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Forty-four patients (13.2%) were rejected for rhinoplasty since consensus was not achieved during morphing. From 290 accepted patients, 178 underwent their operation (53.3%), 74 patients (22.1%) postponed their rhinoplasty, and 38 (11.4%) cancelled their surgery. Fifty-seven percent of rejected patients and 42% of the static group were not satisfied with the proposed results of morphing, in contrast with 16% of the operated group. Sixty-four percent of rejected patients, and 47% of the static group were not reassured after morphing, compared with 26% of the operated group. Presence or absence of consensus during morphing can guide the surgeon regarding a given patients' suitability for surgery. Patient satisfaction and reassurance with the morphed images can be a good predictor of patients who will proceed to surgery, calling attention to the value of morphing as a selection tool for surgeons and patients alike. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.In this systematic review we aim to (1) describe the anatomy and function of the soft tissue triangle, (2) identify the existing rhinoplasty literature that discusses the role of the soft tissue triangle, (3) provide a summary of the outcome measures for soft tissue triangle techniques in rhinoplasty, and (4) demonstrate the need for further research reviewing soft tissue triangle techniques in rhinoplasty. A systematic literature review was conducted from 2002 to 2019 utilizing MEDLINE/PubMed, Embase, Ovid, and Cochrane databases with the keywords, "rhinoplasty" and "soft tissue triangle" or "facet" to identify articles that describe the anatomical significance, clinical applicability, and rhinoplasty outcomes involving the soft tissue triangle. A total of 26 studies were identified as appropriate for inclusion. The vast majority describe the relationship of structure and function of the soft tissue triangle with particular focus on notching and retraction. The soft tissue triangle is an important area of the nose often neglected in rhinoplasty. This area is a common source of patient dissatisfaction and the need for revision rhinoplasty. Due to this fact, a formal evaluation of the role of the soft tissue triangle in nasal airway patency is needed. Specific validated outcome measures such as the NOSE (Nasal Obstruction and Septoplasty Effectiveness) score or the SCHNOS (Standardized Cosmesis and Health Nasal Outcomes Survey) should be employed in the evaluation of surgical intervention to the soft tissue triangle. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Background Randomized trials have shown that initiating breast cancer screening between ages 50 and 69 years and continuing it for 10 years decreases breast cancer mortality. However, no trials have studied whether or when women can safely stop screening mammography. An estimated 52% of women aged 75 years or older undergo screening mammography in the United States. Objective To estimate the effect of breast cancer screening on breast cancer mortality in Medicare beneficiaries aged 70 to 84 years. Design Large-scale, population-based, observational study of 2 screening strategies continuing annual mammography, and stopping screening. Setting U.S. Medicare program, 2000 to 2008. Participants 1 058 013 beneficiaries aged 70 to 84 years who had a life expectancy of at least 10 years, had no previous breast cancer diagnosis, and underwent screening mammography. Measurements Eight-year breast cancer mortality, incidence, and treatments, plus the positive predictive value of screening mammography by age group. Results In women aged 70 to 74 years, the estimated difference in 8-year risk for breast cancer death between continuing and stopping screening was -1.0 (95% CI, -2.3 to 0.1) death per 1000 women (hazard ratio, 0.78 [CI, 0.63 to 0.95]) (a negative risk difference favors continuing). In those aged 75 to 84 years, the corresponding risk difference was 0.07 (CI, -0.93 to 1.3) death per 1000 women (hazard ratio, 1.00 [CI, 0.83 to 1.19]). Limitations The available Medicare data permit only 8 years of follow-up after screening. As with any study using observational data, the estimates could be affected by residual confounding. Conclusion Continuing annual breast cancer screening past age 75 years did not result in substantial reductions in 8-year breast cancer mortality compared with stopping screening. Primary Funding Source National Institutes of Health.Background Sugar-sweetened beverage (SSB) consumption is linked to adverse health outcomes. selleck inhibitor Objective To evaluate the impact of the 2017 Cook County, Illinois, Sweetened Beverage Tax (SBT) on the volume of taxed and untaxed beverages sold in Cook County and its 2-mile border area. Design Pre-post intervention-comparison site difference-in-differences study. Setting Cook County, Illinois, and St. Louis City and County, Missouri, 2016 to 2017. Participants Universal product code-level store scanner data from supermarkets and grocery, convenience, drug, mass merchandise, and dollar stores. Measurements Beverage volume sold of taxed and untaxed beverages, across product categories and sizes. Results Volume sold of taxed beverages decreased by 27% (ratio of incidence rate ratios [RIRR], 0.73 [95% CI, 0.70 to 0.75]) on average in Cook County relative to St. Louis during the 4 months that the SBT was in effect (compared with the same 4-month pretax period), with a net decrease of 21% after increases in volume sold irce Bloomberg Philanthropies.Background Chronic obstructive pulmonary disease (COPD) is characterized by frequent exacerbations. Purpose To evaluate the comparative effectiveness and adverse events (AEs) of pharmacologic interventions for adults with exacerbation of COPD. Data Sources English-language searches of several bibliographic sources from database inception to 2 January 2019. Study Selection 68 randomized controlled trials that enrolled adults with exacerbation of COPD treated in out- or inpatient settings other than intensive care and compared pharmacologic therapies with placebo, "usual care," or other pharmacologic interventions. Data Extraction Two reviewers independently extracted data and rated study quality and strength of evidence (SOE). Data Synthesis Compared with placebo or management without antibiotics, antibiotics given for 3 to 14 days were associated with increased exacerbation resolution at the end of the intervention (odds ratio [OR], 2.03 [95% CI, 1.47 to 2.80]; moderate SOE) and less treatment failure at the end of the intervention (OR, 0.
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