Notes

Modern kind of 3D-printed nasopharyngeal kid scraping regarding COVID-19 recognition.
The removal of phenolic compounds, a group of environmental pollution even at low concentrations, by the adsorption process has attracted considerable attention around the world. Still, the choice of an absorbent has proved to be a challenge. As a result, for the first time, functionalized graphene (FG)/sericin nanocomposites to be applied as an adsorbent to remove phenolic compounds from aquatic systems. Sericin, the by-product of the silk process, was naturally benign and economically available matrices, which used to preparation of FG/sericin nanocomposites. The FG was prepared with the reaction between graphite and maleimide, then sericin attached to FG sheets by the amidation reaction. Because of the abundance of chemically active functional groups on the surface of these FG/sericin nanocomposites have been found to be excellent for decontamination of water for phenolic compound removal applications.The present work is conducted in the industrial district south of greater Cairo (ElTabbin area). Some heavy metals like Mn, Co, Ni, Cu, Zn, Pb, Cr, Ba, Cd, Mo were determined in polluted soils during May, 2018. KU-55933 order At the study area, results displayed that average heavy metals concentrations differ considerably. They are decreased from Mn to Cd (Mn > Ba > Zn > Cr > Ni > Co > Pb > Cu > Mo > Cd). The average ranges as follows Mn (255.8-31448.2 ppm); Ba (145.2-17545.6 ppm); Zn (53.3-1589.9 ppm); Cr (26.7-311.3 ppm); Ni (29.7-114.1 ppm); Co (13.2-39.8 ppm); Pb (5.7-77.4 ppm); Cu (7.6-35.2 ppm); Mo (0.1-15.9 ppm) and Cd (0-1.5 ppm), respectively. ElTabbin area has heavy manufacturing activity at Egypt. ElTabbin area was chosen as a model for that contamination. Electrical characteristics of some specimens from El- Tebbin area, Egypt, were taken and measured electrically at frequency range (10-3 to 100 kHz). Major and heavy elements were measured at specimens. Specimens were classified to three categories according to electrical properties. The changes were the consequence of change in minor and major mineral composition in the specimens. Electrical properties were able to recognize different specimens according to different levels of contaminants in the specimens. Texture, tortuosity and minor elements of heavy elements are the controlling factors that control electrical properties at specimens. High values concentration of Mn, Ni, and Zn heavy elements increases conductivity while the high concentration of Pb and Cu heavy elements decreases the conductivity. The mixing up of these different minor and major minerals and elements at specimen may lead to the change of conductivity values. The main controlling factors of the major elements are the Fe2O3 and SiO2, while the main controlling factors of the minor elements are the Mn and Pb. Our main objective is to study mixing up of the different minor and major minerals and elements on electrical properties of rocks.β-cell dedifferentiation has been accounted as one of the major mechanisms for β-cell failure; thus, is a cause to diabetes. We study direct impacts of liraglutide treatment on ex vivo human dedifferentiated islets, and its effects on genes important in endocrine function, progenitor states, and epithelial mesenchymal transition (EMT). Human islets from non-diabetic donors, were purified and incubated until day 1 and day 4, and were determined insulin contents, numbers of insulin (INS+) and glucagon (GCG+) cells. The islets from day 3 to day 7 were treated with diabetic drugs, the long acting GLP-1 receptor agonist, liraglutide. As observed in pancreatic islets of type 2 diabetic patients, ex vivo dedifferentiated islets showed more than 50% reduced insulin contents while number of glucagon increased from 10% to about 20%. β-cell specific genes PDX1, MAFA, as well as β-cell functional markers GLUT1 and SUR1, were significantly depleted more than 40%. Notably, we found increased levels of glucagon regulator, ARX and pre-glucagon transcripts, and remarkably upregulated progenitor expressions NEUROG3 and ALDH1A identified as β-cell dysfunction markers in diabetic models. Hyperglucagonemia was often observed in type 2 patients that could lead to over production of gluconeogenesis by the liver. Liraglutide treatments resulted in decreased number of GCG+ cells, increased numbers of GLP-1 positive cells but did not alter elevated levels of EMT marker genes ACTA2, CDH-2, SNAIL2, and VIM. These effects of liraglutide were blunted when FOXO1 transcripts were depleted. This work illustrates that ex vivo human isolated islets can be used as a tool to study different aspects of β-cell dedifferentiation. Our novel finding suggests a role of GLP-1 pathway in beta-cell maintenance in FOXO1-dependent manner. Importantly, dedifferentiated islets ex vivo is a useful model that can be utilized to verify the actions of potential drugs to diabetic β-cell failure.
A range of phototherapy devices are commercially available. The American Academy of Pediatrics (2004) recommends routine intensity measurement of phototherapy devices to ensure that babies affected by hyperbilirubinemia receive effective phototherapy.

The aims of this study were to calculate the irradiance decay velocity of phototherapy devices used in a tertiary care hospital to evaluate whether current maintenance procedures for phototherapy devices are effective, and to contribute to the improvement of a standardized maintenance procedure in daily practice, thus helping to ensure that all babies affected by hyperbilirubinemia receive prompt treatment.

This research represents a prospective observational study conducted at Dr. Soetomo Academic Teaching Hospital in Surabaya, Indonesia from February 2019-July 2019. The intensities of 11 phototherapy devices were measured at specific times using a Bili Blanket Meter II. We calculated the Δ irradiance differences in μW/cm
/nm and calculated them as veloc intensity measurements, regardless of manufacturer recommendations, to avoid ineffective phototherapy resulting from intensities lower than the required therapeutic levels.Eragrostiella brachyphylla is an angiosperm desiccation-tolerant resurrection plant, which can survive during desiccation in the air-dry state and recover completely on availability of water. The present study was conducted to understand the vegetative desiccation tolerance of Eragrostiella brachyphylla by evaluating its ability to recover the physiological, biochemical and morphological functions post desiccation. In order to understand the responses of Eragrostiella brachyphylla to desiccation and subsequent rehydration experiments were conducted in the hydrated state (HS), desiccated state (DS) and rehydrated state (RS). Scanning electron microscopy revealed significant changes between the three stages in the internal ultra-structures of leaves and stems. Compared to the other states, photosynthetic parameters such as chlorophyll a, chlorophyll b, total chlorophylland total carotenoid contents decreased significantly in the desiccated state. Superoxide radical (O2•-) content also increased, resulting in an oxidative burst during desiccation.
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