Notes

Transcriptomic profiling regarding Gh/Igf technique shows a new caused tissue-specific difference and story hypoxia responsive family genes in gilthead seashore bream.
32%) by a hypercoagulable state (primary thrombophilia, protein C deficiency, factor V Leiden mutation, antiphospholipid antibody syndrome or prothrombin gene mutation) and paroxysmal nocturnal hemoglobinuria (1.63%). Cirrhosis was present in 18.7%, Portal vein thrombosis in 7.9%, and inferior vena cava thrombosis in 6.4%. The most common manifestations of BCS were ascites (29.9%) or acute kidney injury (18.8%) followed by hepatic encephalopathy (9.6%) and acute liver failure (5.6%).

This large population-based study from the United States showed increasing hospitalizations related to BCS. Common presentation was ascites and acute kidney injury.
This large population-based study from the United States showed increasing hospitalizations related to BCS. Common presentation was ascites and acute kidney injury.
Autoimmune hepatitis presenting as acute on chronic liver failure (AIH-ACLF) is a novel entity with limited data on clinical course and management. We assessed outcomes in patients of AIH-ACLF with no extrahepatic organ dysfunction/failure when administered steroids.

In this retrospective analysis, clinical data, laboratory parameters, liver biopsy indices and prognostic scores such as model for end-stage liver disease (MELD) and Child-Turcotte-Pugh (CTP) scores at baseline were computed for patients with AIH-ACLF and compared across strata of incident infections and transplant-free survival. The primary outcome was 90-day transplant-free survival. Biochemical remission was assessed, and predictors of end points were identified.

Twenty-nine patients of AIH-ACLF were included with a median follow-up of 4 months. The 90- and 180-daytransplant-free survival rates of 55.2 [95% confidence interval (CI) 39.7-76.6]% and 30.2(95% CI 16.7-54.6)%, respectively, were attained on steroids. Three patients (10.3%) une in MELD over 2 weeks.
Drug-induced liver injury (DILI) is an important cause of acute liver failure with significant morbidity and mortality. check details The outcome of DILI varies widely according to the drug implicated and the type of liver injury. Owing to the heterogeneous nature of liver injury, knowledge on clinical course and prognosis of DILI is limited. We had undertaken this study to determine the clinical characteristics, outcomes, and predictors of mortality in patients with DILI.

This prospective study was conducted from January 2015 through December 2018. We analyzed the drugs implicated, clinical course, and the outcome. Causality assessment was performed by using Roussel Uclaf Causality Assessment Method scoring. Patients were followed for 6 months until recovery/death or liver transplantation.

There were 133 cases with DILI. The mean age was 47.6 years, and 51.9% of them were men. Drugs causing DILI were antitubercular drugs (37.5%) followed by neuropsychiatric drugs (16.5%), antibiotics/antifungals (12%), complementary, bilirubin, albumin, and creatinine helpin predicting severity of liver injury and may help in triaging the patient for referral for liver transplantation.
Although DILI is uncommon, it has significant morbidity and mortality. Antitubercular drugs were the most common cause for DILI and DILI-related mortality in our study. Variables such as MELD, INR, bilirubin, albumin, and creatinine help in predicting severity of liver injury and may help in triaging the patient for referral for liver transplantation.A 53-year-old 10 pack year smoker and concrete worker for 12 years presented to us with a lung mass proven to be small cell lung cancer on lung biopsy. An industrial terminology of concrete cancer already exists defining the wear and tear in concrete due to various interactions. The interactions of concrete and smoke on lung, predisposed and increased the risk of lung cancer probably as an additive effect which we label as the medical concrete cancer of the lung.
Petrol pump workers are exposed to fumes emanated during petrol filling and vehicular exhaust thus falling prey to several respiratory diseases.

To assess the awareness and prevalence of respiratory morbidities among petrol pump workers of selected petrol pumps in Bangalore.

This cross-sectional study was conducted among 158 petrol pump workers from 11 selected pumps in Bengaluru. Following IEC approval, the baseline socio-demographic data, knowledge regarding respiratory morbidities and current morbidity pattern were ascertained. Medical examination and Peak Expiratory Flow rate (PEFR) was estimated.

The 158 workers were all male, mostly between 18-27 years (65.19%) and high school educated (49.37%). Knowledge regarding respiratory morbidities was 56%, while prevalence of respiratory morbidity was 61%. Those workers who had completed their higher education (>10
standard), earning monthly income (>Rs. 5000) had better knowledge regarding respiratory morbidities.

Pre-employment and regular medical examination including lung function tests and promotion of use of PPEs to be implemented.
Pre-employment and regular medical examination including lung function tests and promotion of use of PPEs to be implemented.
The construction industry is a leading contributor to occupational injuries. First Information Reports (FIRs) of Indian Police are a potential data source for construction injuries. The aim of this study was to estimate the completeness of ascertainment of construction site injuries by FIRs.

This was a two-sample capture-recapture study of construction site injuries sustained in the year 2017 in Delhi, India. The first capture sample was data extracted from FIRs. The second capture sample comprised data extracted from the Employee State Insurance Corporation (ESIC) and the Commissioners of Workmen Compensation. The Chapman estimator was used to estimate, with 95% confidence intervals, the total numbers of fatal and non-fatal injuries.

FIRs ascertained 374 injuries (110 fatal and 264 non-fatal) while the combined data of ESIC and workmen compensation claims ascertained 80 injuries (48 fatal and 32 non-fatal). The capture-recapture analysis estimated that 1,011 (95% CI 873 to 1149) injuries 258 (95% CI 22urther research is needed to identify reasons for some injuries not being reported to the police, in order to help to develop a strategy to improve the completeness of ascertainment of construction site injuries for the future.
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