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Accuracy was lower in the backward/carryover direction, and although agreement and consistency were still reasonably high across perceivers, the effect of age group differed between the laboratory and online environments, suggesting measurement error in one or both environments. Overall, the results support using in-lab or online perceptual judgments to measure anticipatory coarticulation in developmental studies of speech production. Further validation study is needed before the method can be extended to measure carryover coarticulation.A consensus on the importance of open data and reproducible code is emerging. How should data and code be shared to maximize the key desiderata of reproducibility, permanence, and accessibility? Research assets should be stored persistently in formats that are not software restrictive, and documented so that others can reproduce and extend the required computations. The sharing method should be easy to adopt by already busy researchers. We suggest the R package standard as a solution for creating, curating, and communicating research assets. The R package standard, with extensions discussed herein, provides a format for assets and metadata that satisfies the above desiderata, facilitates reproducibility, open access, and sharing of materials through online platforms like GitHub and Open Science Framework. We discuss a stack of R resources that help users create reproducible collections of research assets, from experiments to manuscripts, in the RStudio interface. We created an R package, vertical, to help researchers incorporate these tools into their workflows, and discuss its functionality at length in an online supplement. Together, these tools may increase the reproducibility and openness of psychological science.Recognizing musical notation is an important skill to a full participation of Western classical music, but remains a largely under-researched topic in the psychology of music. One plausible reason of such omission is that, in the past, the research field has heavily relied on self-report of music reading ability, which was subjective and highly variable. This paper presents a reliable and valid tool for objectively measuring individual abilities in visual recognition of musical notation. The visual fluency task measures how fast one can accurately recognize a sequence of musical notation at a desired accuracy level using the adaptive psychometric method QUEST. We checked the reliability of this task in over 200 participants in terms of Guttman's λ-2 and Cronbach's alpha. Also, we evaluated the construct validity of this task by considering the convergent validity of this task with multiple external real-world measures of one's musical training background, with numerous experimental measures of visual tendencies of musical notation recognition and with sight-reading performance. Overall, the visual fluency task achieved satisfactory reliability and validity for measuring abilities in recognizing musical notation. This opens the door for characterizing the cognitive mechanisms, development, and individual differences in musical notation recognition, for understanding music learning and music psychology and for understanding of visual perceptual expertise in general.Recordings captured by wearable microphones are a standard method for investigating young children's language environments. A key measure to quantify from such data is the amount of speech present in children's home environments. To this end, the LENA recorder and software-a popular system for measuring linguistic input-estimates the number of adult words that children may hear over the course of a recording. However, word count estimation is challenging to do in a language- independent manner; the relationship between observable acoustic patterns and language-specific lexical entities is far from uniform across human languages. In this paper, we ask whether some alternative linguistic units, namely phone(me)s or syllables, could be measured instead of, or in parallel with, words in order to achieve improved cross-linguistic applicability and comparability of an automated system for measuring child language input. CDK inhibitor We discuss the advantages and disadvantages of measuring different units from theoretical and technical points of view. We also investigate the practical applicability of measuring such units using a novel system called Automatic LInguistic unit Count Estimator (ALICE) together with audio from seven child-centered daylong audio corpora from diverse cultural and linguistic environments. We show that language-independent measurement of phoneme counts is somewhat more accurate than syllables or words, but all three are highly correlated with human annotations on the same data. We share an open-source implementation of ALICE for use by the language research community, enabling automatic phoneme, syllable, and word count estimation from child-centered audio recordings.Chemoresistance is a complex phenomenon responsible for failure in response to chemotherapy agents and more than 90% of deaths in cancer patients. MicroRNAs (miRNAs), as a subgroup of non-coding RNAs with lengths between 21 and 25 nucleotides, are involved in various cancer processes like chemoresistance via interacting with their target mRNAs and suppressing their expression. Autophagy is a greatly conserved procedure involving the lysosomal degradation of cytoplasmic contents and organelles to deal with environmental stresses like hypoxia and starvation. Autophagy contributes to response to chemotherapy agents autophagy can act as a protective mechanism for mediating the resistance in response to chemotherapy or can induce autophagic cell death and mediate the sensitivity to chemotherapy. On the other hand, one of the processes targeted by microRNAs in the regulation of chemoresistance is autophagy. Hence, we studied the literatures on chemoresistance mechanisms, the miRNAs' role in cancer, and the miRNAs' role in chemoresistance by modulating autophagy. Graphical Abstract.Blastocystis sp. is a common enteric parasite of humans and animals associated with inadequate sanitation and poor personal hygiene. Over the years, the Malaysian thriving economy has been facilitated largely by migrant workers from developing countries, and there is concern that diseases endemic to their countries may be imported. Therefore, this study aimed to determine the current status of Blastocystis infection as well as subtypes (STs) from fecal samples among migrant workers in Selangor and Kuala Lumpur, Malaysia. Overall, almost a third of the study cohort (30.9%; n = 68/220) screened were infected with Blastocystis sp. predominantly with ST3 (54.5%; n = 12), followed by ST1 (36.4%; n = 8) and ST2 (9.1%; n = 2). Infection levels was almost similar among the different sectors; manufacturing (32.8%), domestic service (32.3%), and food service (27.3%) with common symptoms for infection included stomach and abdominal pain or discomfort and diarrhea (48.5%; n = 33). None of the socio-demographic risk factors evaluated were significant.
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