Notes

Syndication involving Glutamatergic as well as Glycinergic Information onto Individual Hearing Chance Sensor Neurons.
Massage is a widely used alternative therapy among health professionals and parents for children with cerebral palsy (CP).

The review intended to determine the effects of massage on the rehabilitation of children with CP.

The research team conducted a literature review that examined the use of massage for children with various types of CP, such as ataxia, using relevant keywords. It included articles published up to December 2019. The research team searched the electronic databases PubMed, MEDLINE, Embase, Scopus, and the Cochrane Central Register of Controlled Trials.

The study took place at Eastern Mediterranean University in Famagusta, Cyprus.

Participants in the reviewed studies were children with CP.

The strength of the research designs was rated using Sackett's Levels of Evidence. The Physiotherapy Evidence Database (PEDro) scale was used to assess the studies' methodological quality. The outcome measures were classified according to the International Classification of Functioning, Disabilite and long-term effects of massage on all ICF's domains.
This study is a first review in this area and can be an important guide for professionals and caregivers who want properly use massage for children with CP. Massage as an adjunct to traditional therapies should be used to reduce muscle tone in spastic-type CP. More clear methods and relevant outcome measures should be used in future studies. Further studies with randomized controlled trials are required to determine massage type, massage applier, and oil for this population and to investigate immediate and long-term effects of massage on all ICF's domains.Copper is an essential micronutrient for the human body, taking part in several metabolic processes. this website It is required for the terminal oxidation, the elimination of free radicals, the proper functioning of iron metabolism, the synthesis of hormones, neurotransmitters and the stabilization of the extracellular matrix. Copper is a two-faced element. Its significance in protein-bounded form is undeniable, but free copper causes severe cell damage mainly through free radical reactions, substituting other essential metals in protein structure, and it has various effects on cell signaling pathways. The amount of copper present in the human body is part of a delicate balance. Both its deficiency and excess can develop severe symptoms and diseases. The nutritional copper balance is rarely broken, because the average daily consumption excessively covers the needs, and the body's copper stores can tolerate the temporary differences. Genetic diseases (Menkes and Wilson disease) helped to understand the copper metabolism and understand the clinical symptoms of deficiency and excessive intake. The role of copper in the development of chronic diseases is receiving increasing attention. Recent studies show its significance in neurodegenerative and cancerous diseases, both in pathogenesis and as a therapeutic target. Orv Hetil. 2020; 161(35) 1488-1496.Today, insulin hypersensitivity reactions are rare side effects of insulin therapy. In two-thirds of the suspected insulin allergy cases, the clinical symptoms are not related to insulin. The authors report the case of a 64-year-old female patient, by whom lymphocyte tarnsformation test (LTT) has been used to elucidate the background of allergic symptoms developed during insulin therapy. The performed LTT did not support hypersensitivity to insulin, however, the positive protamine test raised the suspicion of fish allergy. Complementary immunoserology also highlighted the coexistence of previously unrevealed thyroid disease. To our knowledge, this is the first documented case report in Hungary that attempts to address the real cause of a suspected hypersensitivity reaction to insulin by using LTT. Orv Hetil. 2020; 161(35) 1483-1487.
Swept-source optical coherence tomography is a useful non-invasive device that is used to understand better the role of choroid in the pathogenesis of diabetic retinopathy.

To measure choroidal thickness in diabetic eyes and to correlate it with established systemic risk factors, the severity and the therapy of diabetic retinopathy.

Prospective cross-sectional study using swept-source optical coherence tomography has been performed. Choroidal and macular thickness maps of 117 eyes of 60 diabetic patients were compared to data from 45 eyes of 24 healthy controls. In all diabetic patients, the systemic risk factors (duration and type of diabetes, blood hemoglobin A1C level, hypertension), the type (no, non-proliferative or proliferative) and the therapy of diabetic retinopathy were recorded, and their relation to choroidal thickness was evaluated using multiple regression models.

A significantly thinner choroid was measured in diabetic patients compared to controls (p<0.05). Analysing the whole cohorhickness significantly. Choroidal thickness is affected significantly by systemic risk factors (age, the presence of hypertension, disease duration). Choroidal thinning proved to be correlated with panretinal photocoagulation treatment of diabetic retinopathy. Orv Hetil. 2020; 161(35) 1475-1482.
Health is an important motivation for the consumption of both organic and functional foods. Organic food contains fewer pesticide residues and statistically more selected health-related compounds such as polyphenols in plant products and polyunsaturated fatty acids in milk and meat products. Recent studies suggest that the gut-liver axis plays an important role in the pathogenesis of non-alcoholic fatty liver disease, so probiotics could be a therapeutic tool. Comparing the health effects of yoghurt from organic origin with so-called conventional yoghurt is difficult, because there is no biomarker that would signal the difference with good specificity and sensitivity.

The aim of this study was to investigate numerous biomarkers to evaluate the difference between yoghurt from conventional and organic origin and their health effects in NAFLD.

We performed a prospective, cohort study consisting of 37 (age = 51.73 ± 11.82, male = 21, female = 16) patients with NAFLD at the 2nd Department of Internal Medicine of the Semmelweis University, Budapest.
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