Notes

About three Arginine-Rich Cell-Penetrating Proteins Aid Mobile Internalization of Red-Emitting Quantum Dots.
Combined effect of multiple metals could not be ignored, in which As and Cd contributed over 80% to total non-carcinogenic risks for adults and children.The influence of long-term fertilization on soil microbial communities is critical for revealing the association between belowground microbial flora and aboveground crop productivity-a relationship of great importance to food security, environmental protection, and ecosystem functions. Here, we examined shifts in soil chemical properties, microbial communities, and the nutrient uptake and yield of rice subjected to different chemical and organic fertilization treatments over a 40-year period in red paddy soil. Ten different treatments were used a control without fertilizer, and applications of nitrogen (N), phosphorus (P), potassium (K), NP, NK, PK, NPK, double NPK, or NPK plus manure. Compared with the effects of withholding one or two nutrients (N, P, or K), the balanced application of chemical NPK and organic fertilizers markedly improved soil nutrient status and rice yield. This improvement of soil fertility and rice yield was not associated with bacterial, archaeal, or fungal alpha diversities. The bacteertility and rice yield in red paddy soil.Food waste (FW) and sewage sludge (SS) were anaerobically co digested under solid state conditions (Total solids >15%) and observed that mixing ratio of 31 and 21 is optimum for mesophilic and thermophilic conditions respectively. The VS reduction and methane yield at optimized ratio was 76% and 0.35 L CH4/(g VS reduced) respectively at mesophilic temperature whereas it was 88% and 0.42 L CH4/(g VS reduced) at thermophilic temperature. The metagenomic analysis for these cases were done and high throughput DNA sequencing revealed that diversified bacterial groups that participate in the different metabolisms (hydrolysis, acidogenesis and acetogenesis) were mainly dominated by the phylum Firmicutes and Bacteriodetes. Genus Methanothrix is found to be dominant which is capable of generating methane by any methanogenic pathway among all the archaeal communities in the reactors followed by Methanolinea and Methanoculleus. However, it was understood through metagenomic studies that acetotrophic pathway is observed to be the major metabolic pathway in the reactors.Plastic gauzes have been widely used in the BTH region against haze events and for agricultural practices. The breakage of plastic gauzes would lead to the release of microplastics into soils, but it is difficult to estimate the inputs due to their wide implementation. In this study, we have conducted an estimation model based on the remote sensing technology for plastic gauze identification and the data from field experiments and literature. This model first managed to interpret the distribution of plastic gauzes from the Landsat8 images with the average overall accuracy at 0.92 and the average kappa at 0.77. By deeming the implementation duration of plastic gauzes from their distribution and using the breakage rates of plastic materials in soils reported in the literature, the model estimated that on average 1629.68 tons of microplastics have been released to soils from plastic gauze annually in the BTH region. Comparing with the microplastics released from other sources (e.g., personal care products, household dusts, laundry, and tire wear), plastic gauze could be a considerable contributor to soil microplastics.Complicated ligand-dependent signaling pathways of bisphenol A (BPA) and its analogues involve not only intranuclear estrogen receptor but also membrane receptor G protein-coupled estrogen receptor (GPER). However, the structural basis for molecular recognition of GPER by the environmental chemicals remains unknown. To reveal the structural dependence of GPER recognition by bisphenols, a systematic molecular dynamics simulation study was performed for selected bisphenols with different electron hybrid orbitals and substituents on their C atoms connecting two phenol rings. BPA was used as a control, bisphenol C(BPC) as an example for a connecting C with sp2 hybrid orbitals to provide more ligand rigidity, bisphenol E(BPE) and bisphenol F(BPF) for decreased steric hindrance and hydrophobicity around the connecting C, and bisphenol B(BPB) and bisphenol AF(BPAF) for increased hydrophobicity and steric hindrance. All the tested bisphenols can bind with GPER at its classic orthosteric site to obtain GPER-ligand comnsistent with the available experimental observations.This study inter-compared the concentration and chemical characteristics of PM2.5 at two harbors in East Asia, and identified the potential sources of PM2.5 and their contribution. Two sites located at the Kaohsiung (Taiwan) and Manila (the Philippines) Harbors were selected for simultaneous sampling of PM2.5 in four seasons. The sampling of 24-h PM2.5 was conducted for continuous seven days in each season. Water-soluble ions, metallic elements, carbonaceous content, anhydrosugars, and organic acids in PM2.5 were analyzed to characterize their chemical fingerprints. Receptor modeling and trajectory simulation were further applied to resolve the source apportionment of PM2.5. The results indicated that the Kaohsiung Harbor was highly influenced by long-range transport (LRT) of polluted air masses from Northeast Asia, while the Manila Harbor was mainly influenced by local emissions. Secondary inorganic aerosols were the most abundant ions in PM2.5. Crustal elements dominated the metallic content of PM2.5, but trace elements were mainly originated from anthropogenic sources. Higher concentrations of organic carbon (OC) than elemental carbon (EC) was found in PM2.5, with secondary OC (SOC) dominant to the former. Levoglucosan in PM2.5 at the Manila Harbor were superior to those at the Kaohsiung Harbor due to