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Biomorphic Ceramics: Functionality as well as Characterization associated with Preceramic Polymer-Modified Melanin.
CONCLUSIONS The study demonstrated that in the patients with atopic dermatitis the concentration of specific IgE was correlated with severity of the disease symptoms, including itch. This enables forecasting the course of the disease and selecting a group of patients who should immediately reduce their contact with allergen. © 2020 MEDPRESS.Research based on neuro-imaging findings indicate the presence of cerebral hypoperfusion (decreased blood flow) in children with autism spectrum disorders (ASD). One of modern therapeutic methods that can counteract cerebral hypoperfusion in those children is hyperbaric oxygen therapy (HBOT). AIM The aim of the present study was to examine whether a series of hyperbaric oxygen therapy sessions can improve selected psychosomatic parameters in children with ASD. MATERIALS AND METHODS The study group comprised 35 boys and 4 girls with ASD, who undertook 40 HBOT sessions consisting of breathing hyperbaric oxygen (1.5 atm.). Each session lasted 60 min. The following questionnaire tests were used to assess the effects of the therapy Clinical Global Impression Scale (CGIS), Autism Treatment Evaluation Checklist (ATEC), and Childhood Autism Rating Scale (CARS). RESULTS Eight components of the ATEC and CARS scales as well as the CARS total score revealed statistically significant improvements. One out of all examined items - ATEC Speech/language/communication - "Can follow some commands" revealed a decline after the HBOT sessions (p = 0.0431). CONCLUSIONS In younger children under study post-therapy improvements were found for the ATEC Sociability - "Does not imitate", ATEC Sensory/cognitive awareness - "Shows imagination", and ATEC Health/physical/behavior - "Sound-sensitive" items. In older children improvements were noted for ATEC Health/physical/behavior - "Obsessive speech" and CARS emotional response, adaptation to change, and total score. © 2020 MEDPRESS.The pathogenesis of functional dyspepsia is remains unknown. The diagnosis is based on subjective symptoms. However, many effort are being made in searching for the causes and objective indices which could facilitate the diagnosis and the treatment of this disease. AIM The aim of study was to evaluate the indices of serotonin synthesis and metabolism in patients with functional dyspepsia in relation to psychosomatic symptoms. MATERIALS AND METHODS The study comprised 30 healthy subjects (group I - control) and 30 patients with functional dyspepsia(group II) as postprandial distress syndrome (PDS), according to Rome Criteria IV. Assessment of the severity of dyspeptic symptoms was performed using a 10-point visual-analogue scale(VAS). All patients completed the Hamilton Depression Scale. Serum serotonin and 5-hydroxyindoleacetic acid (5-HIAA) concentration in urine were measured by ELISA method using IBL antibodies (catalog numbers- RE-59121, RE-59131). RESULTS Serum serotonin concentration in the control group was 205.1±34.1 ng/ml, and in dyspeptic patients - 154.2±52.9 ng/ml (p less then 0.001). Significant differences were also found in daily urinary 5-HIAA excretion 6.88±0.79 mg/24h vs 5.06±1.25 mg/24h, respectively ( p less then 0.001). Moreover, a negative correlation was found between serotonin concentration as well as urinary 5-HIAA excretion and severity of depressive symptoms. The correlation between severity of dyspeptic and psychic symptoms was poorly positive. CONCLUSIONS These results indicate that in patients with functional dyspepsia homeostasis of serotonin is disturbed, and it is in relation to psychosomatic symptoms. © 2020 MEDPRESS.As a long-term multisystem disorders, cardiovascular diseases can gravely affect on bone metabolism, prompting a severe bone loss and increasing predisposition to fractures and the development of osteoporosis. AIM The aim of the study was to analyze the peculiarities of bone mineral density (BMD), lipid spectrum, lipid peroxidation (LPO) and antioxidant system (AOS) activity in postmenopausal women with arterial hypertension (AH). learn more MATERIALS AND METHODS Using dual-energy X-ray absorptiometry, we measured BMD in 193 women aged 45-62 years with the Stage II of AH. Lipid profile, LPO and AOS status in blood plasma were determined. RESULTS In postmenopausal patients with hypertension, BMD and T-score values are significantly lower in comparison with the women of control group without hypertension (by 11.3% (p less then 0.05) and 14.4% (p less then 0.05) respectively). Independent predictors of osteoporosis progression in women with AHare the duration of disease, as well as menopause onset and the duration of postmenopausal period. In postmenopausal patients with AH there is a correlation dependence between the atherogenicity index and menopause duration (r=0.40, p less then 0.01), as well as the inverse correlation dependence between the atherogenicity index and the age of menopause onset (r =-0.27, p less then 0.01), which suggests that the earlier menopause in women with AH occurs, the faster the atherogenicity of plasma lipids progresses. Postmenopausal patients with AH showed higher indices of lipoperoxidation processes and simultaneous lower indices of antioxidant defence. CONCLUSIONS The bone mineral density in postmenopausal women with AH is significantly lower than in women of reproductive age. Independent predictors of osteoporosis progression in women with AH are the duration of disease, as well as menopause onset and the duration of postmenopausal period. © 2020 MEDPRESS.Background Professional caregivers are exposed to multiple stressors and have high burnout rates; however, not all individuals are equally susceptible. We investigated the association between resilience and burnout in a Swiss population of professional caregivers working in youth residential care. Methods Using a prospective longitudinal study design, participants (n = 159; 57.9% women) reported on burnout symptoms and sense of coherence (SOC), self-efficacy and self-care at four annual sampling points. The associations of individual resilience measures and sociodemographic variables, work-related and personal stressors, and burnout symptoms were assessed. Cox proportional hazards regressions were calculated to compute hazard ratios over the course of three years. Results Higher SOC, self-efficacy and self-care were related to lower burnout symptoms in work-related and personal domains. Higher SOC and self-efficacy were reported by older caregivers and by those with children. All three resilience measures were highly correlated.
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