Notes

The particular shot, the content, and the courier: COVID-19 vaccine acceptance within South america.
Research examining the associations between emotions and goal-directed behaviors has mainly relied on between-subjects designs even though much of the advice based on these findings focus on within-individual changes. The purpose of this study was to better understand intraindividual daily associations between emotions and effort in the context of college students' academic goal striving. In Study 1 (2,531 daily reports from 194 college students at a competitive university), daily positive emotions related to goal pursuit were associated with reduced time spent on the goal the next day (i.e., coasting). In contrast, daily negative emotions were associated with increased time spent on the goal the next day (i.e., pushing), particularly for students with high self-control. In Study 2 (338 daily reports from 80 college students in diverse universities), feeling pride was linked to coasting on the next day. Feeling shame was unrelated to changes in next-day effort among students with high self-control, but predicted decreased next-day effort among students with low self-control. Taken together, the findings suggest that goal pursuers may be less likely to expend effort after the day they feel certain positive emotions (e.g., pride) about their goal progress. Furthermore, the association between negative emotions and pushing may be heterogeneous depending on individual characteristics such as self-control. (PsycInfo Database Record (c) 2020 APA, all rights reserved).Pavlovian conditioning studies have shown that humans can generalize conditioned fear to novel stimuli that are categorically related to the threat cue, despite perceptual dissimilarities. The current work examined the role of trait anxiety in the generalization of fear to categorically related objects. Items from 1 category, breakfast or bakery, were paired with shock whereas items from the other category were not. Participants were then tested on ambiguous cross-classified items-those that fitted in both the threat and safe categories. No trait anxiety effect was found in generalization to novel stimuli that clearly belonged to either the threat or the safe category in either shock expectancy ratings or skin conductance. In contrast, trait anxious individuals showed a bias toward higher threat appraisal to the ambiguous cross-classified stimuli. However, this pattern was not due to trait anxious individuals being more likely to perceive ambiguous items as belonging to the threat category. Instead they appear to display a bias toward overestimation of threat when the threat level is ambiguous. The current findings indicate that threat ambiguity modulates the effect of trait anxiety on categorical fear generalization. (PsycInfo Database Record (c) 2020 APA, all rights reserved).OBJECTIVE Posttraumatic stress disorder (PTSD) is associated with increased risk for cardiometabolic disease. Clinically meaningful PTSD improvement is associated with a lower risk for diabetes, but it is not known if similar associations exist for incident hypertension, hyperlipidemia, and clinically relevant weight loss (i.e., ≥5% loss). METHOD Medical record data from Veterans Health Affairs patients with clinic encounters between fiscal year (FY) 2008 to 2015 were used to identify patients with worsening or no PTSD improvement (i.e., PTSD checklist (PCL) score decrease less then 10), small (10-19 point PCL decrease), and large (≥20 point PCL decrease) PTSD improvement. To estimate the association between degree of PTSD improvement and incident hypertension (n = 979), incident hyperlipidemia (n = 1,139) and incident ≥5% weight loss (1,330), we computed Cox proportional hazard models, controlling for confounding using inverse probability of exposure weighting (IPEW). RESULTS Overall, patients were about 40 years of age, 80% male and 65% White. Worsening or no PCL change occurred in about 60%, small improvement in 20%, and large improvement in 20%. After weighting data, compared with worsening or no change, both small and large PTSD improvements were associated, albeit not significantly, with lower risks for hypertension (HR = 0.68; 95% confidence interval, CI [0.46, 1.01] and HR = 0.79; 95% CI [0.53, 1.18], respectively). In weighted data, PTSD improvement was not associated with incident hyperlipidemia or ≥5% weight loss. CONCLUSIONS We observed limited evidence for an association between PTSD improvement and decreased hypertension risk. PCL decreases were not associated with hyperlipidemia or ≥5% weight loss. Further studies that measure potential physical health benefits of change in specific PTSD symptoms are needed. (PsycInfo Database Record (c) 2020 APA, all rights reserved).Despite early theorists suggesting that psychopathic traits are associated with higher intelligence, meta-analytic work has found that global psychopathy scores are actually negatively related to intelligence, albeit weakly. Furthermore, it was reported in the same meta-analytic work that the various dimensions of psychopathy were differentially related to intelligence. Importantly, virtually all of the research to date has relied on cross-sectional associations. The current study examined whether intelligence scores (verbal comprehension, nonverbal IQ, and a global intelligence composite) at age 8 were associated with psychopathy scores at age 48 in a sample of White, urban male individuals from London (analytical n = 292). Results suggested a significant, but weak, inverse association between intelligence and the affective, lifestyle, and antisocial facets of psychopathy and a nonsignificant association with the interpersonal facet, as assessed by the Psychopathy Checklist Screening Version. These findings contribute to the growing body of evidence suggesting that psychopathy, as conceptualized in most modern models, is either very weakly inversely related to or simply not a correlate of