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Any Genome-Wide Profiling regarding Glioma People with the IDH1 Mutation With all the Catalogue regarding Somatic Variations in Cancer Database.
The present study intended to examine the direct effects of perceived spousal support and postpartum depression on postpartum maternal bonding. Furthermore, it also explored the mediating role of postpartum depression between perceived spousal support and postpartum maternal bonding.

This study was based on a cross-sectional survey research design. A purposive sample of 170 women who were already diagnosed by the doctor/psychiatrist as suffering from postpartum depression was recruited from different hospitals of Gujrat district. Urdu translated versions of The Marital Empathy Scale, Postpartum Bonding Questionnaire, and the Edinburgh Postnatal Depression Scale were used to measure the focal constructs of the study.

IBM Amos was used to test the proposed model of the present study. Path analysis revealed that perceived spousal support had negative significant direct effects on postpartum depression and postpartum maternal bonding. Postpartum depression had significant positive direct effect on postpartum maternal bonding. Finally, the significant indirect effect of perceived spousal support through postpartum depression on postpartum maternal bonding was negative.

The mediation found in the present study suggested that perceived spousal support reduced the postpartum depression, which in turn, lowered the chances of dysfunctional postpartum maternal bonding with the baby. Implications of the study along with the recommendations for future studies have been reflected upon.
The mediation found in the present study suggested that perceived spousal support reduced the postpartum depression, which in turn, lowered the chances of dysfunctional postpartum maternal bonding with the baby. Implications of the study along with the recommendations for future studies have been reflected upon.
Acne vulgaris has been a common clinical condition. Due to. high prevalence and unclear etio-pathogenesis of acne vulgaris, large number of treatment options have been available across the globe. Limited work has been done to explore the options which may manage or prevent these adverse effects and improve the adherence to the prescribed medications. We therefore conducted this trial to look for effectiveness of oral omega 3 in reducing mucocutaneous side effects of oral isotretinoin in patients with acne vulgaris.

To look for effectiveness of oral omega 3 in reducing mucocutaneous side effects of oral isotretinoin in patients with acne vulgaris. It was a randomized control trial conducted at Department of Dermatology Pak Emirates Military Hospital Rawalpindi. Ten months, June 2019 to May 2020.

A total of 60 patients of acne vulgaris put on oral isotretinoin by consultant dermatologist were included in the study. selleck inhibitor Patients were randomized into groups by lottery method. Group A received the placebo along der to prevent or manage cheilitis, xerosis or dry lips.
Mucocutaneous side effects were a very common finding among patients of acne vulgaris managed with isotretinoin. Cheilitis was the most reported mucocutaneous side effects among the target population. This RCT demonstrated that omega 3 was superior to placebo in order to prevent or manage cheilitis, xerosis or dry lips.
Recently the Coronavirus pandemic presented with different manifestations in different parts of the world, both on clinical examinations and on imaging. CT Scanning (CT Scan) chest is used for detailed evaluation of the different characteristic patterns determining the depth of disease. The study is aimed to assess the variations in spectrum of Covid-19 CT findings and relating severity (CT Severity Score) with the Clinical Symptoms in Bahawal Victoria Hospital, Bahawalpur.

In this cross-sectional study, patients referred to radiology department from outdoor for COVID screening were included from 1st May to 30th June 2020. Mean age range of patients was calculated, while presenting complaints and co-morbidities were tabulated in frequencies and percentages after analysis. Severity of symptoms and CT findings were correlated with biochemical and haematological tests.

Patients' age range from 25 to 85 years with 62% males and 38% females. Statistically no significant difference was observed in CTSS on gensing 40-point CTSS scoring on Imaging could provide a timely and objective approach towards identifying patients requiring intensive care and hospitalisation.
Combination of DAAs, Sofosbuvir and Ribavirin has been known as an effective treatment for HCV genotype 3. The aim of our study is to assess the efficacy of Sofosbuvir and Ribavirin in relapsed HCV genotype 3 patients.

A cross-sectional retrospective analysis of hospital records between January 2015 and December 2016. Data was taken of only those patients who were followed for one year. A total of 193 cases were included in this study who were HCV genotype 3 relapsers and out of these 28 patients failed to be followed. Data was entered and analysed in IBM SPSS software package 23.

Out of the total 193 cases, 74.1% of cases achieved RVR at 4 weeks of therapy. ETR was achieved by 91.2% cases, while 8.8% of cases were non-responders. There was statistical significance in gender achieving ETR with a p-value of .008. 84.5% of cases achieved SVR-12. Statistical significance was noted between haemoglobin levels at presentation and 4 weeks follow-up with a p-value <0.005, and also between 4 weeks and 12 weeks follow-up with a p-value <0.005. Statistical significance was also found between age and PCR at 4 weeks (p-value of .002), age and PCR at 24 weeks (p-value of .051) and between ALT levels and PCR at 4, 12 and 24 weeks follow up (p-value <0.005). At 1-year follow-up, 79.3% of cases achieved a negative PCR, 28 patients failed to be followed, 6.2% of cases had a positive PCR. 5.5% of cases of the total 163 SVR cases had a relapse at 1 year.

HCV genotype 3 patients can benefit from Sofosbuvir and Ribavirin. With the SVR of more than 80%, this combination is cost-effective and safe. Treatment duration should be dependent on RVR and viral load at 4 weeks follow-up.
HCV genotype 3 patients can benefit from Sofosbuvir and Ribavirin. With the SVR of more than 80%, this combination is cost-effective and safe. Treatment duration should be dependent on RVR and viral load at 4 weeks follow-up.
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