Notes

Association of Cerebral Ischemia With Corneal Nerve Loss and also Brain Atrophy throughout MCI as well as Dementia.
Wastewater reclamation and reuse is a sustainable solution for alleviating the scarcity of water resources. However, the potential risks resulting from the residual pollutants in reclaimed water are of concern. Identifying of priority pollutants would be a practical approach for the management and scientific evaluation of risks associated with reclaimed water reuse. In this study, a novel risk score-based method is proposed for prioritizing residual pollutants in reclaimed water. First, target the specific applications and possible scenarios of reclaimed water as well as recognize the potential receptors and exposure pathways. Second, determine exposure and effect parameters, and assign values to every parameter. Third, calculate the total exposure score and effect score for each pollutant using a weighted method, then calculate the risk score by multiplying total exposure score and effect score, and rank all pollutants based on their risk scores from high to low. Fourth, recommend a priority pollutants list for reclaimed water reuse. To demonstrate the procedure and validate the method, a case study on groundwater recharge with reclaimed water was conducted. In the case study, EE2 and E2, which have also been listed in other recent water quality standards, were identified as priority pollutants. The case study illustrated sufficient reliability, great discrimination and feasibility of the method. The five exposure parameters and seven effect parameters in this method can objectively evaluate the potential risk of pollutants and identify priority pollutants for the specific application of reclaimed water. This application-oriented and risk-based prioritization method is easy to understand and simple to operate in practice. This study fills existing gaps by proffering a novel prioritization method to identify priority pollutants in reclaimed water for an accurate evaluation and safety management of recycled wastewater.Carbon capture and storage (CCS) is one of the key technologies and measures for the energy transition towards achieving the climate targets. Accounting for the high uncertainty, risks, and irreversibility of CCS projects, a growing number of studies apply the real options (RO) approaches which allow flexibility in the valuation of uncertain investment. Various RO models and valuation techniques are adopted and the critical analysis of the research trends and research hotspots in RO designs in CCS investments has not been made yet. This study employs a bibliometric analysis to examine the features of CCS literature including the research focus and trends as well RO uncertainty and models, types of options, and valuation techniques. The results present a comprehensive overview of the state-of-the-art which provides researchers a concrete basis for future research and directions for further development. This further provides energy and environmental policymakers and CCS project planners with valuable insights on various aspects of CCS policy and project design.Bisphenol A (BPA) is widely applied in industrial products and household products, leading to ubiquitous occurrences in environmental and biological samples. However, knowledge on human internal exposure to bisphenol analogues remains limited. ALK inhibitor Our study determined nine bisphenol analogues in urine samples collected from 1168 South China adults. BPA and bisphenol F (BPF) exhibited the highest detection frequencies in urine, i.e., 99.4% and 74.6%, respectively. BPA dominated over other analogues, with a median concentration of 1.74 μg/L, while BPF had a median concentration of 0.08 μg/L. Significant positive correlation was observed between urinary BPA and BPF (r = 0.201, p less then 0.01), indicating similar exposure sources or pathways of these two chemicals. Urinary BPA concentrations were significantly correlated with age, marital status, drinking status and history of hyperlipidemia (p less then 0.05). The median estimated daily intake (EDI) of Σ3BPs (the sum concentrations of BPA, BPF and BPAF) was determined to be 53.6 ng/kg-bw/day for adults. The EDIs were much lower than the temporary tolerable reference dose of BPA recommended by the European Food Safety Authority, indicating the bisphenol analogues presented no obvious health risks to South China adults.Estuarine systems are critical transition zones influenced by sea, land and freshwater. An array of human activities impacts these areas leading to multiple-stressor interactions. Temperature and salinity are among the most relevant drivers in estuaries, shaping species growth, reproduction and distribution. However, few studies provide an overview of cellular rewiring processes under multiple-stressor environments. Here, we tested how salinity could shape the response of ragworms Hediste diversicolor, an important bioindicator and commercial species, to elevated temperature. We exposed polychaetes to three temperatures for a month, simulating control, ocean warming and heatwave conditions (24, 27 and 30 °C, respectively) combined with two salinities (20 and 30). We quantified whole-organism performance (wet weight gain and survival), along with cellular stress response (CSR) and energy reserves of worms after 14 and 28 days of exposure. Significant three-way interactions between temperature, salinity and expculture and adaptive conservation strategies of estuarine systems.Organophosphate flame retardants (OPFRs), as a substitute for brominated flame retardants (BFRs), are widely used in industrial production and life. The presence of OPFRs in the environment has an adverse effect on the ecological environment system. This review provides comprehensive data for the occurrence of OPFRs and their diester metabolites (OP diesters) in wastewater treatment plants, surface water, drinking water, sediment, soil, air and dust in the environment. In particular, the accumulation and metabolism of OPFRs in organisms and the types of metabolites and metabolic pathways are discussed for animals and plants. In addition, the toxicity of OP triesters and OP diesters in organisms is discussed. Although research on OPFRs has gradually increased in recent years, there are still many gaps to be filled, especially for metabolic and toxicity mechanisms that need in-depth study. This review also highlights the shortcomings of current research and provides suggestions for a basis for future research on OPFRs.
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