intelligence. (PsycInfo Database Record (c) 2020 APA, all rights reserved).Early life stress negatively impacts behavior and underlying neural circuitry across species. The present study investigated the effects of nutritional stress (NS), which increases parental foraging, on song quality in males, song preferences in females, and the size and number of cells in song and auditory regions of the zebra finch brain. We hypothesized that NS would decrease song quality in males and decrease preference for high quality song in females. Furthermore, we predicted that NS would reduce the size of song nuclei and decrease the number of cells in song and auditory regions. In males, NS decreased the number of syllable types (a measure of song complexity), decreased the number of high notes and flat notes, and increased the number of noisy notes, but had no effect on song rate or song length. In females, NS reduced preferences for high quality song. Despite these behavioral effects, there were no effects of NS on song and auditory nuclei, although there were effects of age and sex. These results suggest that NS affects behavior in both males and females, but these effects are not attributable to the number of cells or size of song and auditory regions. Such findings add to our understanding of the effects of early life stress on behavior and cognition. (PsycInfo Database Record (c) 2020 APA, all rights reserved).Depression affects both women and men, but women are 2 times more susceptible to the incidence of depression. Although a number of studies report sex differences in stress responses, it remains unclear which animal models of depression can better mimic the sex difference in human depression. The majority of stress models used male rodents whereas fewer studies included females. The aims of this study were to determine which rat stress models mimic the sex difference in depression and to identify sex-specific risk factors for depression model-induced depression-like behaviors. Here, we compared subchronic variable stress (SCVS) and chronic unpredictable mild stress (CUMS) models to evaluate the susceptibility versus resilient phenotypes in male and female rats. SCVS induced depression-like behaviors in female rats only. The CUMS paradigm was more likely to induce depression-like behaviors in male rats. Furthermore, to explore the underlying mechanisms, we used quantitative reverse transcriptase polymerase chairats. (PsycInfo Database Record (c) 2020 APA, all rights reserved).Postnatal administration of high-fat, low-carbohydrate ketogenic diets (KDs) is an established and effective treatment option for refractory epilepsy, with more recently identified therapeutic potential across a wide range of preclinical models of neurological and psychiatric disorders. However, the impact of gestational exposure to a KD (GKD) on offspring development remains unclear. Previous work has found that GKD exposure reduces depression- and anxiety-like behaviors in CD-1 mice, whereas postnatal KD improves sociability in several different rodent models of autism. Here we examined how sociability is impacted by GKD. Given that the neuropeptide oxytocin positively regulates affect, anxiety, and sociability, we also examined the effects of GKD on brain oxytocin expression. Male and female CD-1 mice exposed to either a standard diet (SD) or a KD gestationally were cross-fostered with SD dams at birth and remained on a SD from that point onward. These offspring were then tested for sociability and social novelty (three-chambered test) and depressive-like behaviors (forced swim test) at 10 weeks of age. At the conclusion of testing, brain tissue was collected and immunohistochemically processed for oxytocin expression in hypothalamic and limbic areas. We found that GKD increased sociability and reduced depressive-like symptoms, without affecting oxytocin expression in quantified areas. By expanding the scope of the lasting impact of gestational exposure to a ketogenic diet to include positive effects on sociability, these results indicate that GKDs may have novel therapeutic applications for individuals at risk for developmental disorders of social behavior, including autism and schizophrenia. (PsycInfo Database Record (c) 2020 APA, all rights reserved).From employees' point of view, changes in ethical leadership perceptions can signal important changes in the nature of the employment relationship. Guided by social exchange theory, this study proposes that changes in ethical leadership perceptions shape how employees appraise their exchange relationship with the organization and affect their pride in or contempt for the organization. AG-1478 solubility dmso Changes in these associative/dissociative emotions, in turn, precipitate changes in behaviors that serve or hurt the organization, notably voice and turnover. Experimental data collected from 900 subjects (Study 1) and field data collected from 470 employees across 4 waves over 14 months (Study 2) converged to show that changes in ethical leadership perceptions were related to same-direction changes in employees' pride in the organization and to opposite-direction changes in their contempt for the organization above and beyond the effect of the present ethical leadership level. Changes in pride were in turn related to same-direction changes in functional voice, whereas changes in contempt were related to same-direction changes in dysfunctional voice. The field study also provided evidence that when pride increased (decreased), employees were less (more) likely to leave the organization 6 months after. These results suggest that changes in ethical leadership perceptions are meaningful on their own, that they may alter employees' organization-targeted behaviors, and that changes in associative/dissociative emotions are the mediating mechanism. (PsycInfo Database Record (c) 2020 APA, all rights reserved).
My Website: https://www.selleckchem.com/products/ag-1478-tyrphostin-ag-1478.html