadly expanded to widespread applications including catalysis and energy storages.Cocaine dependence displays a broad impairment in cognitive performance including attention, learning, and memory. To obtain a better understanding of the action of cocaine in the nervous system, and the relation between phospholipids and memory, we have investigated whether phospholipids recover in the brain following cocaine removal using the fly model, Drosophila melanogaster. In addition, the effects of methylphenidate, a substitute medication for cocaine dependence, on fly brain lipids after cocaine abuse are also determined to see if it can rescue the lipid changes caused by cocaine. Time of flight secondary ion mass spectrometry with a (CO2)6000+ gas cluster ion beam was used to detect intact phospholipids. We show that cocaine has persistent effects, both increasing and decreasing the levels of specific phosphatidylethanolamines and phosphatidylinositols. These changes remain after cocaine withdrawal and are not rescued by methylphenidate. Cocaine is again shown to generally increase the levels of phosphatidylcholines in the fly brain; however, after drug withdrawal, the abundance of these lipids returns to the original level and methylphenidate treatment of the flies following cocaine exposure enhances the reversal of the lipid level reducing them below the original control. The study provides insight into the molecular effects of cocaine and methylphenidate on brain lipids. We suggest that phosphatidylcholines could be a potential target for the treatment of cocaine abuse as well as be a significant hallmark of cognition and memory loss with cocaine.Tumor targeting provided more effective gene therapy. Bcl-2 is an oncogene, and Bcl-2 small interfering RNA (Bcl-2 siRNA) can inhibit its expression. Here, a fluorescent and gene-loading capacity vector DPL, derived from diketopyrrolopyrrole (DPP), was developed for Bcl-2 siRNA-targeted delivery and tumor imaging in vitro and in vivo. The vector DPL showed a significant emission enhancement after interacting with siRNA, which was used to track the gene transfer process. Compared to commercial transfection reagent Lipo 2000, DPL obviously downregulated the Bcl-2 protein expression and exhibited excellent antitumor efficacy with less Bcl-2 siRNA. Importantly, DPL can target tumors to transport Bcl-2 siRNA to tumor sites in vivo based on the enhanced permeability and retention (EPR) effect for effective in vivo tumor therapy. This work inspired us to design and synthesize a multifunctional gene vector for tumor targeting and gene therapy.Graphene oxide (GO)-based membranes have displayed superior performances in the chiral resolution compared with conventional polymer-based and inorganic membranes. However, the effect of the host-guest interaction between chiral selectors and probes on the enantioseparation properties of GO-based membranes remains to be established. buy E7080 In this work, l-phenylalanine (l-Phe, as the chiral selector)-modified GO-based (l-Phe-GO) membranes were fabricated, and their enantioseparation performances toward various enantiomers, that is, d- and l-phenylalanine (d- and l-Phe), d- and l-methionine (d- and l-Met), N-acyl-d-phenylalanine (N-acyl-d-Phe) and N-acyl-l-phenylalanine (N-acyl-l-Phe), and N-acyl-d-methionine (N-acyl-d-Met) and N-acyl-l-methionine (N-acyl-l-Met), were detected. Results show that (i) l-Phe is preferential to transport d-enantiomers relative to l-enantiomers; (ii) as far as d-enantiomers are concerned, the d-Phe-like enantiomers move faster than d-Met-like ones through the l-Phe-GO membrane owing to their different host-guest interactions.
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