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It has been possible to distinguish preferential phenotypes depending on the etiology of the dementia. CONCLUSION The results confirm the interest of the phenomenological approach to distinguish the etiology of the PS among confirmed dementias. Prospective longitudinal studies must examine the early discriminant characteristics of PS in order to enable a better prognostic prediction of the nosographic frame thereby established.False memories refer to falsely remembering something that did not happen or that happened differently. The effects of age on episodic memory underlie both the decline in real memories and the increase in false memories. But, what is the richness and what is the feeling of reality of false memories in the elderly? This mini-review on false memory in young and older adults presents the results from the literature using one of the most used paradigms in the laboratory to study false memories - the Deese-Roediger-McDermott paradigm. This paradigm generally consists in the presentation of semantically associated items-lists (words or images) related to a non-presented critical lure (e.g., bed, rest, awake …, the critical lure is sleep). During free recall or recognition tests, the participants regularly produce false memories (intrusions or false recognitions of the critical lures), increasingly with aging. We specifically ask the question of the richness of the false memory trace in young and older adults in terms of contextual associations (What-Where-When-Details binding) and phenomenological characteristics (remembering, knowing, guessing). We propose to examine this issue using a naturalistic episodic memory task via navigation in a virtual environment enriched with series of associated elements (e.g., vegetables stand) linked to non-presented critical lures (e.g., carrots). Based on preliminary results, we propose an integrative model of memory trace which can explain the differences observed between young and old people on the richness of their false memories.Screening and management of frail elderly patients is essential in general practice. OBJECTIVE This study aims to describe and evaluate the knowledge about frailty, its screening tests and management in a population of general practice interns. METHOD A prospective, descriptive and mono-centric study using an online survey was conducted. The 2018's promotion of general practice interns in Rouen's University participated. Evaluation of the general knowledge (e.g diagnostic criteria) and specific knowledge (e.g ranking different conditions such as undernourishment leading to asthenia) and management algorithm (e.g to address the patient for geriatric evaluation) Results 90 questionnaires were analyzed. Ten interns (11%) stated to know at least one screening test or to know a set of 4 major frailty criteria. Thirty four interns knew at least 4 frailty criteria (major or minor) and 46 interns had partial knowledge. Fried's phenotype was the most known. Seventy-five interns (83%) stated to know the frailty syndrome. However, 88% of the interns had little knowledge about its pathophysiology. Concerning frailty management, 78% (70 interns) stated to know how to screen frailty and prescribe first line treatments. Thirty-one among them knew how to reassess initial treatment if failure. In 59 interns (65%), identifying frailty would have led to a geriatric consultation. Seventy-nine interns (87%) were favorable to go through further training on frailty. CONCLUSION These general practice interns were able to identify frailty criterion but, in contrast, global understanding of the syndrome was missing. Lapatinib mouse Further training about this topic seems to be necessary.Therapeutic patient education (TPE) allows elderly as well as young adults to evaluate patient's self-care and adaptation skills to their own clinical condition. Falling is a symptom present in various chronic diseases, which leads to loss of autonomy, fear of recidivism and frequent admissions into institutions. Study objective was to evaluate at 3 and 6 months the impact of TPE on fall recurrence, perceived quality of life and fear of falling, in elderly over 75 living at home. METHODS We performed a prospective study comparing two groups a group participating in day hospital (group "TPE") and a control group (group "Hospitalized") of elderly patient not receiving TPE recruited in short geriatric stays following a fall at home. RESULTS 28 patients in the "TPE" group and 20 patients in the "Hospitalized" group were included. The "TPE" group reported significantly better perceived quality of life at 3 months and 6 months. At 6 months, fear of falling was twice as high in the "Hospitalized" group than in the "TPE" group. CONCLUSIONS The group of subjects who was able to benefit from therapeutic education at home had an improved quality of life at 3 and 6 months and a decrease in the fear of falling at 6 months.The aim of this study was to describe the predictive role of the modified SEGA fragility score on nursing home admission, rehospitalization, falls and mortality. MATERIAL AND METHODS We performed a prospective, single-center cohort study in patients leaving geriatric hospitalization between July 2016 and February 2017, with follow-up at 6 months. Patients 65 years of age and over, returning home, were included. The primary outcome measure was admission to an institution at 6 months. We realized a Cox model to explore the predictive character of the variables. RESULTS Thirty-three patients (18.4%), mean age 80.9 years (± 6.5), were not very fragile. At 6 months, 13.5% of the fragile or very fragile patients and 1.2% of the patients who were not very fragile had entered the institution (p = 0.169). Fragility status was statistically significantly associated with rehospitalization at 3 months (p = 0.026) and single or multiple drop at 6 months) month (p = 0.003). CONCLUSION The SEGAm grid would predict the occurrence of derogatory events and improve return home.Music therapy is recommended in the treatment of Alzheimer's disease (AD) but only few tools exist to measure musical skills in AD patients. Our objective was to develop an assessment tool, the MOT (music therapy orientation test) designed to evaluate the musical cognitive abilities of patients and to guide the music therapy plan. This article presents the guidelines and scoring terms for all items, as well as the normal range in older patients. The MOT was administered to 50 healthy elderly subjects (mean, 74.3±8.7 years) and 50 AD patients (mean, 82.8±8.0 years). The diagnosis was based on DSM-IV consensus criteria and all patients had a MMSE score ≤27/30 (mean, 16.16±6.91). The results showed an average success rate to the MOT that was lower in AD compared to cognitively healthy subjects (respectively 22.6±8.3/34 versus 32.4±1/34, p less then 0.0001). The MOT score was positively correlated with the MMSE score (r=0.80, p less then 0.001). With a threshold of 30/34, the MOT sensitivity was 74%, its specificity 96% and its positive predictive value 94.
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