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The ability to select, isolate, and manipulate micron-sized particles or small clusters has made optical tweezers one of the emergent tools for modern biotechnology. In conventional setups, the classification of the trapped specimen is usually achieved through the acquired image, the scattered signal, or additional information such as Raman spectroscopy. In this work, we propose a solution that uses the temporal data signal from the scattering process of the trapping laser, acquired with a quadrant photodetector. Our methodology rests on a pre-processing strategy that combines Fourier transform and principal component analysis to reduce the dimension of the data and perform relevant feature extraction. Testing a wide range of standard machine learning algorithms, it is shown that this methodology allows achieving accuracy performances around 90%, validating the concept of using the temporal dynamics of the scattering signal for the classification task. Achieved with 500 millisecond signals and leveraging on methods of low computational footprint, the results presented pave the way for the deployment of alternative and faster classification methodologies in optical trapping technologies.During the last two years, the COVID-19 pandemic continues to wreak havoc in many areas of the world, as the infection spreads through person-to-person contact. Transmission and prognosis, once infected, are potentially influenced by many factors, including indoor air pollution. Particulate Matter (PM) is a complex mixture of solid and/or liquid particles suspended in the air that can vary in size, shape, and composition and recent scientific work correlate this index with a considerable risk of COVID-19 infections. Early Warning Systems (EWS) and the Internet of Things (IoT) have given rise to the development of Low Power Wide Area Networks (LPWAN) based on sensors, which measure PM levels and monitor In-door Air pollution Quality (IAQ) in real-time. This article proposes an open-source platform architecture and presents the development of a Long Range (LoRa) based sensor network for IAQ and PM measurement. A few air quality sensors were tested, a network platform was implemented after simulating setup topologies, emphasizing feasible low-cost open platform architecture.This paper presents a description of recent research and the multi-target tracking in experimental passive bistatic radar (PBR) system taking advantage of numerous non-cooperative AM radio signals via multi-static doppler shifts. However, it raises challenges for use by multiple spatially distributed AM radio illuminators for multi-target tracking in PBR system due to complex data association hypotheses and no directly used tracking algorithm in the practical scenario. this website To solve these problems, after a series of key array signal processing techniques in the self-developed system, by constructing a nonlinear measurement model, the novel method is proposed to accommodate nonlinear model by using the unscented transformation (UT) in Gaussian mixture (GM) implementation of iterated-corrector cardinality-balanced multi-target multi-Bernoulli (CBMeMBer). Simulation and experimental results analysis verify the feasibility of this approach used in a practical PBR system for moving multi-target tracking.Artificial Intelligence (AI) is one of the hottest topics in our society, especially when it comes to solving data-analysis problems. Industry are conducting their digital shifts, and AI is becoming a cornerstone technology for making decisions out of the huge amount of (sensors-based) data available in the production floor. However, such technology may be disappointing when deployed in real conditions. Despite good theoretical performances and high accuracy when trained and tested in isolation, a Machine-Learning (M-L) model may provide degraded performances in real conditions. One reason may be fragility in treating properly unexpected or perturbed data. The objective of the paper is therefore to study the robustness of seven M-L and Deep-Learning (D-L) algorithms, when classifying univariate time-series under perturbations. A systematic approach is proposed for artificially injecting perturbations in the data and for evaluating the robustness of the models. This approach focuses on two perturbations that are likely to happen during data collection. Our experimental study, conducted on twenty sensors' datasets from the public University of California Riverside (UCR) repository, shows a great disparity of the models' robustness under data quality degradation. Those results are used to analyse whether the impact of such robustness can be predictable-thanks to decision trees-which would prevent us from testing all perturbations scenarios. Our study shows that building such a predictor is not straightforward and suggests that such a systematic approach needs to be used for evaluating AI models' robustness.Conventional predictive Artificial Neural Networks (ANNs) commonly employ deterministic weight matrices; therefore, their prediction is a point estimate. Such a deterministic nature in ANNs causes the limitations of using ANNs for medical diagnosis, law problems, and portfolio management in which not only discovering the prediction but also the uncertainty of the prediction is essentially required. In order to address such a problem, we propose a predictive probabilistic neural network model, which corresponds to a different manner of using the generator in the conditional Generative Adversarial Network (cGAN) that has been routinely used for conditional sample generation. By reversing the input and output of ordinary cGAN, the model can be successfully used as a