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Hypotony-associated Problems Soon after Deep Sclerectomy: Chance, Risks, and Long-term Outcomes.
CU hospitalization. • A unique music therapy intervention should be designed for preterm infants with severe brain injury and their mothers.Two cases of myopericytosis combined with pericytoma originating within the lung are reported. These are rare pulmonary tumors. The differential diagnosis for hemangiopericytoma and pericytic tumors with glomus elements is discussed. Both myopericytic lesions mimic other lesions, which are more commonly seen in the lung. Based on the expression of vascular growth factor receptors 2 and 3, an antiangiogenic therapy was suggested for the patient with the myopericytoma. A treatment with an angiogenesis inhibitor resulted in a regression of the tumor, but not the precursor lesion. Probably a more specific therapy using tyrosine kinase inhibitors for VEGFR2/3 might better control these myopericytic proliferations.Osseous remains provide forensic anthropologists with morphological and osteometric information that can be used in building a biological profile. By conducting a visual and physical examination, an anthropologist can infer information such as the sex and age of the deceased. Traditionally, morphological and osteometric information is gathered by physically handling remains for analysis. With the advancement of digital technology, there has been a shift from direct to indirect methods of analysis by utilizing models generated from three-dimensional (3D) imaging, which includes computed tomography (CT) scanning and 3D photogrammetry. Although CT scanning is more common, photogrammetry has found application in a range of fields such as architecture, geography and road accident reconstruction. The application of modern-day photogrammetry for forensic anthropology purposes, however, has not been discussed extensively. The aim of this research was to validate the accuracy of 3D models generated by photogrammetry by comparing them to both 3D models generated by CT scanning and the actual physical models. In this study, six 3D models were created using photogrammetry (n = 3) and CT scanning (n = 3). The 3D models were generated from three different Bone Clone® human skulls. A mobile phone camera was used to capture images, which were then processed in Agisoft Metashape®. MEK inhibitor drugs Intrarater, interrater, and intermethod reliability tests gave correlation coefficients of at least 0.9980, 0.9871, and 0.9862, respectively; rTEM results ranged from 0.250 to 6.55%; and an analysis of variance (ANOVA) yielded P values under 0.05 for all measurements except one. Statistical tests therefore showed photogrammetry to be a reliable and accurate alternative to more expensive CT scanning approaches.
The aim of this study was to assess the filling quality of five obturation techniques in oval-shaped root canals.

A total of 212 mandibular first molars with one distal oval canal were selected. Distal canals, shaped with WaveOne Gold Primary, were randomly divided in five groups (n = 40) for obturation continuous wave condensation, GuttaCore, Thermafil, single cone with AH plus, and single cone with BioRoot RCS. The proportions of gutta-percha-filled areas (GPFA), sealer-filled areas (SFA), void areas (VA), and the sealer/gutta tags into dentinal tubules at 4mm and 2mm from the apex were analyzed by an optical numeric microscope, SEM, and energy-dispersive X-ray (EDX). Data were then compared by Kruskal-Wallis one-way ANOVA on ranks (α = 0.05).

At 4mm, a statistically significant higher GPFA and lower SFA were observed in the GuttaCore and Thermafil groups compared with the 3 other groups. A statistically significant lower VA was observed in the continuous wave condensation, GuttaCore, and Thermafil groups than in the two single-cone groups. At 2mm, there were a statistically significant higher GPFA and lower SFA and VA in GuttaCore and Thermafil groups than in the 3 other groups. At the two levels investigated, the presence of gutta-percha tags was clearly demonstrated for GuttaCore and Thermafil groups; no tags were observed in the 3 other groups.

Obturation quality was overall improved in GuttaCore and Thermafil groups.

Carrier-based techniques may significantly improve the filling quality compared to continuous wave condensation and single-cone technique. The single-cone technique might have inherent limitations especially in oval root canals regardless of the sealer used.
Carrier-based techniques may significantly improve the filling quality compared to continuous wave condensation and single-cone technique. The single-cone technique might have inherent limitations especially in oval root canals regardless of the sealer used.
The safety of upper gastrointestinal cancer patients in the SARS-CoV-2 outbreak is extremely important and most surgeons need to establish a contingency management.

In this study, we present the surgical outlines of patients suffering from upper gastrointestinal cancers.

Data were obtained from PubMed, Cochrane Database of Controlled Trials, and SCOPUS of reports up to September 2020.

The COVID-19 outbreak makes surgical procedures extremely difficult to be performed. The most common criteria to prioritize patients for surgical treatment are stage, tumor biology, presence of tumor-related symptoms, the risk of tumor to become non-resectable, and time interval from neoadjuvant therapy. The multidisciplinary teams can help assigning a priority level to each clinical case.

We have to continue providing treatment to oncologic patients in the face of COVID-19 uncertainty, with higher caution and responsibility in order to develop a safer and more effective personalized treatment plan.
We have to continue providing treatment to oncologic patients in the face of COVID-19 uncertainty, with higher caution and responsibility in order to develop a safer and more effective personalized treatment plan.
Small intestinal neuroendocrine tumours (siNETs) with a Ki-67 proliferation index between 3 and 20% belong to WHO grade 2. Response to treatment may be monitored by blood chromogranin A (CgA) and urine 5-hydroxyindoleacetic acid (5HIAA). The aim of this retrospective study was to investigate the prognostic value of baseline CgA and 5HIAA and of the early biochemical response to treatment, and to compare different cut-off values used in the literature.

A retrospective cohort study of 184 patients with siNET Grade 2 treated with somatostatin analogues (SSA), interferon-alpha (IFN) or peptide receptor radionuclide therapy (PRRT).

Baseline CgA was a statistically significant prognostic marker for both cancer-specific survival (CSS) and progression-free survival (PFS). A cut-off of 5 × ULN (upper limit of normal) was best discriminative in most cases, but 2 × ULN discriminated better for SSA. Baseline 5HIAA was a prognostic marker for CSS in treatment with IFN and PRRT, but not for single SSA. Early changes of CgA and 5HIAA correlated well with CSS (HR 3.
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