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These aberrations were confirmed by real-time PCR. According to FISH analysis, the 8p23.1-p11.22 duplication was inverted. The ring chromosome originated from maternal chromosome 8. Targeted massive parallel sequencing did not reveal the KCNK9 mutations associated with Birk-Barel syndrome. Our data allow to assume that autosomal monosomy with inactive allele of imprinted gene arising from the loss of a ring chromosome in some somatic cells may be an etiological mechanism of mosaic imprinting disorders, presumably with less severe phenotype.Nonthermal plasma (NTP), or cold plasma, has shown many advantages in the agriculture sector as it enables removal of pesticides and contaminants from the seed surface, increases shelf life of crops, improves germination and resistance to abiotic stress. Recent studies show that plasma treatment indeed offers unique and environmentally friendly processing of different seeds, such as wheat, beans, corn, soybeans, barley, peanuts, rice and Arabidopsis thaliana, which could reduce the use of agricultural chemicals and has a high potential in ecological farming. This review covers the main concepts and underlying principles of plasma treatment techniques and their interaction with seeds. Different plasma generation methods and setups are presented and the influence of plasma treatment on DNA damage, gene expression, enzymatic activity, morphological and chemical changes, germination and resistance to stress, is explained. Important plasma treatment parameters and interactions of plasma species with the seed surface are presented and critically discussed in correlation with recent advances in this field. check details Although plasma agriculture is a relatively new field of research, and the complex mechanisms of interactions are not fully understood, it holds great promise for the future. This overview aims to present the advantages and limitations of different nonthermal plasma setups and discuss their possible future applications.In the United States, patients face increasing practical barriers and concerns about stigma when seeking sexual and reproductive healthcare, specifically family planning services involving hormonal contraception, emergency contraception, and abortion. The pharmacist is a member of the interprofessional care team with the ability to provide non-judgmental, high-quality, and patient-centered care. The community pharmacy setting itself offers specific advantages which promote access, including availability in most neighborhoods, broad hours of operation, lack of need for an appointment, and a stigma-free space which is frequented for other goods and services. This commentary suggests specific ways for pharmacies to improve access to contraception, emergency contraception, and abortion in line with national quality recommendations. Particular focus is given to the intersection of sexual and reproductive health resources and referrals within the pharmacy profession as well as the training and technical assistance tools which can help address unmet patient need.A new family of sterically hindered alkyl(tri-tert-butyl) phosphonium salts (n-CnH2n+1 with n = 2, 4, 6, 8, 10, 12, 14, 16, 18, 20) was synthesized and evaluated as stabilizers for the formation of palladium nanoparticles (PdNPs), and the prepared PdNPs, stabilized by a series of phosphonium salts, were applied as catalysts of the Suzuki cross-coupling reaction. All investigated phosphonium salts were found to be excellent stabilizers of metal nanoparticles of small catalytically active size with a narrow size distribution. In addition, palladium nanoparticles exhibited exceptional stability the presence of phosphonium salts prevented agglomeration and precipitation during the catalytic reaction.Domain adaptation aims to handle the distribution mismatch of training and testing data, which achieves dramatic progress in multi-sensor systems. Previous methods align the cross-domain distributions by some statistics, such as the means and variances. Despite their appeal, such methods often fail to model the discriminative structures existing within testing samples. In this paper, we present a sample-guided adaptive class prototype method, which consists of the no distribution matching strategy. Specifically, two adaptive measures are proposed. Firstly, the modified nearest class prototype is raised, which allows more diversity within same class, while keeping most of the class wise discrimination information. Secondly, we put forward an easy-to-hard testing scheme by taking into account the different difficulties in recognizing target samples. Easy samples are classified and selected to assist the prediction of hard samples. Extensive experiments verify the effectiveness of the proposed method.Palestinian-Arab women are at increased risk of cardiovascular disease due to high prevalence of diabetes and other risk factors. The current study investigates the effectiveness of an intensive group-based intervention on lifestyle habits that can prevent diabetes and cardiovascular disease. To that end, we conducted a group-based intervention based on the diabetes prevention program in two consecutive phases. The first phase consisted of a quasi-experimental study and the second phase included community-wide dissemination, with a 6-month follow-up. Findings from the quasi-experiment indicate increased consumption of fruit, vegetables and whole grains, weight reduction (-2.21 kg, p less then 0.01), and a significant increase in the average daily steps in the intervention group (from 4456 to 6404). Findings from the dissemination indicate that average daily vegetables consumption increased from 1.76 to 2.32/day as did physical activity and average daily steps (from 4804 to 5827). There was a significant reduction in blood pressure, total cholesterol and LDL. These gains were sustained over 6 months following the intervention. This community-based, culturally adapted, health-promotion intervention led to improved nutrition and physical activity which were maintained after 6 months. Collaboration with community centers and local community partners created an effective channel for dissemination of the program to pre-clinical individuals.
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