biomass burning surrounding the Manila Harbor. Additionally, high mass ratios of malonic and succinic acids (M/S) in PM2.5 indicated the formation of SOAs. Overall, the ambient air quality of Manila Harbor was more polluted than Kaohsiung Harbor. The Kaohsiung Harbor was more severely affected by LRT of polluted air masses from Northeast Asia, while those toward the Manila Harbor came from the oceans. The major sources resolved by CMB and PMF models at the Kaohsiung Harbor were secondary aerosols, ironworks, incinerators, oceanic spray, and ship emissions, while those at the Manila Harbor were secondary aerosols, soil dust, biomass burning, ship emissions, and oceanic spray.Since graphene is currently incorporated into various consumer products and used in a variety of applications, determining the relationships between the physicochemical properties of graphene and its toxicity is critical for conducting environmental and health risk analyses. Data from the literature suggest that exposure to graphene may result in cytotoxicity. However, existing graphene toxicity data are complex and heterogeneous, making it difficult to conduct risk assessments. Here, we conducted a meta-analysis of published data on the cytotoxicity of graphene based on 792 publications, including 986 cell viability data points, 762 half maximal inhibitory concentration (IC50) data points, and 100 lactate dehydrogenase (LDH) release data points. Models to predict graphene cytotoxicity were then developed based on cell viability, IC50, and LDH release as toxicity endpoints using random forests learning algorithms. The most influential attributes influencing graphene cytotoxicity were revealed to be exposure dose and detection method for cell viability, diameter and surface modification for IC50, and detection method and organ source for LDH release. The meta-analysis produced three sets of key attributes for the three abovementioned toxicity endpoints that can be used in future studies of graphene toxicity. The findings indicate that rigorous data mining protocols can be combined with suitable machine learning tools to develop models with good predictive power and accuracy. The results also provide guidance for the design of safe graphene materials.Denitrifying phosphorus removal (DPR) technology is one of the most effective approach to simultaneously realize nitrogen (N) and phosphorus (P) removal from low COD/N ratio wastewater. Identifying the interaction of denitrifying phosphate-accumulating organisms (DPAOs), denitrifying glycogen organisms (DGAOs) and denitrifying ordinary heterotrophic organisms (DOHOs) is critical for optimizing denitrification and anoxic P uptake efficiency in DPR processes. In this study, a novel DPR system of anaerobic anoxic oxic - biological contact oxidation (AAO-BCO) was employed to dispose actual sewage with various influent COD/N ratios (3.5-6.7). High efficiency of TIN (76.5%) and PO43--P (94.4%) removal was observed when COD/N ratio was between 4.4 and 5.9. At the COD/N ratio of 5.7 ± 0.2, prominent DPR performance was verified by the superior DPR efficiency (88.7%) and anoxic phosphorus uptake capacity (PUADPAOs/ΔTIN = 1.84 mg/mg), which was further proved by the preponderance of DPAOs in C, N and P removal pathways. this website GAOs have a competitive advantage over PAOs for COD utilization at low COD/N ratio of 3.7 ± 0.2, which further limited the N removal efficiency. High proportion of N removal via DOHOs (21.2%) at the COD/N ratio of 6.5 ± 0.2 restrained the DPR performance, which should be attributed to the outcompete of DOHOs for NO3-. The nutrient removal mechanisms were explicated by stoichiometric calculation methodology to quantify the contribution of diverse functional microorganisms, contributing to improving the robustness of AAO-BCO system when facing the fluctuation of influent carbon source concentration.Soil organic carbon (SOC), as the largest terrestrial carbon pool, plays an important role in global carbon (C) cycling, which may be significantly impacted by global changes such as nitrogen (N) fertilization, elevated carbon dioxide (CO2), warming, and increased precipitation. Yet, our ability to accurately detect and predict the impact of these global changes on SOC dynamics is still limited. Investigating SOC responses to global changes separately for mineral-associated organic carbon (MAOC) and the particulate organic carbon (POC) can aid in the understanding of overall SOC responses, because these are formed, protected, and lost through different pathways. To this end, we performed a systematic meta-analysis of the response of SOC, MAOC, and POC to global changes. POC was particularly responsive, confirming that it is a better diagnostic indicator of soil C changes in the short-term, compared to bulk SOC and MAOC. The effects of elevated CO2 and warming were subtle and evident only in the POC fraction (+5.11% and - 10.05%, respectively), while increased precipitation had no effects at all. Nitrogen fertilization, which comprised the majority of the dataset, increased SOC (+5.64%), MAOC (+4.49%), and POC (+13.17%). Effect size consistently varied with soil depth and experiment length, highlighting the importance of long-term experiments that sample the full soil profile in global change SOC studies. In addition, SOC pool responses to warming were modified by degree of warming, differently for air and soil warming manipulations. Overall, we suggest that MAOC and POC respond differently to global changes and moderators because of the different formation and loss processes that control these pools. Coupled with additional plant and microbial measurements, studying the individual responses of POC and MAOC improves understanding of the underlying dynamics of SOC responses to global change. This will help inform the role of SOC in mitigating the climate crisis.
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