Notes

Left-handed cardiac looping through mobile chirality is actually mediated simply by position-specific convergent extensions.
BACKGROUND Phacoemulsification surgery has the ability to deeply alter the segment anterior morphology, especially in eye with shallow anterior chamber (AC), narrow anterior chamber angle (ACA). However, the changes of anterior chamber depth (ACD) and ACA on the close angle suspect eyes after phacoemulsification have not been mentioned in many studies. So, we conduct this research. AIM To evaluate the alteration in the ACA and ACD after phacoemulsification in the close angle suspect eyes. METHODS Interventional study with no control group. Subjects were the primary angle closure suspect (PACS) eyes, that were operated by phacoemulsification with intraocular lens (IOL) at Glaucoma Department of VNIO from December 2017 to October 2018. RESULTS 29 PACS eyes with cataract were operated by phacoemulsification with intraocular lens. After 3 months of monitoring, the average ACD augmented from 2.082 ± 0.244 to 3.673 ± 0.222 mm. AOD500 increase from 0.183 ± 0.088 to 0.388 ± 0.132 μm, AOD750 increased from 0.278 ± 0.105 to 0.576 ± 0.149 μm. The TISA500 enlarged from 0.068 ± 0.033 to 0.140 ± 0.052 mm2, TISA750 enlarged from 0.125 ± 0.052 to 0.256 ± 0.089 mm2 at the third month (p less then 0.01). selleck inhibitor CONCLUSION Phacoemulsification surgery increases the ACD and enlarged the angle in the PACS eyes. Copyright © 2019 Anh Tuan Vu, Van Anh Bui, Hai Long Vu, Do Quyet, Than Van Thai, Vu Thi Nga, Toi Chu Dinh, Nguyen Duy Bac.BACKGROUND Dry eye (DE) can effect on quality of life by pain, inability to perform certain activities that require prolonged attention (driving, reading,…) and productivity at work and finally effect to Q0L associated with DE. OSDI is scale questionnaire is created team to measure the quality of life related to ocular surface disease. AIM To describe the dry eye disease according to OSDI scale and related factors of this disease. METHODS A cross-sectional descriptive study was carried out on outpatients (≥ 16-year-old) who were examined and diagnosed with dry eyes at Vietnam National Institute Of Ophthalmology from April to July 2018. Data was collected using the OSDI questionnaire. RESULTS The average age of participants was 44.6 years; 80.9% of patients were female; 39.9% were identified having mild dry eye. The related factors have been identified that associated with severe dry eye, including age OR = 1.03 (95% CI 1.01-1.05, p = 0.005), binocular good vision OR = 0.11 (95% CI 0.05-0.23; p less then 0.0001), medical history OR = 17.09 (95% CI 2.24-130.25; p less then 0.0001), chronic conjunctivitis OR = 0.36 (95% CI 0.14-0.91; p = 0.027), refractive errors OR = 0.14 (95% CI 0.04-0.48; p less then 0.0001), Sjogren's syndrome OR = 31.13 (95% CI 7.08-136.76; p less then 0.0001). CONCLUSION Several related factors have been identified associated with severe dry eye, including age, binocular good vision, medical history, chronic conjunctivitis, refractive errors, Sjogren's syndrome. Copyright © 2019 Bui Thi Van Anh, Pham Thanh Thuy, Nguyen Thi Bich Ngoc, Nguyen Thi Thu Hien, Pham Hai Yen, Do Quyet, Than Van Thai, Vu Thi Nga, Nguyen Duy Bac.BACKGROUND Keratoconus is an ectatic corneal disorder that can impair the visual acuity. Up to now, penetrating keratoplasty (PK) remains the most common surgical procedure to treat severe keratoconus. In Vietnam, most keratoconus patients come to visit doctor at severe stage and were treated by PK, so we conduct this study. AIM To evaluate the results of PK for keratoconus in Vietnamese patients. METHODS This was a retrospective study of 31 eyes with keratoconus who underwent PK in VNIO from January 2005 to December 2014. RESULTS The average visual acuity was 0.86 ± 0.37 logMAR (20/145). In the group of patients without amblyopia, best spectacle-corrected visual acuity of 20/60 or better was recorded in 75.9% of eyes and 93.1% of eyes achieved a best corrected visual acuity with hard contact lenses of 20/40 or better. Mean postoperative corneal power was 43.8 ± 4.5D. Mean corneal astigmatism was 5.9 ± 2.7D. 94.6% of grafts remained clear. Posterior subcapsular cataract developed in 22.6% of eyes. Graft rejection was recognized in 12.9% of eyes. CONCLUSION PK is an effective procedure with high rate of graft survival for keratoconus patients. However, patients should be aware of the necessary of optical correction to gain the best VA after surgery. Copyright © 2019 Le Xuan Cung, Duong Mai Nga, Nguyen Dinh Ngan, Nguyen Xuan Hiep, Do Quyet, Than Van Thai, Vu Thi Nga, Toi Chu Dinh, Nguyen Duy Bac.BACKGROUND Myopia is most prevalent type of refraction error. In some Asian countries, the prevalence of myopia can be 80 - 90% in the population aged 17 - 18. AIM To analyze the correlation between ocular biometric indices and refraction status in Vietnamese young myopes. METHODS A prospective cross - section study was conducted in young myopes. Data on axial length, central cornea thickness, corneal topography & anterior chamber depth and spherical equivalent were collected. Independent Sample T Test and ANOVA test were used to compare between groups. The correlations between ocular biometry and myopic spherical equivalent refraction were examined by Pearson Correlation with the level of significance p less then 0.05. RESULTS Totally, 418 eyes from 209 patients were recruited. The average axial length, central cornea thickness, cornea refraction & anterior chamber depth were 25.68 ± 1.09 mm, 539.78 ± 32.665 µm, 43.16 ± 1.369 D, 3.30 ± 0.243 mm, respectively. The correlation between axial length and spherical equivalent refraction (SER) was high (r = - 0.742, p less then 0.0001) while those between central cornea thickness and cornea refraction were negligible (r = - 0.107, p = 0.029; r = -0.123, p = 0.012; respectively). There was no correlation between anterior chamber depth and spherical equivalent refraction (r = 0.019, p = 0.697). CONCLUSION Among ocular biometric indices, axial length was significantly correlated with spherical equivalent of young adult patients. Copyright © 2019 Hien Thi Thu Nguyen, Dung Thi Thanh Nguyen, Dong Ngoc Pham, Anh Phuong Tran, Do Quyet, Than Van Thai, Vu Thi Nga, Nguyen Duy Bac.
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