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The entomopathogenic fungus (EPF) Metarhizium brunneum occupies the same ecological niche as entomopathogenic nematodes (EPN), with both competing for insects as a food source in the rhizosphere. selleck products Interactions between these biocontrol agents can be antagonistic or synergistic. To better understand these interactions, this study focussed on investigating the effect of M. brunneum volatile organic compounds (VOCs), 1-octen-3-ol and 3-octanone, on EPN survival and behaviour. These VOCs proved to be highly toxic to the infective juveniles (IJs) of the EPN Steinernema carpocapsae, Steinernema feltiae and Heterorhabditis bacteriophora with mortality being dose dependent. Chemotaxis studies of H. bacteriophora IJs in Pluronic F127 gel revealed significant preference for the VOCs compared with controls for all tested concentrations. The VOCs also impacted on the test insects in a dose-dependent manner with 3-octanone being more toxic to Galleria mellonella, Cydia splendana and Curculio elephas larvae than 1-octen-3-ol. Mortality of C. splendana and G. mellonella larvae was significantly higher when exposed to relatively high doses (>25%) of 3-octanone. Lower doses of 3-octanone and 1-octen-3-ol immobilised test insects, which recovered after exposure to fresh air for 2 hrs. In depth studies on H. bacteriophora showed that exposure of IJs to > 10% concentration of 3-octanone or 1-octen-3-ol negatively affected infectivity whereas exposure to lower doses (0.1%, 0.01%) had no effect. The VOCs affected IJs, reducing penetration efficacy and the number of generations inside G. mellonella but they failed to inhibit the bacterial symbiont, Photorhabdus kayaii. The ecological significance of VOCs and how they could influence EPF-EPN insect interactions is discussed.The COVID-19 health crisis has reached pandemic scale spreading globally. The present study examines the COVID-19 pandemic's impact on psychological and physical health-related quality of life (HRQOL) among university students in Turkey. A cross-sectional survey design was used for data collection. From May 11th to May 15th 2020, the study utilized snowball sampling techniques to gather data through an online survey. The pandemic's psychological effects on participants were measured by the Impact of Event Scale-Revised. Depression, Anxiety and Stress Scale-21 and the 12-Item Short Form Health Survey assess related HRQOL were used to make mental health assessments. 1120 university students were contacted to complete the survey. Of these, a total of 1095 completed the survey, translating to a participation rate of 97.7%. Overall, 64.6%, 48.6% and 45.2%, and 34.5% of all participants self-reported symptomatic signs of depression, anxiety, stress and post-traumatic stress disorder (PTSD), respectively. Female gender and poor family relationships were identified as risk factors for probably PTSD, and symptoms of depression, anxiety, and stress as well. The mean scores of Physical Component Summary (PCS-12) and Mental Component Summary (MCS-12) were 66.99 ± 2.14 and 40.76 ± 2.31, respectively. Students suspected of a history with PTSD had considerably lower total scores for PCS-12 and MCS-12, when cross checked for similarity to those without such a history. The findings of this research suggest that evidence of PTSD, depression, anxiety, and stress is commonly apparent among university students during the period of the COVID-19 crisis. Prevention and intervention approaches to attenuate the psychosocial impact should be an integral component of crisis response during pandemic conditions.Single crystal structures in a series of 7-bromo-, 8-bromo-, and 7,8-dibromo-3-tert-butylpyrazolo[5,1-c][1,2,4]triazin-4(1H)-ones have been investigated by X-ray diffraction. Novel 7-bromo- and 7,8-dibromo-3-tert-butylpyrazolo[5,1-c][1,2,4]triazines were synthesized by reduction of triazine carbonyl with dehydrative aromatization in acidic media, and their XRD structural features were compared with that of the 4-oxo analogs. The lengths and bond angles and the packing of molecules in crystals have been considered. Non-valence interactions for some of the studied compounds were observed. Correlations between the presence of bromine atoms at different positions and structural features are determined.
The online version contains supplementary material available at 10.1007/s11224-021-01768-0.
The online version contains supplementary material available at 10.1007/s11224-021-01768-0.The centrality of building care economies as a necessary step towards gender justice requires a reassessment of global economic governance and state-centred multilateralism. Globalized structures of power can no longer be seen solely as matters of political borders of nation-states, which is the traditional remit of foreign policy. Rather than geography, it is negotiations over the boundaries of power that must be interrogated for the possibility of redrawing borders and boundaries as these are expressed in social relations where care functions are performed. Five spheres of engagement are identified and discussed. A short note on limitarianism raises a question about its value in a care economy and how ethics of care links to it.Both electrospinning apparatus and their commercial products are extending their applications in a wide variety of fields. However, very limited reports can be found about how to implement an energy-saving process and in turn to reduce the production cost. In this paper, a brand-new type of coaxial spinneret with a solid core and its electrospinning methods are developed. A novel sort of medicated Eudragit/lipid hybrid nanofibers are generated for providing a colon-targeted sustained release of aspirin. A series of characterizations demonstrates that the as-prepared hybrid nanofibers have a fine linear morphology with the aspirin/lipid separated from the matrix Eudragit to form many tiny islands. In vitro dissolution tests exhibit that the hybrid nanofibers are able to effectively prevent the release of aspirin under an acid condition (8.7%±3.4% for the first two hours), whereas prolong the drug release time period under a neutral condition(99.7±4.2% at the seventh hour). The energy-saving mechanism is discussed in detail.
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