Notes

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nt. GBS in Mexico still carries considerable mortality.
Verbal fluency test is a short psychometric test, which is sensitive to verbal ability and executive control impairment. We did not find studies that analyze verbal fluency in relation to the neurodevelopmental disorders in Spanish-speaking children with letters P-M. NSC 521777 Our objective was to analyze the verbal fluency of Spanish-speaking children with neurodevelopmental disorders.

We carried out a retrospective cross-sectional study to analyze the performance of children who had undergone a neuropsychological assessment.

We included 164 patients. There were 55 (33.54%) patients with low intellectual performance (LIP), 19 (11.59%) patients with dyslexia , and 90 (54.88%) patients had an ADHD. Patients with LIP showed lower phonological fluency than patients with ADHD. As for semantic fluidity, differences were observed between patients with LIP and ADHD and also between LIP and dyslexia. The probability of having LIP was 9.6 times greater when somebody had a scale score lower than 7 in the PF task and it was 16.7 times greater when the scale score was lower than 7 in the SF task.

There was a direct relationship between FSIQ and the performance in verbal fluency test, which is a brief and effective neuropsychological test in revealing deficits in executive functions, verbal abilities, and LIP.
There was a direct relationship between FSIQ and the performance in verbal fluency test, which is a brief and effective neuropsychological test in revealing deficits in executive functions, verbal abilities, and LIP.
Most patients presenting with acute vertigo are believed to suffer from acute, self-limited, presumed viral or post-viral vestibular neuritis (VN). But 25% of such cases can be "Pseudo VN", and are due to central causes, most often stroke. The aim of the present research was to study the sensitivity and specificity of Head Impulse, Nystagmus, Skew deviation (HINTS) battery for diagnosis of stroke in patients with acute-onset first episode of spontaneous vertigo.

Seventy-five patients who visited outpatient department or admitted between August 2014 and April 2016 with acute-onset first episode of spontaneous vertigo were included. Each patient was subjected to bedside oculomotor tests and HINTS. All patients underwent magnetic resonance imaging (MRI) of the brain. Stroke was diagnosed by MRI brain. If initial MRI brain was normal and still clinical signs favor stroke, repeat MRI brain-diffusion-weighted imaging study was done at 72 h after symptom onset to confirm the diagnosis. The sensitivity, specificity, positive predictive value, negative predictive value, accuracy and Youden's Index were used to quantify the diagnostic efficiency of HINTS at presentation against final MRI.

Patients presented with acute-onset first episode of spontaneous vertigo, HINTS battery was found to be more sensitive than the initial MRI of the brain done in first 24 h in diagnosing stroke (97.1 % Vs 82.9%). The specificity of the initial MRI of the brain and HINTS battery was 100.0 % and 80.0% respectively.

The HINTS battery was more sensitive than the initial MRI of the brain in diagnosing stroke in first 24 h in patients presented with acute-onset first episode of spontaneous vertigo.
The HINTS battery was more sensitive than the initial MRI of the brain in diagnosing stroke in first 24 h in patients presented with acute-onset first episode of spontaneous vertigo.To study the efficacy and safety of intravenous thrombolysis for the older acute ischemic stroke patients, clinical data were prospectively analyzed from 168 patients with acute ischemic stroke including 42 older adult patients (ET group), 66 younger patients (NET group) treated with rt-PA, and 60 older adult patients treated without rt-PA (ENT group). Stroke severity was assessed with an NIHSS score at baseline, 1-day and 14-day after treatment. Functional outcomes were evaluated by the modified Rankin scale and a Barthel index. Adverse effects were observed during the treatment. The rate of "good" prognosis was higher in the ET group than that in the ENT group at 90 days post-stroke. In older patients with stroke, thrombolytic therapy was found to be of greater benefit to patients with lower NIHSS scores at baseline, or patients classified as posterior circulation infarction, than for patients with higher NIHSS scores or infarctions located in other brain regions. Thrombolytic therapy may exhibit long-term efficacy by improving the future quality of life for older stroke patients with fewer bleeding risk factors and lower baseline NIHSS scores.
Small vessel disease (SVD) is the underlying anatomical substrate for both lacunar infarction and subcortical hemorrhage.

To assess predictive factors of ischemic or hemorrhagic stroke in patients with cerebral SVD.

Prospective hospital-based stroke registry ("The Sagrat Cor Hospital of Barcelona Stroke Registry") in an acute-care teaching hospital in Barcelona, Spain. From 4597 acute stroke patients included in the stroke registry over a 24-year period, 440 cases of lacunar stroke and 210 of subcortical intracerebral hemorrhage were selected. Demographics, clinical characteristics, risk factors, and early outcome were compared. Predictors of lacuna versus subcortical hemorrhage were assessed by multivariate analyses.

In a logistic regression model based on demographics, risk factors, clinical features and outcome, dyslipidemia (odds ratio [OR] 2.06 (95% confidence interval (CI) 1.17-3.62) and diabetes (OR 1.97, 95% CI 1.19-3.26) were independent risk factors for lacunar infarction. Anticoagulation therapy (OR 0.05, 95% CI 0.01-0.28), sudden onset (OR 0.51, 95% CI 0.33-0.78), motor symptoms (OR 0.44, 95% CI 0.26-0.76), headache (OR 0.23, 95% CI 0.12-0.41), altered consciousness (OR 0.10, 95% CI 0.05-0.21), respiratory complications (OR 0.19, 95% CI 0.08-0.46), and in-hospital death (OR 0.08, 95% CI 0.02-0.36) were predictors of subcortical hemorrhage.

Identification of differential clinical and prognostic profile between ischemic and hemorrhagic consequences of underlying cerebral SVD is useful for risk stratification in the current process pursuing precision medicine.
Identification of differential clinical and prognostic profile between ischemic and hemorrhagic consequences of underlying cerebral SVD is useful for risk stratification in the current process pursuing precision medicine.
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