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Proteomic Portraits Expose Evolutionarily Maintained along with Divergent Replies in order to Spinal Cord Injury.
The domination of Brahmin and the upper caste scientists have given a Brahmanical identity to science in India. They have been perceived to be the natural inheritors of scientific practice, an assertion reaffirmed by scientists and researchers during my fieldwork in Bangalore, India. Furthermore, merit and passion for doing science was reinscribed and calibrated to denote the alleged castelessness and objectivity of science, obfuscating the deep hierarchies of caste in the practice of science in India. By using ethnographic methods, the article attempts to demonstrate how Indian scientists constructed their identities as casteless beings. The article calls for a public understanding of caste in Indian science, and suggests that public engagement has the potential to democratise the nature of science by addressing the question of exclusion and discrimination in Indian scientific institutions and universities.Gaining a complete understanding of transmission risk factors will assist in efforts to reduce new HIV infections, especially within the disproportionally affected population of men who have sex with men (MSM). We recently reported that the fecal microbiota of MSM elevates immune activation in gnotobiotic mice and enhances HIV infection in vitro over that of fecal microbiota from men who have sex with women. We also demonstrated elevation of the gut homing marker CD103 (integrin αE) on CD4+ T cells by MSM-microbiota. Here we provide additional evidence that the gut microbiota is a risk factor for HIV transmission in MSM by showing elevated frequencies of the HIV co-receptor CCR5 on CD4+ T cells in human rectosigmoid colon biopsies. We discuss our interest in specific MSM-associated bacteria and propose the influx of CD103+ and CCR5+ CD4+ T cells into the colon as a potential link between the MSM microbiota and HIV transmission.Developmental dyslexia is defined as a specific reading disorder but is also thought to be underpinned by a deficit in motor skills that may well affect handwriting performance. However, the results of studies addressing this issue are not consistent. The present study was, therefore, designed to better understand the functioning of handwriting in children with dyslexia, by conducting an analysis of the legibility and fluency of handwritten letters, supplemented by an assessment of motor skills. The performances of 15 children with dyslexia (Mage = 11.4 years) were compared with those of two groups of typically developing children, one matched for chronological age, the other for orthographic level (Mage = 8.7 years) on two handwriting measures (production of the letters of the alphabet and the child's first name and surname). Results revealed a delay in motor skills, as well as in letter legibility, letter production duration, and the number of short pauses (i.e., lasting between 20 and 199 ms) made during letter production, in the children with dyslexia, with strong negative correlations between motor skills and the number of short pauses. Results are discussed in the context of handwriting control development in children, and perspectives are set out for practitioners.Background The IAEA/WHO postal dose audit programme has been operating since 1969 with the aim of improving the accuracy and consistency of dosimetry in radiotherapy in low-income and middle-income countries world-wide. This study summarises the 50 years' experience of audits and explores the quality of reference dosimetry in participating radiotherapy centres throughout the years.Material and methods During the IAEA/WHO postal audits the dose determined from the mailed dosimeter is compared with that stated by the participant. Agreement to within ±5% is regarded acceptable whilst deviations outside ±5% limits trigger follow-up actions. Of particular interest in this study was the dependence of clinical dosimetry quality on factors related to the centre infrastructure and expertise in dosimetry of its staff.Results The IAEA/WHO dose audit programme noted great increase in the overall percentage of acceptable results from about 50% in its early years to 99% at present, although there is some variability of results amongst participating countries. Whereas results for younger radiotherapy machines show the agreement rate between the measured and the stated doses well above 90%, for those over 20 years old the rate dropped to less then 80%. Linac dosimetry was always better than 60Co dosimetry and multi-machine centres generally performed better than single machine centres equipped with cobalt alone. Second and subsequent participation in audits showed higher quality dosimetry than the first participation. The implementation of modern dosimetry protocols resulted in more accurate dosimetry than the use of the older protocols.Conclusions Over the 50 years that the IAEA has accumulated dosimetry audit data, practices in radiotherapy centres have significantly improved. Phloridzin Higher quality dosimetry confirmed in audits is generally associated with better infrastructure and adequate dosimetry expertise of medical physicists in participating centres.Previous research in the Middle East and North Africa has revealed justifying attitudes toward wife beating among adults, but little is known about adolescent attitudes and its predictors. Therefore, the purpose of the present study was to examine theoretically relevant predictors of supportive attitudes toward wife beating among adolescents in Jordan. Due to limited evidence on the role of gender, potential differences between girls and boys were explored. A total of 856 students (455 female) from 14 secondary schools in Amman, the capital city of Jordan, participated in the cross-sectional study which was conducted during normal school hours. Religiosity, beliefs regarding control of female sexuality, moral neutralization of aggression, and parental harsh discipline were assessed to predict attitudes toward wife beating, controlling for sociodemographic variables. Acceptance rates of wife beating ranged between 6.1% and 50.5%. Hierarchical regression analysis showed that beliefs supporting control of female sexuality, moral neutralization of aggression, and paternal harsh discipline predicted supportive attitudes toward wife beating, but religiosity and maternal harsh discipline did not.
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