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PURPOSE To explore the effect of sodium fluoride tooth protector combined with pit and fissure sealing to prevent caries in preschool children. METHODS Two hundred preschool children who were treated with pit and fissure closure from January 2014 to September 2014 were selected as subjects. According to random number table method, 100 cases were divided into the combined group and the control group. Children in the control group were treated with pit and fissure sealant for prevention of caries, while children in the combined group were treated with sodium fluoride tooth protector combined with pit and fissure sealant for caries prevention. The incidence of dental caries, proximal caries, mean DMFT, and expulsion rate of the sealants were compared between the two groups at 1 year and 2 years. Data analysis was performed using SPSS 16.0 software package for data analysis. RESULTS At 1 year of follow-up, there was no significant difference in the incidence of dental caries, proximal caries, and mean DMFT between the two groups (P>0.05). The incidence of caries and mean DMFT in the combined group were significantly lower than those in the control group at 2 years of follow-up (P0.05). CONCLUSIONS Sodium fluoride tooth protector combined with pit and fissure sealing has better anti-caries effect than the use of pit and fissure sealant alone in preschool children.PURPOSE To investigate the effect of single low level laser therapy on initial pain during fixed orthodontic treatment. METHODS Sixty patients who underwent fixed orthodontic treatment in our hospital from January 2015 to December 2017 were enrolled.Patients were divided into 2 groups by random number table method, 30 in each group. Patients in the experimental group were treated with a single low level laser therapy ,while patients in the control group were treated with a placebo.The results of the 2 groups were compared in regard to spontaneous pain and chewing pain during the day and night using SPSS 22.0 software package. RESULTS Spontaneous pain during day and night with 0.012, 0.014 inch superelastic nickel-titanium (NiTi) line was significantly lower in the experimental group than in the control group(P0.05).Chewing pain with 0.012, 0.014, 0.016, and 0.018 inch NiTi lines in the experimental group was significantly lower than that in the control group(P less then 0.05). CONCLUSIONS Single low level laser therapy significantly reduced postoperative pain while placing a superelastic NiTi wire for initial alignment and correction.PURPOSE To assess the relation of oral health knowledge, attitude and practice(KAP) of the students aged 12-15 in Shanghai, and provide data support for intervention strategies of oral health. METHODS A total of 2927 subjects aged 12-15 years old were selected according to the method of the Fourth National Oral Health Epidemiological Survey and the questionnaire was filled. SAS 9.4 software package was used for statistical analysis. RESULTS The subjects were divided into 2 categories according to their knowledge and attitude of oral prevention and oral health. TypeⅠgroup, with high cognitive attitude, had more teeth brushing times than those of typeⅡgroup with poor cognitive attitudes(P less then 0.01). TypeⅠgroup had more people knowing and using toothpaste with fluoride. (P less then 0.01). The frequency of type I group using dental floss was significantly higher than typeⅡgroup(P less then 0.01), while the frequency of having deserts was relatively lower than typeⅡgroup (P less then 0.01), and the frequency of having drinks was lower than type Ⅱ(P less then 0.01). The two groups had no significant difference in the frequency of consumption of other drinks with sugar ( P=0.11). CONCLUSIONS Oral related risk behaviors are quite common among 12-15 years students in Shanghai, which are closely related to the knowledge and attitude.PURPOSE To study the difference between the distinct ways of delivering postoperative instructions to reduce the side effects of wisdom tooth extraction, including pain, bleeding and swelling, and improve the degree of satisfaction of the patients. METHODS A group of 150 patients who underwent wisdom tooth extraction in the Department of Oral and Maxillofacial Surgery of Xiangya Hospital, Central South University between Jan. 2018 to Oct. 2018 were selected in this research randomly. They were divided into 3 groups randomly and 50 patients in each group. Patients in group 1 received verbal postoperative instructions, patients in group 2 received written postoperative instructions, and patients in group 3 received verbal plus written postoperative instructions. The information of age, sex and education level was collected for each patient. The side effects of pain, bleeding and swelling, and the satisfactory degree of the patients were recorded 7 days after surgery. SPSS 22.0 software package was used for statistical analysis. RESULTS There were 81 women and 69 men among 150 patients. The mean age was 24.6±2.6 years. The results showed that the degree of pain of group 1 was significantly higher than group 2 (P=0.001) and group 3 (P=0.000). The satisfactory degree of group 1 was the lowest, and group 3 was the highest. CONCLUSIONS The way of delivering postoperative instructions affects pain and satisfactory degree after wisdom tooth extraction.PURPOSE To investigate the independent prognostic factors and establish survival prediction model for advanced oral squamous cell carcinoma (OSCC). METHODS At the time of admission, the general information and past medical history of 177 patients with advanced OSCC were collected in detail. All patients underwent radical resection. After surgery, radiotherapy and chemotherapy with hydroxycampothecin (HCPT) and pingyangmycin (PYM) were performed according to the patient's condition. All patients were followed up for 5 years after surgery, and the survival rate during that period and the risk factors for prognosis were analyzed. The data were analyzed by SPSS 20.0 software package. selleck chemical RESULTS During the follow-up period, 2 patients died due to other causes, 4 were excluded due to lost to follow-up, 42 of the remaining 111 patients died, 69 survived, the total survival rate was 62.16%. The survival status of patients with advanced OSCC with different age, T stage and M stage had no significant difference (P>0.05), while significant difference was found among patients with different gender, tissue differentiation degree, N stage and chemotherapy (P0.
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