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The presence of oral symptoms and signs in many systemic diseases is not uncommon knowledge. Investigations that explore the relationship between systemic diseases and their oral manifestations are of particular interest to dentists, as this enables them to be better clinicians with an acumen to recognize, treat, or refer patients with the systemic disease to general physicians. This study was undertaken to understand the oral manifestations of systemic lupus erythematosus (SLE) with an emphasis on oral mucosal lesions, dental caries, and periodontitis.
A single institutional cross-sectional survey was conducted from September 2017 to July 2018 on a sample of 500 SLE patients attending the Institute of Rheumatology, Rajiv Gandhi Government General Hospital, Chennai. The dentition status, periodontal status, and oral mucosal lesions were assessed by a single trained and calibrated examiner using the World Health Organization (WHO) proforma, 2013. Besides, disease activity in SLE patients was assessed by rhbe concluded from the present study that SLE patients are more vulnerable to oral diseases than the general population. Furthermore, disease activity in SLE patients has a strong positive correlation with oral health status in SLE patients.
It can be concluded from the present study that SLE patients are more vulnerable to oral diseases than the general population. Furthermore, disease activity in SLE patients has a strong positive correlation with oral health status in SLE patients.
Obesity has become a challenge for global public health. The global prevalence of obesity has nearly doubled in the past decades (World Health Organization). Obesity may lead to changes in the sympathetic regulation of cardiovascular function, thus favoring the development of cardiovascular complications.
To find a correlation between various obesity indices (body mass index, waist-height ratio, waist circumference and waist-hip ratio) and heart rate recovery in healthy subjects.
A total of 100 apparently healthy subjects aged 18-30 years were enrolled and were divided into two groups on the absence and presence of a family history of cardiovascular disease. The treadmill testing was done in the exercise lab of the physiology department of the medical institute. Exercise testing of the subjects was conducted according to the standard Bruce protocols.
There was a negative correlation between various obesity indices and heart rate recovery but we did not get a statistically signification association between them.
In our study, we have found no statistically significant association between various obesity indices and heart rate recovery. Thus measuring obesity indices in the younger age group will not lead to much significance in terms of heart rate recovery and may be avoided.
In our study, we have found no statistically significant association between various obesity indices and heart rate recovery. SB939 solubility dmso Thus measuring obesity indices in the younger age group will not lead to much significance in terms of heart rate recovery and may be avoided.
Brain-derived neurotrophic factor (BDNF) plays an important role in repairing normal as well as in the injured brain. Physical exercise may have a positive impact on the release of BDNF.
PNF is a neurophysiological approach that facilitates the stimulation of central and peripheral nervous systems. In this study, our aim was to assess the levels of BDNF as well as functional recovery before and after the intervention of PNF in patients with acute stroke.
A total of 208 patients with first time confirmed stroke were recruited and assessed for stroke severity, type, mini-mental state exam (MMSE), functional independence measure scale, and BDNF levels before and after PNF intervention. BDNF levels were also assessed in healthy individuals for control values.
A significant decline in levels of BDNF was observed after in stroke. BDNF levels in patients (with different risk factors) with diabetes, hypertension and DM+ HTN, alcohol, and smoking history were 8.8 ± 4.04 ng/mL, 8.86 ± 4.68 ng/mL, 8.65 ± 3.26 ng/mL, 8.51 ± 4.26 ng/mL, and 8.9 ± 3.4 ng/mL, respectively. A decline in BDNF levels was observed in accordance with the severity of stroke in both ischemic and hemorrhagic stroke with the least level being in severe stroke (NIHSS >15 and ICH >3). Despite the type of stroke and the presence of risk factors, a significant improvement in BDNF levels and FIM scale scores was seen in all subjects who received PNF exercises.
Thus, PNF is efficient in improving functional level in acute stroke irrespective of the type of stroke and risk factors.
Thus, PNF is efficient in improving functional level in acute stroke irrespective of the type of stroke and risk factors.
Air pollution due to road traffic is a solemn health hazard and vehicular emissions due to huge population in the cities are the main reason for the air quality crisis. The study was conducted to assess the degree of impairment in lung function in traffic police personnel exposed to traffic pollution compared to less-exposed healthy subjects.
This comparative cross-sectional study was conducted among 250 traffic police personnel, aged 20-55 years, working in Chennai city, as compared to a matched control group, consisting of 250 less-exposed subjects. Measurement of pulmonary function testing was done with an RMS Helio 401. Statistical analysis was carried out with R statistical software.
The traffic police personnel had significantly (
< 0.05) declined FEV1 and FEV1/FVC ratio and FEF 25-75% (L/s) as compared to controls. Traffic personnel with longer duration of exposure showed significantly (
< 0.05) reduced lung functions than those with shorter duration. We have found a significant negative correlation with all pulmonary function parameters such as FVC, FEV1, FEV1/FVC, PEFR, and FVC 25%-75% among the traffic police personnel.
The impairment of pulmonary function among the traffic police personnel might be due to the effect of pollution by vehicular exhausts and they should be offered personal protective or preventive measures.
The impairment of pulmonary function among the traffic police personnel might be due to the effect of pollution by vehicular exhausts and they should be offered personal protective or preventive measures.
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