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Lymphomatoid granulomatosis is a very rare B cell lymphoproliferative disease associated with Epstein-Barr virus infection. It is related to states of immunosuppression and affects the lung in more than 90% of cases, forcing the clinician to establish a differential diagnosis with other diseases such as infections, Wegener's granulomatosis, lymphoma, or lung metastases. There is no standard treatment for this disease. In this paper, we describe a rare case of a patient with grade 3 lymphomatoid granulomatosis with newly diagnosed HIV infection who started antiretroviral treatment with a gradual improvement of the lesions.
Research has shown that yoga may be an effective adjunctive treatment for persistent depression, the benefits of which may accumulate over time. The objectives of this study were to evaluate the following in a sample of persistently depressed individuals whether yoga increases mindfulness and whether yoga attenuates rumination. Rumination and mindfulness both represent attentional processes relevant for onset and maintenance of depressive episodes.
One-hundred-ten individuals who were persistently depressed despite ongoing use of pharmacological treatment were recruited into an RCT comparing yoga with a health education class. Mindfulness and rumination were assessed at baseline and across 3 time points during the ten-week intervention.
Findings demonstrate that, compared to health education, yoga was associated with higher mean levels of the observe facet of mindfulness relative to the control group during the intervention period (
=.004,
=0.38), and that yoga was associated with a faster rate of c factors such as age.
Although much research examining youth psychopathology from an ecological family systems theoretical framework has highlighted negative or pathological parental characteristics, it is important to identify and explore beneficial parent characteristics, such as mindful attention and awareness, that may be related to youth mental health. Dispositional mindfulness has been related, in cross-sectional research, to higher levels of mindful parenting, which impacts positive and negative parenting and, in turn, offspring internalizing and externalizing symptoms. The current study expands this work by examining associations among caregiver dispositional mindful attention, mindful parenting, parenting behaviors, and youth psychopathology in a short-term longitudinal model and by testing potential moderators.
A sample of 564 parents (60% mothers) of children between the ages of 3 and 17 reported on their dispositional mindful attention, mindful parenting, positive and negative parenting practices, and their youth'stal health.
The goal of the present study was to determine whether baseline mindful eating, general mindful awareness, or acceptance was most strongly associated with short- and long-term weight loss in a lifestyle modification program.
Data were from 178 participants (baseline BMI=40.9±5.9 kg/m
, age=44.2±11.2 years; 87.6% female; 71.3% black) who enrolled in a two-phase trial. All participants attended an initial 14-week lifestyle modification program that included a meal replacement diet. Participants who had lost ≥5% of initial weight (
=137) were then randomized to 52 weeks of lifestyle modification with lorcaserin or placebo. Linear mixed models examined whether mindful eating (Mindful Eating Questionnaire) and general mindful awareness and acceptance (Philadelphia Mindfulness Scale) predicted short-term weight loss at week 14 in the full sample and long-term weight loss at the end of the trial in the subsample of randomized participants.
In the full sample, higher baseline acceptance predicted greater short-term weight losses (
=.004). At week 14, individuals low in acceptance (-1
) lost an average of 8.7 kg (
=0.6) compared to 11.2 kg (
=0.6) among those high in acceptance (+1
). In the subsample of participants who successfully lost weight in phase 1, the independent effect of acceptance on total losses at the end of the trial did not reach statistical significance (
=.058). Neither mindful eating nor general mindful awareness independently predicted weight loss at either time point.
Acceptance was a stronger predictor than either general or eating-specific awareness of weight loss with lifestyle modification.
Acceptance was a stronger predictor than either general or eating-specific awareness of weight loss with lifestyle modification.
The need for remote delivery of mental health interventions including instruction in meditation has become paramount in the wake of the current global pandemic. However, the support one may usually feel within the physical presence of an instructor may be weakened when interventions are delivered remotely, potentially impacting one's meditative experiences. Use of head-mounted displays (HMD) to display video-recorded instruction may increase one's sense of psychological presence with the instructor as compared to presentation via regular flatscreen (e.g., laptop) monitor. Darapladib mouse This research therefore evaluated a didactic, trauma-informed care approach to instruction in mindfulness meditation by comparing meditative responses to an instructor-guided meditation when delivered face-to-face vs. by pre-recorded 360° videos viewed either on a standard flatscreen monitor (2D format) or via HMD (i.e., virtual reality [VR] headset; 3D format).
Young adults (
= 82) were recruited from a university introductory course umatic stress symptoms were risk factors for experiencing distress while meditating in either (VR and non-VR) instructional format. Of those who reported a preference for one format, approximately half preferred the VR format and approximately half preferred the IV format.
Recorded 360° video instruction in meditation viewed with a HMD (i.e., VR/3D format) appears to offer some experiential advantage over instructions given in 2D format and may offer a safe-and for some even preferred-alternative to teaching meditation face-to-face.
The online version contains supplementary material available at 10.1007/s12671-021-01612-w.
The online version contains supplementary material available at 10.1007/s12671-021-01612-w.
Website: https://www.selleckchem.com/products/darapladib-sb-480848.html
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