predictive model; moreover, the model is robust against noises since adversarial training is employed. In addition, to measure the uncertainty of predictions, we introduce the entropy and relative entropy for regression problems and classification problems, respectively. The proposed framework is applied to stock market data and an image classification task. As a result, the proposed framework shows superior estimation performance, especially on noisy data; moreover, it is demonstrated that the proposed framework can properly estimate the uncertainty of predictions.Classification is a fundamental task for airborne laser scanning (ALS) point cloud processing and applications. This task is challenging due to outdoor scenes with high complexity and point clouds with irregular distribution. Many existing methods based on deep learning techniques have drawbacks, such as complex pre/post-processing steps, an expensive sampling cost, and a limited receptive field size. In this paper, we propose a graph attention feature fusion network (GAFFNet) that can achieve a satisfactory classification performance by capturing wider contextual information of the ALS point cloud. Based on the graph attention mechanism, we first design a neighborhood feature fusion unit and an extended neighborhood feature fusion block, which effectively increases the receptive field for each point. On this basis, we further design a neural network based on encoder-decoder architecture to obtain the semantic features of point clouds at different levels, allowing us to achieve a more accurate classification. We evaluate the performance of our method on a publicly available ALS point cloud dataset provided by the International Society for Photogrammetry and Remote Sensing (ISPRS). The experimental results show that our method can effectively distinguish nine types of ground objects. We achieve more satisfactory results on different evaluation metrics when compared with the results obtained via other approaches.Mineral excavation is a common process throughout the world. The open pits remaining after the closure of a mine require well-considered and meticulous reclamation activities aimed at restoring the environmental properties of a given area. The inspections carried out in Poland indicate numerous irregularities in implementing the reclamation process. The research in this study was conducted in six measurement series and includes both chemical and olfactometry determinations by devices multisensor portable gas detector and field olfactometer. Statistical analysis of the results obtained show high concentrations in ambient air of both chemical compounds (NH3, VOCs, H2S, CH3SH) and odour, excluding the possibility of occurrence in the pit of only waste types contained in the administrative decision on reclamation. In addition to the unpleasant odour, the listed compounds can have dangerous effects on the health and life of living organisms. This paper presents a suitable method of control and detection of irregularities in the conducted processes. The main advantage is the relatively low cost of purchasing sensors and field olfactometers compared to other devices, and the possibility to test the polluted air in situ, without the risk of chemical processes occurring during transport of gas samples to the laboratory.The extent to which muscle synergies represent the neural control of human behavior remains unknown. Here, we tested whether certain sets of muscle synergies that are fundamentally necessary across behaviors exist. We measured the electromyographic activities of 26 muscles, including bilateral trunk and lower limb muscles, during 24 locomotion, dynamic and static stability tasks, and we extracted the muscle synergies using non-negative matrix factorization. Our results show that 13 muscle synergies that may have unique functional roles accounted for almost all 24 tasks by combinations of single and/or merging of synergies. Therefore, our results may support the notion of the low dimensionality in motor outputs, in which the central nervous system flexibly recruits fundamental muscle synergies to execute diverse human behaviors. Further studies are required to validate the neural representation of the fundamental components of muscle synergies.Multirotor unmanned aerial vehicles (MUAVs) are becoming more prominent for diverse real-world applications due to their inherent hovering ability, swift manoeuvring and vertical take-off landing capabilities. Nonetheless, to be entirely applicable for various obstacle prone environments, the conventional MUAVs may not be able to change their configuration depending on the available space and perform designated missions. It necessitates the morphing phenomenon of MUAVS, wherein it can alter their geometric structure autonomously. This article presents the development of a morphed MUAV based on a simple rotary actuation mechanism capable of driving each arm's smoothly and satisfying the necessary reduction in workspace volume to navigate in the obstacle prone regions. The mathematical modelling for the folding mechanism was formulated, and corresponding kinematic analysis was performed to understand the synchronous motion characteristics of the arms during the folding of arms. Experiments were conducted by precisely actuating the servo motors based on the proximity ultrasonic sensor data to avoid the obstacle for achieving effective morphing of MUAV. The flight tests were conducted to estimate the endurance and attain a change in morphology of MUAV from "X-Configuration" to "H-Configuration" with the four arms actuated synchronously without time delay.
My Website: https://www.selleckchem.com/Proteasome.html
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